Adaptive Plasticity in the Hippocampus of Young Mice Intermittently Exposed to MDMA Could Be the Origin of Memory Deficits

Autor: Jorge Camarasa, Elena Escubedo, David Pubill, Sonia Abad, Antoni Camins

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Europe PubMed Central
Recercat. Dipósit de la Recerca de Catalunya
instname

(±)3,4-Methylenedioxymethamphetamine (MDMA) is a relatively selective dopaminergic neurotoxin in mice. This study was designed to evaluate whether MDMA exposure affects their recognition memory and hippocampal expression of plasticity markers. Mice

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::761d50b8b61be64ba3d5cef133d06e5e
https://doi.org/10.1007/s12035-015-9618-z

Use of MDMA in the treatment of Post-traumatic Stress Disorder

Autor: Molina Trullàs, Júlia

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona

Treballs Finals de Grau de Farmàcia, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona, 2018. Tutor: David Pubill.
[eng] 3,4-methylenedioxy-N-methylamphetamine (MDMA; also known as "ecstasy") is a psychoactive drug t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::40b5df06c098b88e5aa10b726644024e
http://hdl.handle.net/2445/125013

Contribution to the study of the mechanisms of action and neuropsychopharmacological effects of MDMA and new β-ketoamphetamines

Autor: Ciudad Roberts, Andrés

Publikováno v: TDX (Tesis Doctorals en Xarxa)
TDR. Tesis Doctorales en Red
instname
Dipòsit Digital de la UB
Universidad de Barcelona

Drugs of abuse are a matter of great concern, as their use is widespread in all stratums of society, and can entail both acute and long-term negative consequences. For this reason, our research group is devoted to investigating the mechanisms underly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5a19d571b611ee8a43383aa97450f009
http://hdl.handle.net/2445/98022

Molecular basis of the selective binding of MDMA enantiomers to the Alpha4Beta2 nicotinic receptor subtype: synthesis, pharmacological evaluation and mechanistic studies

Autor: Sara Garcia-Ratés, Antoni Riera, Salomé Llabrés, Jorge Camarasa, José I. Borrell, David Pubill, Elena Escubedo, Edgar Cristóbal-Lecina, F. Javier Luque

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
instname
RECERCAT (Dipòsit de la Recerca de Catalunya)
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)

The α4β2 nicotinic acetylcholine receptor (nAChR) is a molecular target of 3,4-methylenedioxymethamphetamine (MDMA), a synthetic drug also known as ecstasy, and it modulates the MDMA-mediated reinforcing properties. However, the enantioselective pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8cf27628087816c4487370a076d4ac9
http://hdl.handle.net/2445/111900

3,4-Methylenedioxy-methamphetamine induces in vivo regional up-regulation of central nicotinic receptors in rats and potentiates the regulatory effects of nicotine on these receptors

Autor: Sara Garcia-Ratés, David Pubill, Elena Escubedo, Jordi Camarasa

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname

Nicotine (NIC), the main psychostimulant compound of smoked tobacco, exerts its effects through activation of central nicotinic acetylcholine receptors (nAChR), which become up-regulated after chronic administration. Recent work has demonstrated that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26b9a92218793f7da67aafad44571215
http://hdl.handle.net/2445/43395