Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ülkü Güler"'
Autor:
Amir Ata Saei, Christian Michel Beusch, Alexey Chernobrovkin, Pierre Sabatier, Bo Zhang, Ülkü Güler Tokat, Eleni Stergiou, Massimiliano Gaetani, Ákos Végvári, Roman A. Zubarev
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Anticancer drugs often have widespread effects on the cellular proteome. Here, the authors generate a proteome signature library of drug-treated cancer cell lines and develop a software tool to deconvolute drug targets and gain insights into their me
Externí odkaz:
https://doaj.org/article/ad0814e6df26497b89b780d2b504f842
Autor:
Aslı Erdem Yayayürük, Selim Girgin, Serkan Vuruk, Ülkü Güler, Melike Güngör, Halil İbrahim Bostancı, Serap Annette Akgür
Publikováno v:
Adli Tıp Bülteni, Vol 21, Iss 1 (2016)
Amaç: Günümüzde kötüye kullanılan yasadışı maddeler arasında en yaygın kullanılan madde esrardır. Esrarın saptanmasına yönelik yapılan çalışmalarda, idrarda ana metaboliti olan THC-COOH’un kat-faz (SPE) ve sıvı-faz (ELE) ekst
Externí odkaz:
https://doaj.org/article/dbeeefb396d44bf5b017da9c7c0adb08
Autor:
Saei, Amir Ata ‡, Sabatier, Pierre ‡, Tokat, Ülkü Güler ‡, Chernobrovkin, Alexey ‡, Pirmoradian, Mohammad ‡, Zubarev, Roman A. ‡, §
Publikováno v:
In Molecular & Cellular Proteomics June 2018 17(6):1144-1155
Publikováno v:
Molecular omics.
Many cells are known to actively release nano-sized outer membrane vesicles (OMVs) that contain bioactive proteins, lipids, and nucleic acids into the extracellular environment. These vesicles have been associated with adaptation to environmental str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c646e2837ece93b28ef518a95ce3b219
https://pubmed.ncbi.nlm.nih.gov/36597842
https://pubmed.ncbi.nlm.nih.gov/36597842
Autor:
Haci Mehmet Kayili, Nazire Barlas, Deniz Baran Demirhan, Mehmet Emrah Yaman, Mehmet Atakay, Ülkü Güler, Mustafa Kara, Kadir Serafettin Tekgunduz, Bekir Salih
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::910b9e8f8b2c2a891d3fe293e3bb7cb0
https://doi.org/10.2139/ssrn.4330998
https://doi.org/10.2139/ssrn.4330998
Autor:
Haci Mehmet Kayili, Nazire Barlas, Deniz Baran Demirhan, Mehmet Emrah Yaman, Mehmet Atakay, Ülkü Güler, Mustafa Kara, Kadir Serafettin Tekgunduz, Bekir Salih
Publikováno v:
Food Chemistry. 421:136166
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79994ea463afa9dbdf5fc59e33a41a9e
https://doi.org/10.1016/j.foodchem.2023.136166
https://doi.org/10.1016/j.foodchem.2023.136166
Autor:
Roman A. Zubarev, Amir Ata Saei, Christian M. Beusch, Bo Zhang, Ülkü Güler Tokat, Alexey Chernobrovkin, Pierre Sabatier, Eleni Stergiou, Ákos Végvári, Massimiliano Gaetani
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Deconvolution of targets and action mechanisms of anticancer compounds is fundamental in drug development. Here, we report on ProTargetMiner as a publicly available expandable proteome signature library of anticancer molecules in cancer cell lines. B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5662033eea53ba0eb95dc324ca391eb0
https://pubmed.ncbi.nlm.nih.gov/31844049
https://pubmed.ncbi.nlm.nih.gov/31844049
Autor:
Roman A. Zubarev, Ülkü Güler Tokat, Massimiliano Gaetani, Christian M. Beusch, Alexey Chernobrovkin, Amir Ata Saei, Ákos Végvári, Pierre Sabatier, Bo Zhang
We present a publicly available, expandable proteome signature library of anticancer molecules in A549 adenocarcinoma cells. Based on 287 proteomes affected by 56 drugs, the main dataset contains 7,328 proteins and 1,307,859 refined protein-drug pair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f66caa2dbaef9ae8cdecbd1ba0766ac
Autor:
Ülkü Güler Tokat, Pierre Sabatier, Alexey Chernobrovkin, Mohammad Pirmoradian, Amir Ata Saei, Roman A. Zubarev
Publikováno v:
Molecularcellular proteomics : MCP. 17(6)
Chemotherapeutics cause the detachment and death of adherent cancer cells. When studying the proteome changes to determine the protein target and mechanism of action of anticancer drugs, the still-attached cells are normally used, whereas the detache
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::221422591623a5572ac787a629942b1c
https://pubmed.ncbi.nlm.nih.gov/29572246
https://pubmed.ncbi.nlm.nih.gov/29572246