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pro vyhledávání: '"Øyvind Dahle"'
Autor:
Michael R. Kuehn, Øyvind Dahle
Publikováno v:
Developmental Dynamics. 245:807-815
Background Pluripotent embryonic stem cells (ESCs) offer great potential for regenerative medicine. However, efficient in vitro generation of specific desired cell types is still a challenge. We previously established that Smad2/3 signaling, essentia
Autor:
Michael R. Kuehn, Øyvind Dahle
Publikováno v:
Stem Cells. 31:1488-1497
Integration of extrinsic signals, epigenetic regulators, and intrinsic transcription factors establishes pluripotent stem cell identity. Interplay between these components also underlies the capacity of stem cells to undergo differentiation, and of d
Autor:
Øyvind, Dahle, Michael R, Kuehn
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 245(7)
Pluripotent embryonic stem cells (ESCs) offer great potential for regenerative medicine. However, efficient in vitro generation of specific desired cell types is still a challenge. We previously established that Smad2/3 signaling, essential for endod
Publikováno v:
Experimental Cell Research. 297:118-126
The c-Myb transcription factor plays a central role in the regulation of cell growth and differentiation of hematopoietic cells. Being the product of a proto-oncogene, one would expect c-Myb function to be modulated by signal transduction pathways, b
Autor:
Tor Øyvind Andersen, Vilborg Matre, Giannino Del Sal, Øyvind Dahle, Oddmund Nordgård, Odd S. Gabrielsen
Publikováno v:
European Journal of Biochemistry. 270:1338-1348
The transcription factor v-Myb is a potent inducer of myeloid leukemias, and its cellular homologue c-Myb plays a crucial role in the regulation of hematopoiesis. Recently, Bies and coworkers (Bies, J., Markus, J. & Wolff, L. (2002) J. Biol. Chem, 27
Publikováno v:
Biochimie. 83:969-971
The Jun activation domain binding protein 1 (JAB1) was first identified as an interaction partner and coactivator of c-Jun. Subsequently, it was found to be a subunit of the COP9 signalosome (CSN) and termed CSN subunit 5 (CSN5). This complex regulat
Publikováno v:
Science Signaling. 3
Both intercellular signaling and epigenetic mechanisms regulate embryonic development, but it is unclear how they are integrated to establish and maintain lineage-specific gene expression programs. Here, we show that a key function of the development
Autor:
Marit Ledsaak, Thomas Sæther, Øyvind Dahle, Odd S. Gabrielsen, Vilborg Matre, Anne Hege Alm-Kristiansen, Tone Berge, Florence Aubry
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, 2007, 282 (19), pp.13994-4005. ⟨10.1074/jbc.M700755200⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2007, 282 (19), pp.13994-4005. ⟨10.1074/jbc.M700755200⟩
Journal of Biological Chemistry, 2007, 282 (19), pp.13994-4005. ⟨10.1074/jbc.M700755200⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2007, 282 (19), pp.13994-4005. ⟨10.1074/jbc.M700755200⟩
International audience; The c-Myb protein belongs to a group of early hematopoietic transcription factors that are important for progenitor generation and proliferation. These factors have been hypothesized to participate in establishing chromatin pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b41fd706a32f6c73724f06f67ebb421
https://hal.science/hal-00653245
https://hal.science/hal-00653245
Publikováno v:
Blood. 105(3)
Interferon (IFN) induces expression of proapoptotic genes and has been used in the clinical treatment of multiple myeloma. The promyelocytic leukemia (PML) gene is an IFN-induced target that encodes a tumor suppressor protein. PML protein is typicall