Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Łukasz, Skalniak"'
Autor:
Joanna Klimek, Oskar Kruc, Joanna Ceklarz, Beata Kamińska, Bogdan Musielak, Robin van der Straat, Alexander Dӧmling, Tad A. Holak, Damian Muszak, Justyna Kalinowska-Tłuścik, Łukasz Skalniak, Ewa Surmiak
Publikováno v:
Molecules, Vol 29, Iss 11, p 2646 (2024)
The PD-1/PD-L1 complex is an immune checkpoint responsible for regulating the natural immune response, but also allows tumors to escape immune surveillance. Inhibition of the PD-1/PD-L1 axis positively contributes to the efficacy of cancer treatment.
Externí odkaz:
https://doaj.org/article/a5d831ce94ba4f578f5a3ee0930719c2
Autor:
Aleksandra Wesełucha-Birczyńska, Anna Kołodziej, Małgorzata Świętek, Łukasz Skalniak, Elżbieta Długoń, Maria Pajda, Marta Błażewicz
Publikováno v:
Nanomaterials, Vol 11, Iss 11, p 2890 (2021)
Poly(ε-caprolactone) (PCL) is a biocompatible resorbable material, but its use is limited due to the fact that it is characterized by the lack of cell adhesion to its surface. Various chemical and physical methods are described in the literature, as
Externí odkaz:
https://doaj.org/article/170ad1ef57dd4f039b610648531f8551
Autor:
Natalia Kłeczek, Janusz Malarz, Barbara Gierlikowska, Łukasz Skalniak, Agnieszka Galanty, Anna K. Kiss, Anna Stojakowska
Publikováno v:
Molecules, Vol 26, Iss 15, p 4644 (2021)
Carpesium divaricatum Sieb. & Zucc., a traditional medicinal plant used as an inflammation-relieving remedy, is a rich source of terpenoids. At least 40 germacrane-type sesquiterpene lactones, representatives of four different structural groups, were
Externí odkaz:
https://doaj.org/article/ca788f45fb764e82a7b67378ba8894f5
Autor:
Anna Kołodziej, Aleksandra Wesełucha-Birczyńska, Elżbieta Długoń, Małgorzata Świętek, Maciej Gubernat, Łukasz Skalniak, Marta Błażewicz
In response to the growing need for development of modern biomaterials for applications in regenerative medicine strategies, the research presented here investigated the biological potential of two types of polymer nanocomposites. Graphene oxide (GO)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f1e01bea981c9ffe5c54fe0253962f2
https://ruj.uj.edu.pl/xmlui/handle/item/307114
https://ruj.uj.edu.pl/xmlui/handle/item/307114
Autor:
Dariusz Cież, Sonia Głomb, Krzysztof Kozieł, Daniel Kamzol, Aleksandra Pałasz, Łukasz Skalniak, Kinga Czarnota, Katarzyna Jedrzejowska, Krystian Latos, Bogdan Musielak, Szymon Buda, Bartłomiej Bazan
Publikováno v:
Organic & Biomolecular Chemistry. 19:6045-6058
New bioorthogonal cycloaddition of 5-arylidene derivatives of 1,3-dimethylbarbituric acid as 1-oxa-1,3-butadienes and vinyl thioether as a dienophile has been applied to imaging inside living cells. The reaction is high yielding, selective, and fast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7065c106a7f2b9482921c11951ec121
https://doi.org/10.1039/d1ob00697e
https://doi.org/10.1039/d1ob00697e
Autor:
Anna Stojakowska, Anna K. Kiss, Natalia Kłeczek, Łukasz Skalniak, Agnieszka Galanty, Barbara Gierlikowska, Janusz Malarz
Publikováno v:
Molecules
Volume 26
Issue 15
Molecules, Vol 26, Iss 4644, p 4644 (2021)
Volume 26
Issue 15
Molecules, Vol 26, Iss 4644, p 4644 (2021)
Carpesium divaricatum Sieb. &
Zucc., a traditional medicinal plant used as an inflammation-relieving remedy, is a rich source of terpenoids. At least 40 germacrane-type sesquiterpene lactones, representatives of four different structural grou
Zucc., a traditional medicinal plant used as an inflammation-relieving remedy, is a rich source of terpenoids. At least 40 germacrane-type sesquiterpene lactones, representatives of four different structural grou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::966e595d1abcdfd5027eba47b10f0a7b
Autor:
Natalia, Kłeczek, Janusz, Malarz, Barbara, Gierlikowska, Łukasz, Skalniak, Agnieszka, Galanty, Anna K, Kiss, Anna, Stojakowska
Publikováno v:
Molecules
Carpesium divaricatum Sieb. & Zucc., a traditional medicinal plant used as an inflammation-relieving remedy, is a rich source of terpenoids. At least 40 germacrane-type sesquiterpene lactones, representatives of four different structural groups, were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dcef3bd0a430cd649759e3fa5a86fbad
https://pubmed.ncbi.nlm.nih.gov/34361797
https://pubmed.ncbi.nlm.nih.gov/34361797
Autor:
Maciej Siedlar, Jacek Plewka, Tad A. Holak, Ewa Surmiak, Alexander Dömling, Radoslaw Kitel, Małgorzata Stec, Bogdan Musielak, Łukasz Skalniak, Dominik Sala, Justyna Kocik, Damian Muszak, Katarzyna Magiera-Mularz
Here, we report a novel class of potent PD-L1/PD-1 inhibitors based on the rigidified biphenyl-inspired structure – terphenyls. Using in-silico docking, we designed and later experimentally shown the efficacy of terphenyl-based scaffolds to inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03bbce1028d9973f77ca50e688e6729b
https://doi.org/10.26434/chemrxiv.13849442.v1
https://doi.org/10.26434/chemrxiv.13849442.v1
Autor:
Stanisław Malicki, Grzegorz Dubin, Tad A. Holak, Adam Dubin, Mirosław Książek, Katarzyna Pels, Łukasz Skalniak, Dobroslawa Krzemien, Mariusz Madej, Aleksandra Pecak, Benedykt Wladyka
Publikováno v:
Nucleic acid therapeutics. 30(5)
CD44 is a type I transmembrane glycoprotein interacting with a number of extracellular components, including hyaluronic acid (HA). CD44-HA axis is involved in a variety of processes, including adhesion, migration, differentiation, trafficking, and ot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5af623651d456e0aafffd469a931b08c
https://pubmed.ncbi.nlm.nih.gov/32379519
https://pubmed.ncbi.nlm.nih.gov/32379519
Autor:
Marta Błażewicz, Małgorzata Świętek, Elżbieta Długoń, Aleksandra Wesełucha-Birczyńska, Paulina Moskal, Łukasz Skalniak, Anna Kołodziej
Publikováno v:
Journal of Molecular Structure. 1217:128342
Polymer nanocomposites obtain many new functional properties by adding appropriate nanoparticles, making them more suitable for applications in tissue engineering. The subjects of the presented research are nanocomposites composed of poly(e-caprolact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3cce8618df94932df8accf9bc4b5deb
https://doi.org/10.1016/j.molstruc.2020.128342
https://doi.org/10.1016/j.molstruc.2020.128342