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pro vyhledávání: '"Šarić Mustapić, Darija"'
Autor:
Šarić Mustapić, Darija
U svrhu ispitivanja inhibicijskog učinka flavonoida na metaboličku aktivnost enzima citokrom P450, primijenjene su reakcije biotransformacije: 6β-hidroksilacija testosterona (CYP3A4), O-demetilacija dekstrometorfana (CYP2D6), O-deetilacija fenacet
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https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c7ec86c4bd8da1d9d757ba25d64b5984
https://www.bib.irb.hr/1067465
https://www.bib.irb.hr/1067465
Oksidativni stres smatra se jednim od uzroka mnogih bolesti zapadne civilizacije kao što su Alzheimerova i Parkinsonova bolest, različita tumorska oboljenja i šećerna bolest. U sprječavanju i suportivnoj terapiji pacijenti često posežu za anti
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https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::ddb9edb8ca549c03e7d744a7fba5df2d
https://www.bib.irb.hr/993540
https://www.bib.irb.hr/993540
Flavonoidi su u ljudskoj prehrani (voću, povrću, čajevima ili ljekovitim biljkama) uvelike zastupljeni antioksidansi. Predstavljaju jednu od najbrojnijih skupina prirodnih heterocikličkih spojeva s kisikom, a do danas je opisano više od 4000 raz
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https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::8fef3e490369f993b93bf07fa15aef26
https://www.bib.irb.hr/1004455
https://www.bib.irb.hr/1004455
Flavonoids are group of secondary plant metabolites, derivatives of phenylchromone. They differentiate based on the structure of the dihydropyron ring and hydroxylation and subsequent methylation and glycosylation. Humans are exposed to flavonoid thr
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https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::343da19b85dac275572a96672092c8cf
https://www.bib.irb.hr/1017077
https://www.bib.irb.hr/1017077
Introduction: Flavonoids are class of compounds found in fruits and vegetables. Cytochrome P450 3A4 is one of the major enzymes for metabolism of xenobiotics and as such susceptible to flavonoid-drug interactions. In our previous study we have shown
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https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::687a18a922a8c767fbf1f4cf044e368d
https://www.bib.irb.hr/832937
https://www.bib.irb.hr/832937
Flavonoids are a big class of polyphenol compounds characterised with a phenyl chromane core. Their diversity comes from hydroxylation and subsequent methylation and glycosylation of the basic skeleton. These compounds are widely distributed in plant
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https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::4e95e468098524460efe9414eef607bd
https://www.bib.irb.hr/836967
https://www.bib.irb.hr/836967
Flavonoidi i fenolne kiseline su biološki aktivne sastavnice mnogih biljnih droga, propolisa i vina. Kao i drugi ksenobiotici, tako su i polifenoli podložni metaboličkoj eliminaciji iz organizma pri čemu prolaze kroz reakcije oksidacije, metilaci
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https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::d16ff07bc2f41c40f47624799507a7ff
https://www.bib.irb.hr/761393
https://www.bib.irb.hr/761393
Flavonoidi su derivati kromana s benzenskom jezgrom vezanom na položaju 2 ili 3. Hidroksilacija i metilacija hidroksilnih skupina na benzenskim jezgarama doprinosi raznolikosti ove skupine spojeva. Pojedini flavonoidi pokazuju raznolika farmakološk
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https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::27094213ed510b39aa4f4bc57d954de7
https://www.bib.irb.hr/762489
https://www.bib.irb.hr/762489
Flavonoidi su sekundarni metaboliti viših biljaka. Važni su sastojci ljudske prehrane, posebice voća i povrća te je za brojne flavonoide utvrđen pozitivan utjecaj na ljudsko zdravlje. Poput drugih ksenobiotika, u humanom organizmu, podložni su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::15ce4c85ba8b5ae625e7a64a72836ff6
https://www.bib.irb.hr/762491
https://www.bib.irb.hr/762491
Autor:
Šarić Mustapić, Darija1,2 darija.saric.mustapic@halmed.hr, Debeljak, Željko3,4 debeljak.zeljko@kbo.hr, Maleš, Željan5 zmales@pharma.hr, Bojić, Mirza6 mbojic@pharma.hr
Publikováno v:
Molecules. Oct2018, Vol. 23 Issue 10, p2553. 1p. 1 Diagram, 1 Chart, 2 Graphs.
