Zobrazeno 1 - 10
of 98
pro vyhledávání: '"İrfan Ç"'
Autor:
Osman K., Ahmet K., Hilmi T., İlker N.O., Ercan Ö., Devrim Ç., Murat S., Emre Ç., İlhan H., Mustafa G., Yüksel Ü., Bahiddin Y., Cihan E., Mehmet Ali N. Ş., Emrah E., Umut D., Zeynep O., Mehmet Ali K., Ali G., İvo G., Erkan Ö., Muhammet B.H., Bülent E., Selma D., Sernaz U., Mahmut G., Hakan G., İrfan Ç.
Publikováno v:
Balkan Journal of Medical Genetics, Vol 25, Iss 2, Pp 5-14 (2022)
The demographic and clinical characteristics of patients who have BRCA 1/BRCA 2 pathogenic/likely pathogenic variants may differ from their relatives who had BRCA-related cancer. In this study, we aimed to demonstrate the clinical and demographic fin
Externí odkaz:
https://doaj.org/article/c0cbaea0ff6d4a069d5e79ca2869ea80
Autor:
Irfan Cicin, Elizabeth R. Plimack, Howard Gurney, Raya Leibowitz, Boris Y. Alekseev, Francis X. Parnis, Avivit Peer, Andrea Necchi, Joaquim Bellmunt, Hiroyuki Nishiyama, Jason Clark, Mihaela Munteanu, Ritesh Kataria, Calvin Jia, Thomas Powles, Cora N. Sternberg
Publikováno v:
BMC Cancer, Vol 23, Iss S1, Pp 1-11 (2024)
Abstract Background Indoleamine 2,3-dioxygenase 1 (IDO1) levels correlate with poor outcomes in urothelial carcinoma (UC). IDO1 and programmed death-ligand 1 (PD-L1) are often co-expressed. Epacadostat is a potent and highly selective inhibitor of ID
Externí odkaz:
https://doaj.org/article/263d9199baf8485699909ce6591e41d9
Autor:
Loic Verlingue, Antoine Italiano, Hans Prenen, Eva Maria Guerra Alia, Diego Tosi, Ruth Perets, Iwona Lugowska, Vladimir Moiseyenko, Mahmut Gumus, Cagatay Arslan, Colin R. Lindsay, Sanjeev Deva, Álvaro Taus, Ana Oaknin, Sylvie Rottey, Irfan Cicin, Sema Sezgin Goksu, Alexey Smolin, Susana Roselló-Keränen, Christin Habigt, Daniel Marbach, Christophe Boetsch, David Dejardin, Nassim Sleiman, Stefan Evers, Muriel Richard, Caroline Ardeshir, Jehad Charo, Anton Kraxner, Volker Teichgräber, Nino Keshelava, Rafal Dziadziuszko
Publikováno v:
EBioMedicine, Vol 109, Iss , Pp 105374- (2024)
Summary: Background: Simlukafusp alfa (FAP-IL2v) is an immune cytokine engineered to selectively promote immune responses in the tumour microenvironment. We evaluated the antitumour activity and safety of FAP-IL2v plus atezolizumab in recurrent and/o
Externí odkaz:
https://doaj.org/article/2eb15235333d4a14935f9abccb626cd2
Akademický článek
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Autor:
İrfan Çapan, Mohammed Hawash, Mohammed T. Qaoud, Levent Gülüm, Ezgi Nurdan Yenilmez Tunoglu, Kezban Uçar Çifci, Bekir Sıtkı Çevrimli, Yusuf Sert, Süleyman Servi, İrfan Koca, Yusuf Tutar
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-21 (2024)
Abstract Background Carbazole-based molecules containing thiosemicarbazide functional groups are recognized for their diverse biological activities, particularly in enhancing therapeutic anticancer effects through inhibiting crucial pathways. These d
Externí odkaz:
https://doaj.org/article/6a8568a5ddab447bad0d4fd4b16ffda5
Autor:
Matthew P. Goetz, Irfan Cicin, Laura Testa, Sara M. Tolaney, Jens Huober, Valentina Guarneri, Stephen R. D. Johnston, Miguel Martin, Priya Rastogi, Nadia Harbeck, Ashwin Shahir, Ran Wei, Valérie André, Hope S. Rugo, Joyce O’Shaughnessy
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-7 (2024)
Abstract In monarchE, adjuvant abemaciclib significantly improved invasive disease-free survival (IDFS) and distant relapse-free survival (DRFS), with sustained benefit beyond the 2-year treatment period. Abemaciclib dose reductions were allowed to p
Externí odkaz:
https://doaj.org/article/1378a75d34cd4a89ad1255e30c08bb59
Autor:
Hatice Bolek, Cagatay Arslan, Mert Basaran, İrfan Cicin, Mustafa Ozguroglu, Deniz Tural, Yüksel Ürün
Publikováno v:
JCO Global Oncology, Vol , Iss 10 (2024)
PURPOSEDurable complete response rates for metastatic renal cell carcinoma (mRCC) and metastatic bladder cancer (mBC) are low despite new therapy. Palliative care focuses on life extension and quality of life (QoL), not cure. This study aims to inves
Externí odkaz:
https://doaj.org/article/cb5cd9d0b8f74576a1727fb5374b5887
Autor:
Osman, K., Ahmet, K., Hilmi, T., İlker, N.O., Ercan, Ö., Devrim, Ç., Murat, S., Emre, Ç., İlhan, H., Mustafa, G., Yüksel, Ü., Bahiddin, Y., Cihan, E., Mehmet Ali, N. Ş., Emrah, E., Umut, D., Zeynep, O., Mehmet Ali, K., Ali, G., İvo, G., Erkan, Ö., Muhammet, B.H., Bülent, E., Selma, D., Sernaz, U., Mahmut, G., Hakan, G., İrfan, Ç.
Publikováno v:
Balkan Journal of Medical Genetics; December 2022, Vol. 25 Issue: 2 p5-14, 10p
Autor:
İrfan Çapan, Mohammed Hawash, Mohammed T. Qaoud, Levent Gülüm, Ezgi Nurdan Yenilmez Tunoglu, Kezban Uçar Çifci, Bekir Sıtkı Çevrimli, Yusuf Sert, Süleyman Servi, İrfan Koca, Yusuf Tutar
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/776e8b9b72a847ffad4f9d33f6c6464d
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 26, Iss 11, Pp 1326-1333 (2023)
Objective(s): Cadmium (CD) causes widespread and severe toxic effects on various tissues. Studies have shown that apoptosis, inflammation, and endoplasmic reticulum stress play a role in organ damage caused by CD. Phenolic compounds with strong antio
Externí odkaz:
https://doaj.org/article/81f78adef1e440c881c5abfdeb755cd6