Zobrazeno 1 - 10
of 202
pro vyhledávání: '"İhsan Gursel"'
Autor:
Zeynep Kaya, Nevin Belder, Melike Sever-Bahcekapili, Buket Donmez-Demir, Şefik Evren Erdener, Naz Bozbeyoglu, Canan Bagci, Emine Eren-Kocak, Muge Yemisci, Hulya Karatas, Esra Erdemli, Ihsan Gursel, Turgay Dalkara
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-16 (2023)
Abstract The role of high mobility group box 1 (HMGB1) in inflammation is well characterized in the immune system and in response to tissue injury. More recently, HMGB1 was also shown to initiate an “inflammatory signaling cascade” in the brain p
Externí odkaz:
https://doaj.org/article/d89093d484494452821fd6d02092bc64
Autor:
Sibel Kalyoncu, Semiramis Yilmaz, Ayca Zeybek Kuyucu, Dogu Sayili, Olcay Mert, Hakan Soyturk, Seyda Gullu, Huseyin Akinturk, Erhan Citak, Merve Arslan, Melda Guray Taskinarda, Ibrahim Oguzhan Tarman, Gizem Yilmazer Altun, Ceren Ozer, Ridvan Orkut, Aysegul Demirtas, Idil Tilmensagir, Umur Keles, Ceren Ulker, Gizem Aralan, Yavuz Mercan, Muge Ozkan, Hasan Onur Caglar, Gizem Arik, Mehmet Can Ucar, Muzaffer Yildirim, Tugce Canavar Yildirim, Dilara Karadag, Erhan Bal, Aybike Erdogan, Serif Senturk, Serdar Uzar, Hakan Enul, Cumhur Adiay, Fahriye Sarac, Arzu Tas Ekiz, Irem Abaci, Ozge Aksoy, Hivda Ulbegi Polat, Saban Tekin, Stefan Dimitrov, Aykut Ozkul, Gerhard Wingender, Ihsan Gursel, Mehmet Ozturk, Mehmet Inan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Recombinant protein-based SARS-CoV-2 vaccines are needed to fill the vaccine equity gap. Because protein-subunit based vaccines are easier and cheaper to produce and do not require special storage/transportation conditions, they are suitable
Externí odkaz:
https://doaj.org/article/399478b705064ba69bab82d757c2112a
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 31, Iss , Pp 553-565 (2023)
Homeostatic restoration of an inflammatory response requires quenching of the immune system after pathogen threats vanish. A continued assault orchestrated by host defense results in tissue destruction or autoimmunity. A151 is the epitome of syntheti
Externí odkaz:
https://doaj.org/article/b69edf08eb7d40f583c41e62c6e26e45
Autor:
Sérgio P. Camões, Ozlem Bulut, Volkan Yazar, Maria M. Gaspar, Sandra Simões, Rita Ferreira, Rui Vitorino, Jorge M. Santos, Ihsan Gursel, Joana P. Miranda
Publikováno v:
Journal of Advanced Research, Vol 41, Iss , Pp 113-128 (2022)
Introduction: Non-healing wounds remain a major burden due to the lack of effective treatments. Mesenchymal stem cell-derived exosomes (MSC-Exo) have emerged as therapeutic options given their pro-regenerative and immunomodulatory features. Still, li
Externí odkaz:
https://doaj.org/article/dc6d07a5a377457f891f656708724ed4
Autor:
Eda Ciftci, Naz Bozbeyoglu, Ihsan Gursel, Feza Korkusuz, Feray Bakan Misirlioglu, Petek Korkusuz
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0282238 (2023)
Mesenchymal stem cell-derived exosomes regulate cell migration, proliferation, differentiation, and synthesis of the extracellular matrix, giving great potential for the treatment of different diseases. The ultracentrifugation method is the gold stan
Externí odkaz:
https://doaj.org/article/f9172965c4274ecd88ff372d451c7544
Autor:
Ismail Cem Yilmaz, Emre Dunuroglu, Ihsan Cihan Ayanoglu, Emre Mert Ipekoglu, Muzaffer Yildirim, Nogay Girginkardesler, Yusuf Ozbel, Seray Toz, Ahmet Ozbilgin, Gamze Aykut, Ihsan Gursel, Mayda Gursel
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Leishmania parasites harbor a unique network of circular DNA known as kinetoplast DNA (kDNA). The role of kDNA in leishmania infections is poorly understood. Herein, we show that kDNA delivery to the cytosol of Leishmania major infected THP-1 macroph
Externí odkaz:
https://doaj.org/article/f35325d9c25448bdafcb6b0eb9ab2509
Publikováno v:
Trakya University Journal of Natural Sciences, Vol 20, Pp 1-10 (2019)
Liver cell transplantation is a powerful alternative to orthotopic cell transplantation in the treatment of liver failures. Recently, considerable effort is being channeled to understand the nature and kinetics of directing stem cells to effectively
Externí odkaz:
https://doaj.org/article/09199396b3c947dc81f38305fdd1aa9b
Autor:
Virgil Schijns, Dragomira Majhen, Peter van der Ley, Aneesh Thakur, Artur Summerfield, Rita Berisio, Cristina Nativi, Alberto Fernández-Tejada, Carmen Alvarez-Dominguez, Sveinbjörn Gizurarson, Alla Zamyatina, Antonio Molinaro, Camillo Rosano, Žiga Jakopin, Ihsan Gursel, Siobhán McClean
Publikováno v:
Pharmaceutics, Vol 13, Iss 4, p 501 (2021)
Vaccines are the most effective medical intervention due to their continual success in preventing infections and improving mortality worldwide. Early vaccines were developed empirically however, rational design of vaccines can allow us to optimise th
Externí odkaz:
https://doaj.org/article/0249c99acc3545c8937b3a2a29d22191
Autor:
Ulku Guler, Muzaffer Yildirim, Volkan Yazar, Deniz Karakaya, Tugce Yildirim, Eda Çiftci Dede, Fehime Kara Eroglu, Ihsan Gursel, Tülin Güngör, Evra Çelikkaya, Nilsu Turay, Mehmet Bülbül, Petek Korkusuz, Bekir Salih
Publikováno v:
American Journal of Physiology: Renal Physiology
Since previous research suggests a role of a circulating factor in the pathogenesis of steroid-sensitive nephrotic syndrome (NS), we speculated that circulating plasma extracellular vesicles (EVs) are a candidate source of such a soluble mediator. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd2c6a0ff9925c73a31e95c1999caf9d
https://doi.org/10.1152/ajprenal.00097.2021
https://doi.org/10.1152/ajprenal.00097.2021
Autor:
Pelin Gülizar Ersan, Muzaffer Yildirim, Tugce Bildik, Unal Metin Tokat, Ihsan Gursel, Nilsu Turay, Tugce Yildirim, Ozgur Sahin, Bilgehan Ibibik, Irem Evcili
Publikováno v:
Immunology Letters
Tumor-derived exosomes (TEXs) could be harnessed as an immunotherapeutic cancer vaccine. These nanovesicles are inherently possesses rich tumor antigen reservoirs. Due to their undesirable features such as poor or limited immunogenicity as well as fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3877aab441c8b8954c98998994805a
https://doi.org/10.1016/j.imlet.2021.08.004
https://doi.org/10.1016/j.imlet.2021.08.004