Amyloid precursor protein induces reactive astrogliosis.

Autor: Velezmoro Jauregui G; Translational Ageing and Neuroscience Program, Centre for Translational Medicine, International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic.; Department of Biology, Faculty of Medicine, Masaryk University, Brno, Czech Republic., Vukić D; Central European Institute of Technology, Masaryk University, Brno, Czech Republic.; Faculty of Science, National Centre for Biomedical Research, Masaryk University, Brno, Czech Republic., Onyango IG; Translational Ageing and Neuroscience Program, Centre for Translational Medicine, International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic., Arias C; Department of Neurosciences, University of California San Diego, La Jolla, California, USA., Novotný JS; Faculty of Medicine and Dentistry, Institute of Molecular and Translational Medicine, Palacky University Olomouc, Olomouc, Czech Republic., Texlová K; Translational Ageing and Neuroscience Program, Centre for Translational Medicine, International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic., Wang S; Veterans Affairs San Diego Healthcare System, San Diego, USA.; Department of Anesthesia, University of California San Diego, La Jolla, California, USA., Kovačovicova KL; PsychoGenics, Paramus, New Jersey, USA., Polakova N; Faculty of Medicine and Dentistry, Institute of Molecular and Translational Medicine, Palacky University Olomouc, Olomouc, Czech Republic., Zelinkova J; Faculty of Medicine and Dentistry, Institute of Molecular and Translational Medicine, Palacky University Olomouc, Olomouc, Czech Republic., Čarna M; Faculty of Medicine and Dentistry, Institute of Molecular and Translational Medicine, Palacky University Olomouc, Olomouc, Czech Republic., Lacovich V; Central European Institute of Technology, Masaryk University, Brno, Czech Republic., Head BP; Veterans Affairs San Diego Healthcare System, San Diego, USA.; Department of Anesthesia, University of California San Diego, La Jolla, California, USA., Havas D; PsychoGenics, Paramus, New Jersey, USA., Mistrik M; Faculty of Medicine and Dentistry, Institute of Molecular and Translational Medicine, Palacky University Olomouc, Olomouc, Czech Republic., Zorec R; Laboratory of Neuroendocrinology, Molecular Cell Physiology, Faculty of Medicine, Institute of Pathophysiology, University of Ljubljana, Ljubljana, Slovenia.; Celica Biomedical, Technology Park, Ljubljana, Slovenia., Verkhratsky A; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.; Achucarro Centre for Neuroscience, IIKERBASQUE, Basque Foundation for Science, Bilbao, Spain.; Department of Stem Cell Biology, State Research Institute Centre for Innovative Medicine, Vilnius, Lithuania.; Department of Forensic Analytical Toxicology, School of Forensic Medicine, China Medical University, Shenyang, Liaoning Province, China., Keegan L; Central European Institute of Technology, Masaryk University, Brno, Czech Republic., O'Connell MA; Central European Institute of Technology, Masaryk University, Brno, Czech Republic., Rissman R; Department of Neurosciences, University of California San Diego, La Jolla, California, USA., Stokin GB; Translational Ageing and Neuroscience Program, Centre for Translational Medicine, International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic.; Faculty of Medicine and Dentistry, Institute of Molecular and Translational Medicine, Palacky University Olomouc, Olomouc, Czech Republic.; Department of Neurology, Gloucestershire Royal Hospital, Gloucestershire NHS Foundation Trust, Gloucester, UK.

Publikováno v: Acta physiologica (Oxford, England) [Acta Physiol (Oxf)] 2024 Jun; Vol. 240 (6), pp. e14142. Date of Electronic Publication: 2024 Apr 08.

Pathogenesis of Alzheimer's disease: Involvement of the choroid plexus.

Autor: Čarna M; International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic., Onyango IG; International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic., Katina S; International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic.; Institute of Mathematics and Statistics, Masaryk University, Brno, Czech Republic., Holub D; Institute for Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic., Novotny JS; International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic., Nezvedova M; RECETOX Centre, Faculty of Sciences, Masaryk University, Brno, Czech Republic., Jha D; RECETOX Centre, Faculty of Sciences, Masaryk University, Brno, Czech Republic., Nedelska Z; International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic.; Memory Clinic, Department of Neurology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic., Lacovich V; International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic., Vyvere TV; Icometrix, Leuven, Belgium., Houbrechts R; Icometrix, Leuven, Belgium., Garcia-Mansfield K; Collaborative Center for Translational Mass Spectrometry, Translational Genomics Research Institute, Phoenix, Arizona, USA., Sharma R; Collaborative Center for Translational Mass Spectrometry, Translational Genomics Research Institute, Phoenix, Arizona, USA., David-Dirgo V; Collaborative Center for Translational Mass Spectrometry, Translational Genomics Research Institute, Phoenix, Arizona, USA., Vyhnalek M; International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic.; Memory Clinic, Department of Neurology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic., Texlova K; International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic., Chaves H; FLENI, Buenos Aires, Argentina., Bakkar N; Department of Neurobiology, Barrow Neurological Institute, Phoenix, Arizona, USA., Pertierra L; FLENI, Buenos Aires, Argentina., Vinkler M; Institute of Mathematics and Statistics, Masaryk University, Brno, Czech Republic., Markova H; International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic.; Memory Clinic, Department of Neurology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic., Laczo J; International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic.; Memory Clinic, Department of Neurology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic., Sheardova K; International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic.; 1st Department of Neurology, St. Anne's University Hospital and Faculty of Medicine, Masaryk University, Brno, Czech Republic., Hortova-Kohoutkova M; International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic., Frič J; International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic.; Institute of Hematology and Blood Transfusion, Prague, Czech Republic., Forte G; International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic., Kaňovsky P; Department of Neurology, Faculty of Medicine and Dentistry, Palacky University Olomouc and Research and Science Department, University Hospital Olomouc, Olomouc, Czech Republic., Belaškova S; International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic., Damborsky J; International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic.; RECETOX Centre, Faculty of Sciences, Masaryk University, Brno, Czech Republic., Hort J; International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic.; Memory Clinic, Department of Neurology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic., Seyfried NT; Center for Neurodegenerative Disease, Emory University School of Medicine, Atlanta, Georgia, USA.; Goizueta Alzheimer's Disease Research Center, Emory University, Atlanta, Georgia, USA.; Departments of Bioachemistry and Neurology, Emory University School of Medicine, Atlanta, Georgia, USA., Bowser R; Department of Neurobiology, Barrow Neurological Institute, Phoenix, Arizona, USA., Sevlever G; FLENI, Buenos Aires, Argentina., Rissman RA; Department of Neurosciences, University of California San Diego, La Jolla, California, USA., Smith RA; Center for Neurologic Study, La Jolla, California, USA., Hajduch M; Institute for Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic., Pirrotte P; Collaborative Center for Translational Mass Spectrometry, Translational Genomics Research Institute, Phoenix, Arizona, USA.; Mass Spectrometry & Proteomics Core Facility, City of Hope Comprehensive Cancer Center, Duarte, California, USA., Spacil Z; RECETOX Centre, Faculty of Sciences, Masaryk University, Brno, Czech Republic., Dammer EB; Center for Neurodegenerative Disease, Emory University School of Medicine, Atlanta, Georgia, USA.; Goizueta Alzheimer's Disease Research Center, Emory University, Atlanta, Georgia, USA., Limbäck-Stokin C; Department of Cellular Pathology, Imperial College Healthcare NHS Trust, London, UK.; Imperial College London, Faculty of Medicine, London, UK., Stokin GB; International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic.; Division of Neurology, University Medical Centre, Ljubljana, Slovenia.; Translational Aging and Neuroscience Program, Mayo Clinic, Rochester, Minnesota, USA.

Publikováno v: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2023 Aug; Vol. 19 (8), pp. 3537-3554. Date of Electronic Publication: 2023 Feb 24.

Unraveling axonal mechanisms of traumatic brain injury.

Autor: Pozo Devoto VM; Translational Neuroscience and Ageing Program, Centre for Translational Medicine, International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic., Lacovich V; Translational Neuroscience and Ageing Program, Centre for Translational Medicine, International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic., Feole M; Translational Neuroscience and Ageing Program, Centre for Translational Medicine, International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic., Bhat P; Translational Neuroscience and Ageing Program, Centre for Translational Medicine, International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic., Chovan J; Biostatistics Department, International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic., Čarna M; Translational Neuroscience and Ageing Program, Centre for Translational Medicine, International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic., Onyango IG; Translational Neuroscience and Ageing Program, Centre for Translational Medicine, International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic., Dragišić N; Translational Neuroscience and Ageing Program, Centre for Translational Medicine, International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic., Sűsserová M; Translational Neuroscience and Ageing Program, Centre for Translational Medicine, International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic., Barrios-Llerena ME; Proteomics and Mass Spectrometry Core Lab, International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic., Stokin GB; Translational Neuroscience and Ageing Program, Centre for Translational Medicine, International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic. gbstokin@alumni.ucsd.edu.; Division of Neurology, University Medical Centre, Ljubljana, Slovenia. gbstokin@alumni.ucsd.edu.; Department of Neurosciences, Mayo Clinic, Rochester, MN, USA. gbstokin@alumni.ucsd.edu.

Publikováno v: Acta neuropathologica communications [Acta Neuropathol Commun] 2022 Sep 21; Vol. 10 (1), pp. 140. Date of Electronic Publication: 2022 Sep 21.

Choice of blood collection methods influences extracellular vesicles counts and miRNA profiling.

Autor: Tran, Vivian¹ (AUTHOR), Oliveira‐Jr, Getulio Pereira de^2,3 (AUTHOR), Chidester, Stephanie⁴ (AUTHOR), Lu, Shulin² (AUTHOR), Pleet, Michelle L.⁵ (AUTHOR), Ivanov, Alexander R.³ (AUTHOR), Tigges, John⁶ (AUTHOR), Yang, Moua⁷ (AUTHOR), Jacobson, Steven⁵ (AUTHOR), Gonçalves, Maria C. B.¹ (AUTHOR), Schmaier, Alec A.^7,8 (AUTHOR), Jones, Jennifer⁴ (AUTHOR), Ghiran, Ionita C.¹ (AUTHOR) ighiran@bidmc.harvard.edu

Publikováno v: Journal of Extracellular Biology. Oct2024, Vol. 3 Issue 10, p1-19. 19p.

Choroid plexus volumes and auditory verbal learning scores are associated with conversion from mild cognitive impairment to Alzheimer's disease.

Autor: Pearson, Michael J.¹ (AUTHOR), Wagstaff, Ruth¹ (AUTHOR), Williams, Rebecca J.¹ (AUTHOR) rebecca.williams@cdu.edu.au

Publikováno v: Brain & Behavior. Jul2024, Vol. 14 Issue 7, p1-12. 12p.