Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Šárka Šímová"'
Publikováno v:
Apoptosis. 13:423-436
TRAIL, a ligand of the TNFalpha family, induces upon binding to its pro-death receptors TRAIL-R1/DR4 and TRAIL-R2/DR5 the apoptosis of cancer cells. Activated receptors incite the formation of the Death-Inducing Signaling Complex followed by the acti
Autor:
Pavla Angelisova, Amandine Sansoni, Marie Malissen, Sylvie Richelme, Claude Grégoire, Dirk Reinhold, Luca Simeoni, Anja Schmidt-Giese, Vaclav Horejsi, Bernard Malissen, Burkhart Schraven, Ying Wang, Šárka Šímová
Publikováno v:
European Journal of Immunology
European Journal of Immunology, Wiley-VCH Verlag, 2007, 37 (11), pp.3259-69. ⟨10.1002/eji.200737563⟩
European Journal of Immunology, 2007, 37 (11), pp.3259-69. ⟨10.1002/eji.200737563⟩
European Journal of Immunology, Wiley-VCH Verlag, 2007, 37 (11), pp.3259-69. ⟨10.1002/eji.200737563⟩
European Journal of Immunology, 2007, 37 (11), pp.3259-69. ⟨10.1002/eji.200737563⟩
International audience; LIME (Lck-interacting membrane protein) is a transmembrane adaptor that associates with the Lck and Fyn protein tyrosine kinases and with the C-terminal Src kinase (Csk). To delineate the role of LIME in vivo, LIME-deficient m
Autor:
Pavel Lebduška, Marie Malissen, Petr Dráber, Petr Heneberg, Petra Volná, Lubica Dráberová, Viktor Bugajev, Bridget S. Wilson, Michael Boubelik, Šárka Šímová, Bernard Malissen, Vaclav Horejsi
Publikováno v:
The Journal of Experimental Medicine
Engagement of the Fcepsilon receptor I (FcepsilonRI) on mast cells and basophils initiates signaling pathways leading to degranulation. Early activation events include tyrosine phosphorylation of two transmembrane adaptor proteins, linker for activat
Publikováno v:
Journal of Biological Chemistry. 277:7955-7961
CD43 (leukosialin, sialophorin), an abundant leukocyte surface sialoglycoprotein, regulates leukocyte adhesion and transmits activating signals in T cells and dendritic cells. Immobilized anti-CD43 monoclonal antibody (mAb) MEM-59 has been previously
Autor:
Lukas Cermak, Tomas Valenta, Vladimír Kořínek, Lenka Doubravska, Ladislav Anděra, Šárka Šímová
Publikováno v:
Apoptosis : an international journal on programmed cell death. 13(4)
Wnt signaling enhances cell proliferation and the maintenance of hematopoietic cells. In contrast, cytotoxic ligand Apo2L/TRAIL induces the apoptosis of various transformed cells. We observed that co-culture of human pre-B leukemia cells KM3 and REH