Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Čadež, Tena"'
Autor:
Mlakić, Milena1 (AUTHOR) mdragojev@fkit.unizg.hr, Čadež, Tena2 (AUTHOR) tcadez@imi.hr, Šinko, Goran2 (AUTHOR) gsinko@imi.hr, Škorić, Irena1 (AUTHOR) iskoric@fkit.unizg.hr, Kovarik, Zrinka2,3 (AUTHOR) iskoric@fkit.unizg.hr
Publikováno v:
Biomolecules (2218-273X). Jun2024, Vol. 14 Issue 6, p679. 37p.
Autor:
Čadež, Tena1 (AUTHOR), Kolić, Dora1 (AUTHOR), Šinko, Goran1 (AUTHOR), Kovarik, Zrinka1 (AUTHOR) zkovarik@imi.hr
Publikováno v:
Scientific Reports. 11/2/2021, Vol. 11 Issue 1, p1-11. 11p.
The main action mechanism of organophosphorus compounds (OP) is the inhibition of acetylcholinesterase (AChE) that causes the accumulation of the neurotransmitter acetylcholine and excessive stimulation of nicotinic and muscarinic receptors in the ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::189ec27e2a3dbf69e176275876e298d5
https://www.bib.irb.hr/1271056
https://www.bib.irb.hr/1271056
Autor:
Čadež, Tena
Sposobnost butirilkolinesteraze (BChE) da vezanjem organofosfornih (OP) spojeva snižava njihovu koncentraciju u organizmu i time sprječava inhibiciju acetilkolinesteraze (AChE) predstavlja novi temelj terapije kod otrovanja ovim spojevima. Budući
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3908::2ec6f889b383955f845980c6388bdb49
https://repozitorij.pmf.unizg.hr/islandora/object/pmf:11494/datastream/PDF
https://repozitorij.pmf.unizg.hr/islandora/object/pmf:11494/datastream/PDF
The phosphylation of acetylcholinesterase (AChE), a pivotal enzyme in hydrolysis of the neurotransmitter acetylcholine, by nerve agents (NAs) still has no adequate or fully efficient medical countermeasures. Furthermore, oxime antidotes known for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::8f52f8944042839ff6ab986e536ef601
https://doi.org/10.1111/jnc.15674
https://doi.org/10.1111/jnc.15674
Toxicity of organophosphorus compounds remains a major public health concern due to their widespread use as pesticides and the existence of nerve agents. Their common mechanism of action involves inhibition of enzymes acetylcholinesterase (AChE) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::90ecbcf676266dbc10d9047c3a1f5609
https://www.bib.irb.hr/1194793
https://www.bib.irb.hr/1194793
Nerve agents’ (NA) neurotoxicity is primarily induced by phos-phorylation of acetylcholinesterase (AChE), the key enzyme inthe neurotransmitter acetylcholine (ACh) pathway. Its akinenzyme, butyrylcholinesterase (BChE), an enzyme without knownessent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::a8a078ab7c1208d2ac324770ac58025b
https://doi.org/10.1002/2211-5463.13440
https://doi.org/10.1002/2211-5463.13440
Autor:
Čadež, Tena, Kovarik, Zrinka
The covalent inhibition of cholinesterases (ChE) with organophosphates (OPs) requires immediate treatment mostly based on oximes as reactivators of acetylcholinesterase (AChE). A downfall of this well-known treatment is its inapplicability for the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::3e62b4b8004ee768306ebde53b25bd41
https://www.bib.irb.hr/1194702
https://www.bib.irb.hr/1194702
Autor:
Kovarik, Zrinka, Pehar, Vesna, Čadež, Tena, Kolić, Dora, Zandona, Antonio, Lulić, Ana-Marija, Šinko, Goran, Katalinić, Maja
The toxicity of organophosphorus compounds (OPs) remains a major public health concern due to their widespread use as pesticides and herbicides. Their common mechanism of action involves the inhibition of enzymes acetylcholinesterase (AChE) and butyr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::87aa5eb955ff9fda26503e534ffb8bd0
https://www.bib.irb.hr/1214584
https://www.bib.irb.hr/1214584
The inhibition of AChE and BChE by organophosphates (OPs) as nerve agents and pesticides compromises normal cholinergic nerve signal transduction in the peripheral and central nervous systems (CNS) leading to cholinergic crisis. The treatment compris
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::db64627a949f310cf57b20ff3b37cdf5
https://www.bib.irb.hr/1195102
https://www.bib.irb.hr/1195102