Zobrazeno 1 - 10
of 49
pro vyhledávání: '"İlkay Küçükgüzel"'
Publikováno v:
Bangladesh Journal of Pharmacology, Vol 19, Iss 1 (2024)
In this study, new 1,3-thiazolidin-4-one derivatives containing arylmethylene groups in the 5-position were obtained from 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine (riluzole). Synthesized compounds were characterized by spectral data and elementa
Externí odkaz:
https://doaj.org/article/2c9ea7846aa143a38f72f34d78c509f4
Publikováno v:
ARKIVOC, Vol 2008, Iss 14, Pp 191-210 (2008)
Externí odkaz:
https://doaj.org/article/c8b7f57b66e14ddbb0c5ed0680c59b38
Autor:
İlkay Küçükgüzel, İlker Demirbolat, Necla Kulabaş, Merve Gürboğa, Özlem Bingöl Özakpınar, Gamze Çiftçi, Kemal Yelekçi, Jianyang Liu, Per-Johan Jakobsson, Özkan Danış, Ayşe Ogan
Publikováno v:
Organic Communications. :356-377
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa8e3c1bd2a387b1a07c84bd8cc02273
https://doi.org/10.25135/acg.oc.142.2212.2651
https://doi.org/10.25135/acg.oc.142.2212.2651
Autor:
Necla Kulabaş, İrem Set, Göknur Aktay, Şule Gürsoy, Özkan Danış, Ayşe Ogan, Safiye Sağ Erdem, Pınar Erzincan, Sinem Helvacıoğlu, Muhammed Hamitoğlu, İlkay Küçükgüzel
Today, usage of NSAIDs (nonsteroidal anti-inflammatory drugs) is very common. However, it has been proven by many studies that NSAIDs with free carboxylic acid group damage the GI (gastrointestinal) system. Our aim was to mask the acidic groups of NS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1c7c30d52eaca2b8267e036ce81ccdd
https://hdl.handle.net/11424/288894
https://hdl.handle.net/11424/288894
Publikováno v:
Structural Chemistry. 33:1157-1175
Inhibition of microsomal prostaglandin E-2 synthase-1 (mPGES-1) is promising for designing novel nonsteroidal anti-inflammatory drugs, as they lack side-effects associated with inhibition of cyclooxygenase enzymes. Azole compounds are nitrogen-contai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03406a4819c57758ad93fbddeb7d0911
https://doi.org/10.1007/s11224-022-01911-5
https://doi.org/10.1007/s11224-022-01911-5
Autor:
Necla Kulabaş, Aslı Türe, Arif Bozdeveci, Vagolu Siva Krishna, Şengül Alpay Karaoğlu, Dharmarajan Sriram, İlkay Küçükgüzel
Publikováno v:
Journal of Heterocyclic Chemistry. 59:909-926
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fd8eec947c7460c3e9ac1fc164e6605
https://doi.org/10.1002/jhet.4430
https://doi.org/10.1002/jhet.4430
Autor:
Bahadır Bülbül, Kai Ding, Chang-Guo Zhan, Gamze Çiftçi, Kemal Yelekçi, Merve Gürboğa, Özlem Bingöl Özakpınar, Esra Aydemir, Deniz Baybağ, Fikrettin Şahin, Necla Kulabaş, Sinem Helvacıoğlu, Mohammad Charehsaz, Esra Tatar, Süheyla Özbey, İlkay Küçükgüzel
Publikováno v:
Molecular Diversity.
Abstract: Some novel triazole-bearing ketone and oxime derivatives were synthesized from Ibuprofen. In vitro cytotoxic activities of all synthesized molecules against five cancer lines (human breast cancer MCF-7, human lung cancer A549, human prostat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01fff10ce342b135087a7b4b61999282
https://doi.org/10.1007/s11030-022-10551-0
https://doi.org/10.1007/s11030-022-10551-0
Publikováno v:
Journal of Research in Pharmacy. 24:801-811
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::490ec43f61102a482edea3cc7066a7db
https://doi.org/10.35333/jrp.2020.239
https://doi.org/10.35333/jrp.2020.239
Autor:
Merve Duracık, Kemal Yelekçi, Ozlem Bingol Ozakpinar, Chang-Guo Zhan, Gizem Erensoy, Ammar D. Elmezayen, Kai Ding, İlkay Küçükgüzel
Publikováno v:
Journal of Research in Pharmacy. 24:436-451
A series of new 1,3,4-oxadizole derivatives containing thioether group, has been synthesized to investigate their mPGES-1 inhibitory activities. The synthesized compounds were also evaluated for their anticancer and COX-1/2 inhibitory activities. All
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e572b70476cc8bae6f5e0b6d05b5ea60
https://doi.org/10.35333/jrp.2020.187
https://doi.org/10.35333/jrp.2020.187
Publikováno v:
Journal of Inclusion Phenomena and Macrocyclic Chemistry. 97:175-186
β-Cyclodextrin based nanosponges have been synthesized in three molar ratios, and characterized by phase solubility studies, Fourier-transform infrared spectroscopy, matrix-assisted laser desorption/ionization time of flight mass spectrometry, and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c12f577eddc71664a1a0a2117eff664
https://doi.org/10.1007/s10847-020-01003-z
https://doi.org/10.1007/s10847-020-01003-z