How patients with multiple sclerosis acquire disability

Autor: Lublin, FD, Häring, DA, Ganjgahi, H, Ocampo, A, Hatami, F, Čuklina, J, Aarden, P, Dahlke, F, Arnold, DL, Wiendl, H, Chitnis, T, Nichols, TE, Kieseier, BC, Bermel, RA

Publikováno v: Brain. 145:3147-3161

Patients with multiple sclerosis acquire disability either through relapse-associated worsening (RAW) or progression independent of relapse activity (PIRA). This study addresses the relative contribution of relapses to disability worsening over the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a6af02925ed49a0dad5916596d2e2e8
https://doi.org/10.1093/brain/awac016

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Prognostic factors for worsening and improvement in multiple sclerosis using a multistate model.

Autor: Ocampo A; Novartis Pharma AG, Basel, Switzerland., Hatami F; Li Ka Shing Centre for Health Information and Discovery, Nuffield Department of Medicine, Big Data Institute, University of Oxford, Oxford, UK., Čuklina J; Novartis Pharma AG, Basel, Switzerland., Graham G; Novartis Pharma AG, Basel, Switzerland., Ganjgahi H; Li Ka Shing Centre for Health Information and Discovery, Nuffield Department of Medicine, Big Data Institute, University of Oxford, Oxford, UK.; Department of Statistics, University of Oxford, Oxford, UK., Sun Y; Li Ka Shing Centre for Health Information and Discovery, Nuffield Department of Medicine, Big Data Institute, University of Oxford, Oxford, UK., Su W; Novartis Pharmaceuticals, East Hanover, NJ, USA., Mousseau MC; Novartis Ireland Ltd, Dublin, Ireland., Gardiner S; Li Ka Shing Centre for Health Information and Discovery, Nuffield Department of Medicine, Big Data Institute, University of Oxford, Oxford, UK., Pendleton SC; Li Ka Shing Centre for Health Information and Discovery, Nuffield Department of Medicine, Big Data Institute, University of Oxford, Oxford, UK., Aarden P; Novartis Pharma AG, Basel, Switzerland., Kieseier BC; Novartis Pharma AG, Basel, Switzerland., Arnold DL; McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University, Montréal, QC, Canada., Bermel RA; Mellen Center for Multiple Sclerosis, Department of Neurology, Cleveland Clinic, Cleveland, OH, USA., Häring DA; Novartis Pharma AG, Basel, Switzerland., Nichols TE; Li Ka Shing Centre for Health Information and Discovery, Nuffield Department of Medicine, Big Data Institute, University of Oxford, Oxford, UK., Wiendl H; Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster, Germany.; Brain and Mind Centre, The University of Sydney, Sydney, NSW, Australia.

Publikováno v: Multiple sclerosis (Houndmills, Basingstoke, England) [Mult Scler] 2024 Oct; Vol. 30 (11-12), pp. 1455-1467. Date of Electronic Publication: 2024 Sep 28.