Endoplasmic reticulum stress produced by Thapsigargin affects the occurrence of spike-wave discharge by modulating unfolded protein response pathways and activating immune responses in a dose-dependent manner.

Autor: Karadenizli Taşkin S; Physiology Department, Kocaeli University Medical Faculty, Kocaeli, Turkey. Electronic address: skaradenizli@kocaeli.edu.tr., Şahin D; Physiology Department, Kocaeli University Medical Faculty, Kocaeli, Turkey. Electronic address: sahindeniztr@yahoo.com., Dede F; Physiology Department, Kocaeli University Medical Faculty, Kocaeli, Turkey. Electronic address: fzltdd.08@gmail.com., Ünal Halbutoğullari ZS; Stem Cell and Gene Therapy Research and Application Center, Kocaeli University, Kocaeli, Turkey. Electronic address: zehraseda@gmail.com., Sarihan M; Department of Medical Biology/Proteomics Laboratory, Kocaeli University Medical Faculty, Kocaeli, Turkey. Electronic address: mbgsarihan@hotmail.com., Kurnaz Özbek S; Department of Histology and Embryology, Kocaeli University Medical Faculty, Kocaeli, Turkey. Electronic address: semakurnaz85@gmail.com., Özsoy ÖD; Department of Biochemistry, Kocaeli University Medical Faculty, Kocaeli, Turkey. Electronic address: doga83@hotmail.com., Kasap M; Department of Medical Biology/Proteomics Laboratory, Kocaeli University Medical Faculty, Kocaeli, Turkey. Electronic address: mkasap2008@gmail.com., Yazir Y; Stem Cell and Gene Therapy Research and Application Center, Kocaeli University, Kocaeli, Turkey; Department of Histology and Embryology, Kocaeli University Medical Faculty, Kocaeli, Turkey. Electronic address: yusufhanyazir@yahoo.com., Ateş N; Physiology Department, Kocaeli University Medical Faculty, Kocaeli, Turkey. Electronic address: nates@kocaeli.edu.tr.

Publikováno v: European journal of pharmacology [Eur J Pharmacol] 2024 Jul 05; Vol. 974, pp. 176613. Date of Electronic Publication: 2024 Apr 25.