Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Ş. Güniz Küçükgüzel"'
Publikováno v:
Proceedings, Vol 2, Iss 25, p 1573 (2018)
Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used as anti-inflammatory and analgesic agents. This family of drugs suppresses prostaglandin synthesis through inhibition of cyclooxygenase (COX) enzymes. Recent studies showed that anti-car
Externí odkaz:
https://doaj.org/article/b77fa821a1d04c118c7d49a6fcb558a7
Autor:
Amartya Basu, Tanaji T. Talele, Neerja Kaushik-Basu, Azize Şener, Özlem Bingöl Özakpınar, Derya Özsavcı, Özge Çevik, Göknur Aktay, Şule Gürsoy, Sevil Aydın, İnci Coşkun, Ş. Güniz Küçükgüzel
Publikováno v:
Molecules, Vol 18, Iss 3, Pp 3595-3614 (2013)
A series of novel N-(3-substituted aryl/alkyl-4-oxo-1,3-thiazolidin-2-ylidene)-4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamides 2a–e were synthesized by the addition of ethyl a-bromoacetate and anhydrous sodium acetate
Externí odkaz:
https://doaj.org/article/3975ad1428e64783b3b7460c52fc6a4a
Autor:
Göknil Pelin Coşkun, Teodora Djikic, Taha Bartu Hayal, Nezaket Türkel, Kemal Yelekçi, Fikrettin Şahin, Ş. Güniz Küçükgüzel
Publikováno v:
Molecules, Vol 23, Iss 8, p 1969 (2018)
Cyclooxygenase enzymes play a vital role in inflammatory pathways in the human body. Apart from their relation with inflammation, the additional involvement of COX-2 enzyme with cancer activity was recently discovered. In some cancer types the level
Externí odkaz:
https://doaj.org/article/b1e7e91058294a1dbb0abd7b05742faa
Publikováno v:
ARKIVOC, Vol 2008, Iss 12, Pp 188-194 (2008)
Externí odkaz:
https://doaj.org/article/32d525f1772c43b9a6648c264a59e19d
Publikováno v:
Journal of Biomolecular Structure and Dynamics. :1-12
In this work, twenty hydrazide-hydrazone and 4-thiazolidinone derivatives were synthesized starting from m-cresol. Antimicrobial evaluation was carried out by microdilution method against Enterococcus faecalis and Staphylococcus aureus as Gram-positi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dfe6d63240ddd4ecfd436b8432c6037
https://doi.org/10.1080/07391102.2022.2121761
https://doi.org/10.1080/07391102.2022.2121761
Publikováno v:
Medicinal Chemistry Research. 31:368-379
In the present study, the various 28 hybrid molecules containing hydrazone and sulfonate moiety were synthesized and characterized by FTIR, 1H-NMR, 13C-NMR spectroscopy and LC-MS spectrometry, besides elemental analysis. The compounds were evaluated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec213941953243000ea8023790ea9552
https://doi.org/10.1007/s00044-021-02837-z
https://doi.org/10.1007/s00044-021-02837-z
Publikováno v:
Journal of Research in Pharmacy. 26:1018-1029
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4322470fbda4b455e43313f92406556
https://doi.org/10.29228/jrp.97
https://doi.org/10.29228/jrp.97
Autor:
M.İhsan Han, Cansu Ümran Tunç, Pınar Atalay, Ömer Erdoğan, Gökhan Ünal, Mehmet Bozkurt, Ömer Aydın, Özge Çevik, Ş. Güniz Küçükgüzel
Publikováno v:
New Journal of Chemistry. 46:6046-6059
© 2022 The Royal Society of ChemistryIn this study, a series of novel (S)-Naproxen derivatives bearing a thiosemicarbazide/1,2,4-triazole moiety were designed, synthesized, and evaluated for anticancer activity. The structures of these compounds wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8cdc5afc08fd7a874253052da4278be
https://doi.org/10.1039/d1nj05899a
https://doi.org/10.1039/d1nj05899a
Autor:
Sevgi Gülyüz, Melike Sessevmez, Gokcen Ukuser, Melek Parlak Khalily, Selen Tiryaki, Tarik Sipahioglu, Kaan Birgül, Salih Özçubukçu, Dilek Telci, Ş. Güniz Küçükgüzel, Mahmut Durmus, Erdal Cevher, Ozgur Yilmaz
In this study, prostate cancer-targeted, drug-loaded PEtOx nanogel was prepared by the combination of living/cationic ring-opening polymerization and alkyne-azide cycloaddition “click” chemistry. A fluorescence probe was also conjugated with nano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc9821e4901ab7408cd7c85f181a0f00
https://doi.org/10.21203/rs.3.rs-2489117/v1
https://doi.org/10.21203/rs.3.rs-2489117/v1
Publikováno v:
Synthetic Communications. 51:2634-2643
In our continuing search for new anticancer agents, herein we report the synthesis of 2-(4-chloro-3-methylphenoxy)-N'-[(aryl)methylidene]acetohydrazides 3a–j and the evaluation of their anticancer ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee90775286eb522ab8c733426e657584
https://doi.org/10.1080/00397911.2021.1945105
https://doi.org/10.1080/00397911.2021.1945105