Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ümit Mert"'
Autor:
Rald V. M. Groven, Christel Kuik, Johannes Greven, Ümit Mert, Freek G. Bouwman, Martijn Poeze, Taco J. Blokhuis, Markus Huber-Lang, Frank Hildebrand, Berta Cillero-Pastor, Martijn van Griensven
Publikováno v:
Bone & Joint Research, Vol 13, Iss 5, Pp 214-225 (2024)
Aims: The aim of this study was to determine the fracture haematoma (fxH) proteome after multiple trauma using label-free proteomics, comparing two different fracture treatment strategies. Methods: A porcine multiple trauma model was used in which tw
Externí odkaz:
https://doaj.org/article/573a6f6a87ed43d9be6fe17da2e0373b
Autor:
Nan Zhou, Rald V. M. Groven, Klemens Horst, Ümit Mert, Johannes Greven, Tom Eirik Mollnes, Markus Huber-Lang, Martijn van Griensven, Frank Hildebrand, Elizabeth R. Balmayor
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundRespiratory failure can be a severe complication after polytrauma. Extensive systemic inflammation due to surgical interventions, as well as exacerbated post-traumatic immune responses influence the occurrence and progression of respiratory
Externí odkaz:
https://doaj.org/article/7684696c74d540418c2efae014825520
Autor:
Bingduo Wang, Aliona Wöhler, Johannes Greven, Rebekka J. S. Salzmann, Cindy M. Keller, Tobias Tertel, Qun Zhao, Ümit Mert, Klemens Horst, Ludmila Lupu, Markus Huber-Lang, Martijn van Griensven, Tom Erik Mollnes, Sebastian Schaaf, Robert Schwab, Christian P. Strassburg, Ingo G. H. Schmidt-Wolf, Bernd Giebel, Frank Hildebrand, Veronika Lukacs-Kornek, Arnulf G. Willms, Miroslaw T. Kornek
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundDespite major advances in medicine, blood-borne biomarkers are urgently needed to support decision-making, including polytrauma. Here, we assessed serum-derived extracellular vesicles (EVs) as potential markers of decision-making in polytra
Externí odkaz:
https://doaj.org/article/3b8ca466e5ec44dabab96e095d62f58f
Autor:
Qun Zhao, Xing Zhang, You Li, Zhizhen He, Kang Qin, Eva Miriam Buhl, Ümit Mert, Klemens Horst, Frank Hildebrand, Elizabeth R. Balmayor, Johannes Greven
Publikováno v:
Pharmaceutics, Vol 16, Iss 2, p 279 (2024)
Objective: Existing research suggests that bone marrow-derived mesenchymal stem cells (BMSCs) may promote endogenous bone repair. This may be through the secretion of factors that stimulate repair processes or directly through differentiation into os
Externí odkaz:
https://doaj.org/article/70ea599175a7497cbf6f3a106a566a73
Autor:
Rald Victor Maria Groven, Johannes Greven, Ümit Mert, Klemens Horst, Qun Zhao, Taco Johan Blokhuis, Markus Huber-Lang, Frank Hildebrand, Martijn van Griensven
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionTwo trauma treatment principles are Early Total Care (ETC), and Damage Control Orthopedics (DCO). Cellular mechanisms that underlie the connection between treatment type, its systemic effects, and tissue regeneration are not fully known.
Externí odkaz:
https://doaj.org/article/670456bd62f44b06b06b868ff284ae21
Autor:
Ludmila Lupu, Klemens Horst, Johannes Greven, Ümit Mert, Judith A.K. Ludviksen, Kristin Pettersen, Corinna Lau, Yang Li, Annette Palmer, Kang Qin, Xing Zhang, Benjamin Mayer, Martijn van Griensven, Markus Huber-Lang, Frank Hildebrand, Tom Eirik Mollnes
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Dysfunctional complement activation and Toll-like receptor signaling immediately after trauma are associated with development of trauma-induced coagulopathy and multiple organ dysfunction syndrome. We assessed the efficacy of the combined inhibition
Externí odkaz:
https://doaj.org/article/94889c1af8634422aecff717f0fb86a1
Autor:
Johannes Greven, Klemens Horst, Zhi Qiao, Felix Marius Bläsius, Ümit Mert, Michel Paul Johan Teuben, Nils Hendrik Becker, Roman Pfeifer, Hans-Christoph Pape, Frank Hildebrand
Publikováno v:
European Journal of Medical Research, Vol 25, Iss 1, Pp 1-10 (2020)
Abstract Background In the stabilization of femoral fractures in mono- and polytrauma, clinical practice has shown better care through intramedullary nailing. However, the reason why this is the case is not fully understood. In addition to concomitan
Externí odkaz:
https://doaj.org/article/ed543ae4e8ae40bc86b2c70d05765f78
Contemporary deep learning models have demonstrated promising results across various applications within seismology and earthquake engineering. These models rely primarily on utilizing ground motion records for tasks such as earthquake event classifi
Externí odkaz:
http://arxiv.org/abs/2403.07569
Endoscopic imaging is commonly used to diagnose Ulcerative Colitis (UC) and classify its severity. It has been shown that deep learning based methods are effective in automated analysis of these images and can potentially be used to aid medical docto
Externí odkaz:
http://arxiv.org/abs/2311.06057
Autor:
Klemens Horst, Rachel Lentzen, Martin Tonglet, Ümit Mert, Philipp Lichte, Christian D. Weber, Philipp Kobbe, Nicole Heussen, Frank Hildebrand
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 4, p 945 (2020)
The modified Trauma-Induced Coagulopathy Clinical Score (mTICCS) presents a new scoring system for the early detection of the need for a massive transfusion (MT). While validated in a large trauma cohort, the comparison of mTICCS to established scori
Externí odkaz:
https://doaj.org/article/c179a9fa26b0438899487777d8d1d14c