Synthesis and In Silico Evaluation of Piperazine-Substituted 2,3-Dichloro-5,8-dihydroxy-1,4-naphthoquinone Derivatives as Potential PARP-1 Inhibitors.

Autor: Nemetova U; Engineering Faculty, Department of Chemistry, Organic Chemistry, Istanbul University-Cerrahpaşa, 34320 Istanbul, Turkey., Si Yah P; Department of Biochemistry, Faculty of Pharmacy, Bahcesehir University, 34353 Istanbul, Turkey., Boran T; Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Istanbul University-Cerrahpaşa, 34500 Istanbul, Turkey., Bi Lgi Ç; Faculty of Pharmacy, Department of Pharmacognosy, Istanbul University-Cerrahpaşa, 34500 Istanbul, Turkey., Özyürek M; Engineering Faculty, Department of Chemistry, Analytical Chemistry, Istanbul University-Cerrahpaşa, 34320 Istanbul, Turkey., Şahi Nler Ayla S; Engineering Faculty, Department of Chemistry, Organic Chemistry, Istanbul University-Cerrahpaşa, 34320 Istanbul, Turkey.

Publikováno v: ACS omega [ACS Omega] 2024 Sep 10; Vol. 9 (38), pp. 39733-39742. Date of Electronic Publication: 2024 Sep 10 (Print Publication: 2024).