Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Łukasz Kuźbicki"'
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-7 (2017)
Abstract Background Histone demethylase JARID1B plays several context dependent roles in epigenetic regulation of cellular differentiation in normal development and is highly expressed in multiple human cancers. The protein is a strong transcriptiona
Externí odkaz:
https://doaj.org/article/9939d6d0207b4118b04cbf41d4040e60
Publikováno v:
Folia Histochemica et Cytobiologica, Vol 49, Iss 3, Pp 381-388 (2011)
The aim of our study was to elucidate the possible involvement of COX-2 in the development and/or progression of nonmelanocytic skin lesions. To evaluate the usefulness of that enzyme as a potential molecular marker, we examined the intensity and spa
Externí odkaz:
https://doaj.org/article/c805b206e94241b3916733a7feb45717
Autor:
Łukasz Kuźbicki, Anna A. Brożyna
Publikováno v:
Cancer Investigation. 40:852-867
Although most melanocytic skin lesions are correctly diagnosed, numerous studies have shown interobserver disagreement. This review analyzes 20 molecules as immunohistochemical markers for distinguishing dysplastic and/or Spitz nevi from early melano
Autor:
Łukasz Kuźbicki, Anna A. Brożyna
Publikováno v:
Journal of Cutaneous Pathology. 49:1074-1089
Some intraepidermal lesions, even the nonmelanocytic ones, may mimic melanoma in situ. The cytoplasmic clarity in atypical basal cells, architectural disorder with cell aggregates or nest-like structures within the epidermis often cause challenge par
Autor:
Paweł Ossowski, Arkadiusz Kuś, Wojciech Krauze, Szymon Tamborski, Michał Ziemczonok, Łukasz Kuźbicki, Maciej Szkulmowski, Małgorzata Kujawińska
Publikováno v:
Biomed Opt Express
We present a holographic tomography technique in which the projections are acquired using both wavelength and illumination scanning in the near-infrared region. We show how to process the acquired data to obtain correct values of three-dimensional re
Autor:
Anna A. Brożyna, Łukasz Kuźbicki
Publikováno v:
Applied Immunohistochemistry & Molecular Morphology.
Permanent, elevated expression of cyclooxygenase-2 (COX-2) in keratinocytes of epidermis can stimulate its hyperplasia and constitute a factor promoting cancer development, as demonstrated in animal models. Intratumoral level and localization of COX-
Publikováno v:
Oncotarget
// Łukasz Kuźbicki 1 , Dariusz Lange 2 , Agata Stanek-Widera 2 , Agnieszka Glinska 1 and Barbara W. Chwirot 1 1 Department of Medical Biology, Faculty of Biology and Environment Protection, Nicolaus Copernicus University, Torun, Poland 2 Department
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-7 (2017)
BMC Cancer
BMC Cancer
Background Histone demethylase JARID1B plays several context dependent roles in epigenetic regulation of cellular differentiation in normal development and is highly expressed in multiple human cancers. The protein is a strong transcriptional repress
Publikováno v:
Pathology - Research and Practice. 210:591-595
Cyclooxygenase-2 (COX-2), overexpressed in many types of human cancer, may be a valuable marker for human melanoma. However, there are discrepancies between expression levels detected by different groups. The majority of the studies were carried out
Publikováno v:
Melanoma research. 26(5)
Because of the well-known heterogeneity of melanomas, prognosis of the disease is often difficult to assess even for lesions classified in similar stages. The aim of this study was to assess the usefulness of COX-2 as a melanoma prognostic marker and