Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Ľudmila Okruhlicová"'
1
Akademický článek
Biological Effects of Hydrogen Water on Subjects with NAFLD: A Randomized, Placebo-Controlled Trial
Autor: Branislav Kura, Maria Szantova, Tyler W. LeBaron, Viliam Mojto, Miroslav Barancik, Barbara Szeiffova Bacova, Barbora Kalocayova, Matus Sykora, Ludmila Okruhlicova, Narcisa Tribulova, Anna Gvozdjakova, Zuzana Sumbalova, Jarmila Kucharska, Xenia Faktorova, Martina Jakabovicova, Zuzana Durkovicová, Jan Macutek, Michaela Koscová, Jan Slezak
Publikováno v: Antioxidants, Vol 11, Iss 10, p 1935 (2022)
Non-alcoholic fatty liver disease (NAFLD) is a liver pathology affecting around 25% of the population worldwide. Excess oxidative stress, inflammation and aberrant cellular signaling can lead to this hepatic dysfunction and eventual carcinoma. Molecu
Externí odkaz: https://doaj.org/article/78492bccc7c243069c64150b3d5844c1
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2
Akademický článek
The effect of omega- 3 polyunsaturated fatty acids on endothelial tight junction occludin expression in rat aorta during lipopolysaccharide-induced inflammation
Autor: Jakub Krizak, Karel Frimmel, Iveta Bernatova, Jana Navarova, Ruzena Sotnikova, Ludmila Okruhlicova
Publikováno v: Iranian Journal of Basic Medical Sciences, Vol 19, Iss 3, Pp 290-299 (2016)
Objective(s): Occludin is essential for proper assembly of tight junctions (TJs) which regulate paracellular endothelial permeability. Omega-3 polyunsaturated fatty acids (Ω-3 PUFA) protect endothelial barrier function against injury. Materials and
Externí odkaz: https://doaj.org/article/cd658977ae55435f8a1c9cba62477871
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3
Akademický článek
Quercetin Improves Postischemic Recovery of Heart Function in Doxorubicin-Treated Rats and Prevents Doxorubicin-Induced Matrix Metalloproteinase-2 Activation and Apoptosis Induction
Autor: Monika Barteková, Petra Šimončíková, Mária Fogarassyová, Monika Ivanová, Ľudmila Okruhlicová, Narcisa Tribulová, Ima Dovinová, Miroslav Barančík
Publikováno v: International Journal of Molecular Sciences, Vol 16, Iss 4, Pp 8168-8185 (2015)
Quercetin (QCT) is flavonoid that possesses various biological functions including anti-oxidative and radical-scavenging activities. Moreover, QCT exerts some preventive actions in treatment of cardiovascular diseases. The aim of present study was to
Externí odkaz: https://doaj.org/article/e445f61c17494443aad3722c0b9c050a
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4
Quercetin Improves Postischemic Recovery of Heart Function in Doxorubicin-Treated Rats and Prevents Doxorubicin-Induced Matrix Metalloproteinase-2 Activation and Apoptosis Induction
Autor: Ľudmila Okruhlicová, Mária Fogarassyová, Narcisa Tribulova, Ima Dovinova, Monika Bartekova, Miroslav Barancik, Petra Šimončíková, Monika Ivanova
Publikováno v: International Journal of Molecular Sciences, Vol 16, Iss 4, Pp 8168-8185 (2015)
International Journal of Molecular Sciences
Volume 16
Issue 4
Pages 8168-8185
Quercetin (QCT) is flavonoid that possesses various biological functions including anti-oxidative and radical-scavenging activities. Moreover, QCT exerts some preventive actions in treatment of cardiovascular diseases. The aim of present study was to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ddef73520a99cb68614e5e0b0975f7
http://www.mdpi.com/1422-0067/16/4/8168
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5
Protection of the vascular endothelium in experimental situations
Autor: Vladimir Knezl, Zuzana Broskova, Ružena Sotníková, Viktor Bauer, Katarína Drábiková, Katalin Szöcs, Štefan Bezek, Jana Navarová, Zuzana Kyseľová, V Kristová, Peter Křenek, Ján Dřímal, Jana Nedelcevova, Iveta Bernatova, Ľudmila Okruhlicová, Viera Nosáľová
Publikováno v: Interdisciplinary Toxicology
Protection of the vascular endothelium in experimental situationsOne of the factors proposed as mediators of vascular dysfunction observed in diabetes is the increased generation of reactive oxygen species (ROS). This provides support for the use of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffc4260d5b630f6b78c493dea89e6bc0
https://doi.org/10.2478/v10102-011-0005-y
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6
Chronic cardiotoxicity of doxorubicin involves activation of myocardial and circulating matrix metalloproteinases in rats
Autor: Narcisa Tribulova, Ima Dovinova, Monika Bartekova, Monika Ivanova, Miroslav Barancik, Jana Vlkovicova, Petra Šimončíková, Ľudmila Okruhlicová
Publikováno v: Acta pharmacologica Sinica. 33(4)
To investigate the role of matrix metalloproteinases (MMPs) in the responses of rats to a prolonged doxorubicin (DOX) treatment. Male Wistar rats were used. DOX was administered by intraperitoneal injections of seven doses (cumulative dose was 15 mg/
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::355c210c31f6939b8d22f9cc30fc4a04
https://pubmed.ncbi.nlm.nih.gov/22447222
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7
Akademický článek
Differences in Distribution and Biological Effects of F3O4@PEG Nanoparticles in Normotensive and Hypertensive Rats—Focus on Vascular Function and Liver
Autor: Andrea Micurova, Michal Kluknavsky, Silvia Liskova, Peter Balis, Martin Skratek, Ludmila Okruhlicova, Jan Manka, Iveta Bernatova
Publikováno v: Biomedicines, Vol 9, Iss 12, p 1855 (2021)
We investigate the distribution and biological effects of polyethylene glycol (PEG)-coated magnetite (Fe3O4@PEG) nanoparticles (~30 nm core size, ~51 nm hydrodynamic size, 2 mg Fe/kg/day, intravenously, for two days) in the aorta and liver of Wistar
Externí odkaz: https://doaj.org/article/8c36987efbeb435dbd8f6b79bc7bab6c
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