Výsledky vyhledávání - "Ümit M. Koçyiğit"

Determination of biological studies and molecular docking calculations of isatin-thiosemicarbazone hybrid compounds

Autor: Ümit M. Koçyiğit, Murat Doğan, Halit Muğlu, Parham Taslimi, Burak Tüzün, Hasan Yakan, Halil Bal, Emre Güzel, İlham Gülçin

Publikováno v: JOURNAL OF MOLECULAR STRUCTURE

Design, synthesis, structural elucidation, and investigation of cytotoxic and antimicrobial activity, butyrylcholinesterase (BChE), and acetylcholinesterase (AChE) enzyme inhibition effects of isatinthiosemicarbazone hybrid compounds (1–15) are rep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f96f43ca7113136d0f7332412c18676
https://hdl.handle.net/20.500.12418/13878

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Composition characterization and biological activity study of achillea vermicularis extract and extract-loaded nanoparticles

Autor: Murat Doğan, Ümit M. Koçyiğit, Feyza Nur Çetin, Beyza Nur Yılmaz, Turgut Taşkın

© 2023 International Union of Biochemistry and Molecular Biology, Inc.Antiproliferative activity of Achillea vermicularis extracts was calculated on glial (C6) and keratinocyte (HaCaT) cell lines using XTT assay. It was observed that all extracts of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196572c917132062e88b01726e3c30e7
https://hdl.handle.net/11424/285761

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Synthesis and biological evaluation of thiosemicarbazone derivatives

Autor: Meliha Burcu Gürdere, Murat Doğan, Ümit M. Koçyiğit, Mustafa Ceylan, Yakup Budak

Publikováno v: Medical Oncology. 39

In this study, firstly, 22 thiosemicarbazone derivatives (3a-y) were synthesized. Then, ADME parameters, pharmacokinetic properties, drug-like structures, and suitability for medicinal chemistry of these molecules were studied theoretically by using

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c84f6c1ad0209e3a804dc1ca3970369
https://doi.org/10.1007/s12032-022-01784-y

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Potential thiosemicarbazone‐based enzyme inhibitors: Assessment of antiproliferative activity, metabolic enzyme inhibition properties, and molecular docking calculations

Autor: Hasan Yakan, Ümit M. Koçyiğit, Halit Muğlu, Mustafa Ergul, Sultan Erkan, Emre Güzel, Parham Taslimi, İlhami Gülçin

Publikováno v: JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

A new series of thiosemicarbazone derivatives (1–11) were prepared from various aldehydes and isocyanates with high yields and practical methods. The structures of these compounds were elucidated by Fourier transform infrared, 1H‐nuclear magnetic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f367e4b387898c8fe68b3f32f8cd17fc
https://doi.org/10.1002/jbt.23018

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Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular docking studies of new imidazolyl hydrazone derivatives

Autor: Michael Tapera, Hüseyin Kekeçmuhammed, Burak Tüzün, Emin Sarıpınar, Ümit M. Koçyiğit, Ebrar Yıldırım, Murat Doğan, Yunus Zorlu

Publikováno v: Journal of Molecular Structure. 1269:133816

© 2022 Elsevier B.V.A new series of imidazolyl hydrazone derivatives IA (1-12) were prepared from a condensation reaction between indoline-2,3-dione (isatin) and 2-benzylidenehydrazinecarboximidamide derivatives. The structure of compounds was eluci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77d816f607373bbccf79f584f115bed8
https://doi.org/10.1016/j.molstruc.2022.133816

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