Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Łukasz Ura"'
Autor:
Adam Kozierkiewicz, Alina Goralewska, Agnieszka Jankowska-Kulawy, Tomasz Judycki, Joanna Klimaszewska-Łata, Sylwia Kołtan, Barbara Kopeć, Olga M. Koper-Lenkiewicz, Krzysztof Łangowski, Andrzej Osuch, Urszula Rychlik, Andrzej Strug, Ilona Surożyńska-Godzina, Łukasz Ura, Rafał Wlazeł, Ewa Wysocka, Tomasz Zieliński, Bogdan Solnica
Publikováno v:
Diagnostyka Laboratoryjna. 58:21-30
In modern laboratory diagnostics, the flow of information in electronic form is common, more and more extensive, and complicated. For the flow of this information to be efficient and complete, it should include medical diagnostic laboratories and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cac079929c24ff6b67c97ec747732153
https://doi.org/10.5604/01.3001.0016.0234
https://doi.org/10.5604/01.3001.0016.0234
Autor:
Łukasz Uram, Magdalena Twardowska, Żaneta Szymaszek, Maria Misiorek, Andrzej Łyskowski, Zuzanna Setkowicz, Zuzanna Rauk, Stanisław Wołowiec
Publikováno v:
Molecules, Vol 29, Iss 18, p 4293 (2024)
In this study, we hypothesized that biotinylated and/or glycidol-flanked fourth-generation polyamidoamine (PAMAM G4) dendrimers could be a tool for efficient drug transport into glioma and liver cancer cells. For this purpose, native PAMAM (G4) dendr
Externí odkaz:
https://doaj.org/article/388197846c7346838192b9d8d6e98516
Autor:
Beata Krzykowska, Łukasz Uram, Wiesław Frącz, Miroslava Kovářová, Vladimir Sedlařík, Dominika Hanusova, Maciej Kisiel, Joanna Paciorek-Sadowska, Marcin Borowicz, Iwona Zarzyka
Publikováno v:
Polymers, Vol 16, Iss 18, p 2681 (2024)
In the present work, hybrid nanobiocomposites based on poly(3-hydroxybutyrate), P3HB, with the use of aromatic linear polyurethane as modifier and organic nanoclay, Cloisite 30B, as a nanofiller were produced. The aromatic linear polyurethane (PU) wa
Externí odkaz:
https://doaj.org/article/a3c57a291de440209153496f0ed5d3b3
Autor:
Magdalena Zaręba, Elżbieta Chmiel-Szukiewicz, Łukasz Uram, Justyna Noga, Magdalena Rzepna, Stanisław Wołowiec
Publikováno v:
Materials, Vol 17, Iss 16, p 3905 (2024)
One of the intensively developed tools for cancer therapy is drug-releasing matrices. Polyamidoamine dendrimers (PAMAM) are commonly used as nanoparticles to increase the solubility, stability and retention of drugs in the human body. Most often, dru
Externí odkaz:
https://doaj.org/article/12ca064fe1d14e15947357ec2057c747
Autor:
Łukasz Uram, Natalia Pieńkowska, Maria Misiorek, Żaneta Szymaszek, Magdalena Twardowska, Michał Siorek, Stanisław Wołowiec
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3226 (2024)
Glioblastoma multiforme therapy remains a significant challenge since there is a lack of effective treatment for this cancer. As most of the examined gliomas express or overexpress cyclooxygenase-2 (COX-2) and peroxisome proliferator-activated recept
Externí odkaz:
https://doaj.org/article/c0fd3aedc04e43f098696723226f234d
Autor:
Łukasz Uram, Konrad Wróbel, Małgorzata Walczak, Żaneta Szymaszek, Magdalena Twardowska, Stanisław Wołowiec
Publikováno v:
Molecules, Vol 28, Iss 17, p 6334 (2023)
Fulvestrant (F), lapatinib (L), and paclitaxel (P) are hydrophobic, anticancer drugs used in the treatment of estrogen receptor (ER) and epidermal growth factor receptor (EGFR)-positive breast cancer. In this study, glycidylated PAMAM G4 dendrimers,
Externí odkaz:
https://doaj.org/article/3060cd402a8e4dee9c4b9228b9f1451a
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 606 (2022)
α-Mangostin and vadimezan are widely studied potential anticancer agents. Their biological activities may be improved by covalent bonding by amide or ester bonds with the third generation poly(amidoamine) (PAMAM) dendrimer, substituted with α-D-glu
Externí odkaz:
https://doaj.org/article/535371ff3aba42278808b0e20e01d618
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 23, p 12925 (2021)
The natural xanthone α-mangostin (αM) exhibits a wide range of pharmacological activities, including antineoplastic and anti-nematode properties, but low water solubility and poor selectivity of the drug prevent its potential clinical use. Therefor
Externí odkaz:
https://doaj.org/article/ea5952e9ecae482ebbe215e093c03eae
Publikováno v:
Polymers, Vol 13, Iss 7, p 1049 (2021)
The generation 2 and 3 poly(amidoamine) dendrimers (PAMAM G2 and G3) were converted into N-(2,3-dihydroxy)propyl derivatives by the addition of enantiomerically pure S- and R-glycidol. The homochiral dendrimers bind to HaCaT and SCC-15 cell membranes
Externí odkaz:
https://doaj.org/article/e0992da5ef9d4aa3b40410c588329015
Autor:
Piotr Maj, Mattia Mori, Justyna Sobich, Joanna Markowicz, Łukasz Uram, Zbigniew Zieliński, Deborah Quaglio, Andrea Calcaterra, Ylenia Cau, Bruno Botta, Wojciech Rode
Publikováno v:
Molecules, Vol 25, Iss 12, p 2894 (2020)
With the aim to identify novel inhibitors of parasitic nematode thymidylate synthase (TS), we screened in silico an in-house library of natural compounds, taking advantage of a model of nematode TS three-dimensional (3D) structure and choosing candid
Externí odkaz:
https://doaj.org/article/999f4eff582449428a6208401ac6f6a0