Urolithin A conjugation with NSAIDs inhibits its glucuronidation and maintains improvement of Caco-2 monolayers' barrier function.

Autor: Korczak M; Microbiota Lab, Medical University of Warsaw, Warsaw, Poland., Roszkowski P; Faculty of Chemistry, University of Warsaw, Warsaw, Poland., Skowrońska W; Department of Pharmaceutical Biology, Medical University of Warsaw, Warsaw, Poland., Żołdak KM; Microbiota Lab, Medical University of Warsaw, Warsaw, Poland., Popowski D; Microbiota Lab, Medical University of Warsaw, Warsaw, Poland; Department of Food Safety and Chemical Analysis, Prof. Wacław Dąbrowski Institute of Agricultural and Food Biotechnology - State Research Institute, Warsaw, Poland., Granica S; Department of Pharmaceutical Biology, Medical University of Warsaw, Warsaw, Poland., Piwowarski JP; Microbiota Lab, Medical University of Warsaw, Warsaw, Poland. Electronic address: jakub.piwowarski@wum.edu.pl.

Publikováno v: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2023 Dec 31; Vol. 169, pp. 115932. Date of Electronic Publication: 2023 Nov 24.