New insights in the mechanism of the SARS-CoV-2 M ^pro inhibition by benzisoselenazolones and diselenides.

Autor: Sancineto L; Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, Perugia, 06100, PG, Italy., Mangiavacchi F; Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, Perugia, 06100, PG, Italy., Dabrowska A; Virogenetics Laboratory of Virology, Malopolska Centre of Biotechnology, Jagiellonian University, Gronostajowa 7a, Krakow, 30-387, Poland.; Microbiology Department, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, Krakow, 30-387, Poland., Pacuła-Miszewska AJ; Department of Organic Chemistry, Faculty of Chemistry, Nicolaus Copernicus University, 7 Gagarin Street, Torun, Poland., Obieziurska-Fabisiak M; Department of Organic Chemistry, Faculty of Chemistry, Nicolaus Copernicus University, 7 Gagarin Street, Torun, Poland., Scimmi C; Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, Perugia, 06100, PG, Italy., Ceccucci V; Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, Perugia, 06100, PG, Italy., Kong J; Shanghai Institute for Advanced Immunochemical Studies, School of Life Science and Technology, ShanghaiTech University, Shanghai, China., Zhao Y; Shanghai Institute for Advanced Immunochemical Studies, School of Life Science and Technology, ShanghaiTech University, Shanghai, China., Ciancaleoni G; Dipartimento di Chimica e Chimica Industriale (DCCI), Università di Pisa, Via Giuseppe Moruzzi, 13, Pisa, 56124, Italy., Nascimento V; Departamento de Quımica Organica, Laboratorio de Sintese e Aplicaçao de Substancias Supramoleculares e Organocalcogenios (SupraSelen), Universidade Federal Fluminense, Outeiro Sao Joao Batista s/n, Niteroi, 24020-141, RJ, Brazil., Rizzuti B; Department of Physics, CNR-NANOTEC, SS Rende, University of Calabria, Rende, 87036, CS, Italy.; Institute of Biocomputation and Physics of Complex Systems, Joint Unit GBsC-CSIC-BIFI, University of Zaragoza, Zaragoza, 50018, Spain., Bortoli M; Department of Chemistry and Hylleraas Centre for Quantum Molecular Sciences, University of Oslo, Oslo, 0315, Norway., Orian L; Dipartimento di Scienze Chimiche, Università degli Studi di Padova, Padova, 35131, Italy., Kula-Pacurar A; Virogenetics Laboratory of Virology, Malopolska Centre of Biotechnology, Jagiellonian University, Gronostajowa 7a, Krakow, 30-387, Poland., Yang H; Shanghai Institute for Advanced Immunochemical Studies, School of Life Science and Technology, ShanghaiTech University, Shanghai, China., Ścianowski J; Department of Organic Chemistry, Faculty of Chemistry, Nicolaus Copernicus University, 7 Gagarin Street, Torun, Poland., Lei Y; Shanghai Institute for Advanced Immunochemical Studies, School of Life Science and Technology, ShanghaiTech University, Shanghai, China. leiying@shanghaitech.edu.cn., Pyrc K; Virogenetics Laboratory of Virology, Malopolska Centre of Biotechnology, Jagiellonian University, Gronostajowa 7a, Krakow, 30-387, Poland. k.a.pyrc@uj.edu.pl., Santi C; Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, Perugia, 06100, PG, Italy. claudio.santi@unipg.it.

Publikováno v: Scientific reports [Sci Rep] 2024 Oct 21; Vol. 14 (1), pp. 24751. Date of Electronic Publication: 2024 Oct 21.

Synthetic approach to iodosulfuron-methyl and metsulfuron-methyl metabolites and their application for water analysis.

Autor: Rakowiecki M; Synthex Technologies Sp. z o.o. Gagarina 7/134B 87-100 Toruń Poland budny@synthex.com.pl., Studzińska S; Department of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University Gagarina 7 87-100 Toruń Poland., Ścianowski J; Department of Organic Chemistry, Faculty of Chemistry, Nicolaus Copernicus University Gagarina 7 87-100 Toruń Poland., Bosiak MJ; Department of Organic Chemistry, Faculty of Chemistry, Nicolaus Copernicus University Gagarina 7 87-100 Toruń Poland.; Noctiluca S.A. Gagarina 7/41B 87-100 Toruń Poland., Wolan A; Synthex Technologies Sp. z o.o. Gagarina 7/134B 87-100 Toruń Poland budny@synthex.com.pl.; Department of Organic Chemistry, Faculty of Chemistry, Nicolaus Copernicus University Gagarina 7 87-100 Toruń Poland., Budny M; Synthex Technologies Sp. z o.o. Gagarina 7/134B 87-100 Toruń Poland budny@synthex.com.pl.

Publikováno v: RSC advances [RSC Adv] 2024 May 15; Vol. 14 (23), pp. 15848-15855. Date of Electronic Publication: 2024 May 15 (Print Publication: 2024).

Synthesis of New Chiral β -Carbonyl Selenides with Antioxidant and Anticancer Activity Evaluation-Part I.

Autor: Laskowska A; Department of Organic Chemistry, Faculty of Chemistry, Nicolaus Copernicus University, 7 Gagarin Street, 87-100 Torun, Poland., Pacuła-Miszewska AJ; Department of Organic Chemistry, Faculty of Chemistry, Nicolaus Copernicus University, 7 Gagarin Street, 87-100 Torun, Poland., Obieziurska-Fabisiak M; Department of Organic Chemistry, Faculty of Chemistry, Nicolaus Copernicus University, 7 Gagarin Street, 87-100 Torun, Poland., Jastrzębska A; Department of Analytical Chemistry and Applied Spectroscopy, Faculty of Chemistry, Nicolaus Copernicus University, 7 Gagarin Street, 87-100 Torun, Poland., Długosz-Pokorska A; Department of Biomolecular Chemistry, Faculty of Medicine, Medical University of Lodz, Mazowiecka 6/8, 92-215 Lodz, Poland., Gach-Janczak K; Department of Biomolecular Chemistry, Faculty of Medicine, Medical University of Lodz, Mazowiecka 6/8, 92-215 Lodz, Poland., Ścianowski J; Department of Organic Chemistry, Faculty of Chemistry, Nicolaus Copernicus University, 7 Gagarin Street, 87-100 Torun, Poland.

Publikováno v: Materials (Basel, Switzerland) [Materials (Basel)] 2024 Feb 15; Vol. 17 (4). Date of Electronic Publication: 2024 Feb 15.

Selected N -Terpenyl Organoselenium Compounds Possess Antimycotic Activity In Vitro and in a Mouse Model of Vulvovaginal Candidiasis.

Autor: Liang X; Department of Pharmaceutical Sciences, St. John's University, Queens, NY 11439, USA., Pacuła-Miszewska AJ; Faculty of Chemistry, Nicolaus Copernicus University, 87-100 Toruń, Poland., Obieziurska-Fabisiak M; Faculty of Chemistry, Nicolaus Copernicus University, 87-100 Toruń, Poland., Vartak R; Department of Pharmaceutical Sciences, St. John's University, Queens, NY 11439, USA., Mao G; Department of Pharmaceutical Sciences, St. John's University, Queens, NY 11439, USA., Patel K; Department of Pharmaceutical Sciences, St. John's University, Queens, NY 11439, USA., Fedosova NU; Department of Biomedicine, Aarhus University, 8000 Aarhus, Denmark., Ścianowski J; Faculty of Chemistry, Nicolaus Copernicus University, 87-100 Toruń, Poland., Billack B; Department of Pharmaceutical Sciences, St. John's University, Queens, NY 11439, USA.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2023 Oct 31; Vol. 28 (21). Date of Electronic Publication: 2023 Oct 31.

Facile synthesis of chiral phenylselenides as novel antioxidants and cytotoxic agents.

Autor: Laskowska A; Department of Organic Chemistry, Faculty of Chemistry, Nicolaus Copernicus University 7 Gagarin Street 87-100 Torun Poland pacula@umk.pl., Pacuła-Miszewska AJ; Department of Organic Chemistry, Faculty of Chemistry, Nicolaus Copernicus University 7 Gagarin Street 87-100 Torun Poland pacula@umk.pl., Obieziurska-Fabisiak M; Department of Organic Chemistry, Faculty of Chemistry, Nicolaus Copernicus University 7 Gagarin Street 87-100 Torun Poland pacula@umk.pl., Jastrzębska A; Department of Analytical Chemistry and Applied Spectroscopy, Faculty of Chemistry, Nicolaus Copernicus University 7 Gagarin Street 87-100 Torun Poland., Gach-Janczak K; Department of Biomolecular Chemistry, Faculty of Medicine, Medical University of Lodz 6/8 Mazowiecka Street 92-215 Lodz Poland., Janecka A; Department of Biomolecular Chemistry, Faculty of Medicine, Medical University of Lodz 6/8 Mazowiecka Street 92-215 Lodz Poland., Ścianowski J; Department of Organic Chemistry, Faculty of Chemistry, Nicolaus Copernicus University 7 Gagarin Street 87-100 Torun Poland pacula@umk.pl.

Publikováno v: RSC advances [RSC Adv] 2023 May 15; Vol. 13 (21), pp. 14698-14702. Date of Electronic Publication: 2023 May 15 (Print Publication: 2023).