Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Špela Kos"'
Autor:
Maja Čemažar, Tanja Jesenko, Maša Bošnjak, Boštjan Markelc, Urška Kamenšek, Simona Kranjc Brezar, Špela Kos, Urša Lampreht Tratar, Katarina Žnidar, Andrej Renčelj, Urška Matkovič, Teja Valant, Kristina Levpušček, Živa Modic, Tilen Komel, Tim Božič, Urša Kešar, Barbara Starešinič, Katja Uršič Valentinuzzi, Monika Savarin, Primož Strojan, Gorana Gašljević, Maja Ota, Aleš Grošelj, Črt Jamšek, Rosana Hudej, Matjaž Peterka, Frenk Smrekar, Barbara Hubad, Marjan Hosta, Jaka Kužnik, Lojze Hosta, Damijan Miklavčič, Matej Reberšek, Aleksandra Cvetkoska, Anja Zajc, Janja Dermol-Černe, Nataša Tozon, Nina Milevoj, Alenka Nemec Svete, Gregor Serša
Publikováno v:
Onkologija, Vol 26, Iss 1 (2022)
Genska terapija postaja čedalje bolj zanimiva tudi v onkologiji. Med aplikacijami je morda najzanimivejša imunostimulacija. Pripravimo lahko plazmidno DNA, ki nosi zapis za različne imunostimulatorne molekule, ki jih vnesemo v celice tumorjev ali
Externí odkaz:
https://doaj.org/article/494c4547191a4dfe94028b207b9ba10f
Autor:
Tjaša Potočnik, Alenka Maček Lebar, Špela Kos, Matej Reberšek, Eva Pirc, Gregor Serša, Damijan Miklavčič
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2700 (2022)
The exact mechanisms of nucleic acid (NA) delivery with gene electrotransfer (GET) are still unknown, which represents a limitation for its broader use. Further, not knowing the effects that different experimental electrical and biological parameters
Externí odkaz:
https://doaj.org/article/ec855659dc454da794fd899e15e0bcdb
Autor:
Špela Kos, Gregor Serša
Publikováno v:
Onkologija, Vol 23, Iss 1, Pp 34-39 (2019)
DNA vakcine predstavljajo obetaven pristop imunoterapije raka, predvsem zaradi njihove enostavnosti, stabilnosti in varnosti. DNA vakcine temeljijo na vnosu plazmidne DNA z zapisom za enega ali več tumorskih antigenov, udeleženih v nastanku, napred
Externí odkaz:
https://doaj.org/article/347153ce7d7d4abebd0415ccfd090928
Autor:
Alessandra Lopes, Kevin Vanvarenberg, Špela Kos, Sophie Lucas, Didier Colau, Benoît Van den Eynde, Véronique Préat, Gaëlle Vandermeulen
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract DNA vaccination against cancer has become a promising strategy for inducing a specific and long-lasting antitumor immunity. However, DNA vaccines fail to generate potent immune responses when used as a single therapy. To enhance their activi
Externí odkaz:
https://doaj.org/article/8a185f7e782e4e90bd9cd7722f8cbb6c
Autor:
Andrea Jurov, Špela Kos, Nataša Hojnik, Ivana Sremački, Anton Nikiforov, Christophe Leys, Gregor Serša, Uroš Cvelbar
Publikováno v:
Applied Sciences, Vol 11, Iss 3, p 1266 (2021)
Plasma jets are extensively used in biomedical applications, particularly for exploring cell viability behaviour. However, many experimental parameters influence the results, including jet characteristics, secondary liquid chemistry and protocols use
Externí odkaz:
https://doaj.org/article/308755f9aa72463eaf3d1d64765e66f6
Autor:
Bostjan Markelc, Tanja Jesenko, Simona Kranjc Brezar, Masa Omerzel, Ursa Lampreht Tratar, Andrej Rencelj, Urska Matkovic, Katarina Znidar, Spela Kos, Kristina Levpuscek, Ziva Pisljar, Ursa Kesar, Tilen Komel, Tim Bozic, Aneja Tuljak, Rosana Hudej, Matjaz Peterka, Urska Kamensek, Andrej Cör, Gorana Gasljevic, Alenka Nemec Svete, Natasa Tozon, Gregor Sersa, Maja Cemazar
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Immunotherapeutic drugs are promising medicines for cancer treatment. A potential candidate for immunotherapy is interleukin-12 (IL-12), a cytokine well known for its ability to mediate antitumor activity. We developed a plasmid encoding hum
Externí odkaz:
https://doaj.org/article/31c16b9fe1ca4c038f2fb6e10cd7146e
Autor:
Andrea Jurov, Špela Kos, Tanja Blagus, Ivana Sremački, Gregor Filipič, Nataša Hojnik, Anton Nikiforov, Christophe Leys, Maja Čemažar, Gregor Serša, Uroš Cvelbar
Publikováno v:
Biointerphases. 17:021004
The possible benefits of an atmospheric pressure plasma jet skin treatment have been tested in vivo on mouse skin. Many studies have been conducted in vitro on mouse skin cells, but only a few in vivo where, due to the complexity of the biological sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d22d2fda0765f622bc76b6adad8f07d0
https://doi.org/10.1116/6.0001596
https://doi.org/10.1116/6.0001596
Autor:
Ana, Mitrović, Izidor, Sosič, Špela, Kos, Urša Lampreht, Tratar, Barbara, Breznik, Simona, Kranjc, Bojana, Mirković, Stanislav, Gobec, Tamara, Lah, Gregor, Serša, Janko, Kos
Publikováno v:
Oncotarget
Lysosomal cysteine peptidase cathepsin B, involved in multiple processes associated with tumor progression, is validated as a target for anti-cancer therapy. Nitroxoline, a known antimicrobial agent, is a potent and selective inhibitor of cathepsin B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::68ac19800c66f39cdfa5d522e7f196ec
https://pubmed.ncbi.nlm.nih.gov/28938624
https://pubmed.ncbi.nlm.nih.gov/28938624
Autor:
Urska Kamensek, Maja Cemazar, Simona Kranjc Brezar, Tanja Jesenko, Spela Kos, Katarina Znidar, Bostjan Markelc, Ziva Modic, Tilen Komel, Tim Gorse, Eva Rebersek, Helena Jakopic, Gregor Sersa
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1981 (2023)
DNA vaccination is one of the emerging approaches for a wide range of applications, including prophylactic vaccination against infectious diseases and therapeutic vaccination against cancer. The aim of this study was to evaluate the feasibility of ou
Externí odkaz:
https://doaj.org/article/e1458df429704fbe9b25838babe718fb
Autor:
Spela Kos, Masa Bosnjak, Tanja Jesenko, Bostjan Markelc, Urska Kamensek, Katarina Znidar, Urska Matkovic, Andrej Rencelj, Gregor Sersa, Rosana Hudej, Aneja Tuljak, Matjaz Peterka, Maja Cemazar
Publikováno v:
Pharmaceutics, Vol 13, Iss 10, p 1739 (2021)
Interleukin 12 (IL-12) is a key cytokine that mediates antitumor activity of immune cells. To fulfill its clinical potential, the development is focused on localized delivery systems, such as gene electrotransfer, which can provide localized delivery
Externí odkaz:
https://doaj.org/article/e0a9f59802f9407ca46068c68fbe54cd