Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Želmíra Odlerová"'
Autor:
Zbynek Svoboda, Jiri Janota, Milan Slosarek, Zelmira Odlerova, Katarina Kralova, Jiri Kunes, Karel Waisser, Lenka Kubicova
Publikováno v:
Molecules, Vol 5, Iss 5, Pp 714-726 (2000)
A set of N,N'-diarylalkanediamides was synthesized. The compounds were tested for their antimycobacterial and antialgal activity. The antimycobacterial activity of N,N'-diarylalkanediamides depends on the lipophilicity of the respective acid. Antimyc
Externí odkaz:
https://doaj.org/article/be84fe7b9ecc4605a511aa44dc9c9cc2
Publikováno v:
Collection of Czechoslovak Chemical Communications. 63:698-712
Fifteen novel substituted azachalcone derivatives and their bis substituted analogs were prepared from 3,5-diacetyl-2,6-dimethylpyridine by the Claisen-Schmidt condensation. The influence of the reaction conditions on the yield of mono- and bischalco
Publikováno v:
Collection of Czechoslovak Chemical Communications. 62:510-515
A series of thirty 2,3-dithiabicyclo[3.3.0]octa-4,8-diene derivatives was examined for antimycobacterial activity against Mycobacterium tuberculosis, M. kansasii, M. avium, and M. fortuitum. The structure-activity relationships were analysed by Free-
Publikováno v:
Scopus-Elsevier
On the basis of a preliminary study of the antimycobacterial activity of thiobenzanilides, a group of 4'-isopropyl- and 4'-butylthiobenzanilides have been synthesized and tested against Mycobacterium tuberculosis, Mycobacterium kansasii, Mycobacteriu
Publikováno v:
Collection of Czechoslovak Chemical Communications. 61:791-798
A series of 5-alkylthio-1-aryltetrazoles 1-14 was prepared by alkylation of the corresponding 1-aryltetrazole-5-thiols with alkyl bromides in the cyclohexane-aqueous potassium hydroxide system. The new compounds were evaluated for their activity agai
Autor:
Karel Waisser, Želmíra Odlerová, Vera Klimesova, Miloš Macháček, Martin Svoboda, Vladimír Buchta
Publikováno v:
Archiv der Pharmazie. 329:438-442
A series of 4-alkylthiopyridine-2-carbothioamides have been prepared and evaluated in vitro for antimicrobial activity. Chemical structures have been demonstrated by IR and 1H NMR data and by elemental analysis. The antimycobacterial activity of thes
Publikováno v:
Collection of Czechoslovak Chemical Communications. 61:1109-1114
Homolytic alkylation of 6-chloro-2-pyrazinecarbonitrile by alkanoic acid and subsequent partial hydrolysis afforded 5-alkyl-6-chloro-2-pyrazinecarboxamides 1a-1e. Reaction of amides 1a-1e by Lawesson's reagent afforded corresponding thioamides 2a-2e.
Publikováno v:
Collection of Czechoslovak Chemical Communications. 61:1102-1108
A series of N-substituted 3-amino-5-thiocarbamoyl-2-pyrazinecarboxamides was prepared. The structure of compounds was confirmed by elemental analysis, IR and 1H NMR spectra. The results of in vitro antifugal and antimycobacterial susceptibility testi
Publikováno v:
Collection of Czechoslovak Chemical Communications. 60:1236-1241
Nucleophilic substitution of 3-chloro-5-cyano-2-pyrazinecarboxamide by substituted anilines afforded substituted 3-arylamino-5-cyano-2-pyrazinecarboxamides I-X. The structures of compounds were confirmed by elemental analysis, UV, IR and 1H NMR spect
Publikováno v:
Collection of Czechoslovak Chemical Communications. 59:234-238
Oxidation of 1-aryltetrazole-5-thiols afforded bis(1-aryltetrazol-5-yl) disulfides. The compounds were tested for antimycobacterial activity against Mycobacterium tuberculosis, M. kansasii, M. avium and M. fortuitum. In the case of M. tuberculosis, t