Zobrazeno 1 - 10
of 218
pro vyhledávání: '"Šolaja Bogdan"'
Autor:
Opsenica Igor, Selaković Milica, Tot Mikloš, Verbić Tatjana, Srbljanović Jelena, Štajner Tijana, Đurković-Đaković Olgica, Šolaja Bogdan
Publikováno v:
Journal of the Serbian Chemical Society, Vol 86, Iss 2, Pp 115-123 (2021)
Synthesis of novel aminoquinoline derivatives has been accomplished and their activity against malaria strains has been examined. The compounds showed moderate in vitro antimalarial activity against two P. falciparum strains, 3D7 (CQ susceptible clon
Externí odkaz:
https://doaj.org/article/5bd031c2a9204f958ef62a741b70d077
Publikováno v:
Journal of the Serbian Chemical Society, Vol 81, Iss 11, Pp 1225-1230 (2016)
A novel and efficient route has been developed to afford 5H-dipyridoazepine derivatives from primary amines and 3,3'-(Z)-ethene-1,2-di-ylbis(4-chloropyridine). The procedure based on the double nucleophilic aromatic substitution provides a valuabl
Externí odkaz:
https://doaj.org/article/442a88a3699845fd86c32aa9868d2d57
Publikováno v:
Journal of the Serbian Chemical Society, Vol 80, Iss 7, Pp 839-852 (2015)
A series of new 5H-pyridobenzazepine and pyridobenzothiepine derivatives was synthesized by Pd-catalyzed formation of C-N and C-S bonds. All synthesized compounds were tested for their in vitro antimicrobial activity. The 5H-pyridobenzazepine deri
Externí odkaz:
https://doaj.org/article/b61a9fa803554637a887cd720ec5d7a4
Autor:
Opsenica Dejan M., Radivojević Jelena, Matić Ivana Z., Štajner Tijana, Knežević-Ušaj Slavica, Đurković-Đaković Olgica, Šolaja Bogdan A.
Publikováno v:
Journal of the Serbian Chemical Society, Vol 80, Iss 11, Pp 1339-1359 (2015)
New cyclohexylidene 1,2,4,5-tetraoxanes with polar guanidine and urea based groups were synthesized and evaluated for antimalarial activity against chloroquine resistant and susceptible Plasmodium falciparum strains. Derivatives showed moderate nM
Externí odkaz:
https://doaj.org/article/df329dab51e94fe78e661c48589bffc9
Autor:
Tot Mikloš, Opsenica Dejan M., Mitrić Milena, Burnett James C., Gomba Laura, Bavari Sina, Šolaja Bogdan A.
Publikováno v:
Journal of the Serbian Chemical Society, Vol 78, Iss 12, Pp 1847-1864 (2013)
Steroidal and adamantane aminoacridine derivatives were prepared and tested as both botulinum neurotoxin (BoNT) inhibitors and antimalarials. Steroid-bound acridines provided good potency against both the BoNT/A and BoNT/B light chains (LCs). The
Externí odkaz:
https://doaj.org/article/75226cb702de4637883a749ade6f9fc9
Autor:
Opsenica Dejan M., Šolaja Bogdan A.
Publikováno v:
Journal of the Serbian Chemical Society, Vol 74, Iss 11, Pp 1155-1193 (2009)
The problem of endemic malaria continues unabated globally. Malaria affects 40 % of the global population, causing an estimated annual mortality of 1.5-2.7 million people. The World Health Organization (WHO) estimates that 90 % of these deaths occur
Externí odkaz:
https://doaj.org/article/66f8dccae7f841c1b6e2aaa6a8d394f9
Publikováno v:
Journal of the Serbian Chemical Society, Vol 73, Iss 11, Pp 1021-1025 (2008)
Several tetraoxane and 4-aminoquinoline molecules were prepared in order to examine the influence of ribofuranose as a carrier molecule on the antimalarial activity of test compounds. The synthesized compounds showed pronounced antimalarial activity
Externí odkaz:
https://doaj.org/article/7decd83c55324aa0abd5aa231380e939
Autor:
Opsenica Igor, Opsenica Dejan, Jadranin Milka, Smith Kirsten, Milhous Wilbur K., Stratakis Manolis, Šolaja Bogdan
Publikováno v:
Journal of the Serbian Chemical Society, Vol 72, Iss 12, Pp 1181-1190 (2007)
Several dicyclohexylidene tetraoxanes were prepared in order to gain a further insight into structure-activity relationship of this kind of antimalarials. The tetraoxanes 2-5, obtained as a cis/trans mixture, showed pronounced antimalarial activity a
Externí odkaz:
https://doaj.org/article/22ff099dd36949a79ef058aa2ec43c93
Publikováno v:
Journal of the Serbian Chemical Society, Vol 70, Iss 3, Pp 329-345 (2005)
A three-dimensional QSAR pharmacophore model for antimalarial activity of steroidal 1,2,4,5-tetraoxanes was developed from a set of 17 substituted antimalarial derivatives out of 27 analogues that exhibited remarkable in vitro activity (below 100 ng/
Externí odkaz:
https://doaj.org/article/2a701ffd0c4c48f781d2e1bf0a56a04e
Publikováno v:
Journal of the Serbian Chemical Society, Vol 69, Iss 10, Pp 769-776 (2004)
Synthesis of a steroidal dendrimer core possessing various functional termini, such as ester, carboxy and hydroxy, is presented. The approach described enables further simple manipulations for the introduction of more complex functionalities.
Externí odkaz:
https://doaj.org/article/61c5fecda1484b77a9ffa94aa616ae23