Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Øystein Spydevold"'
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 4, Pp 744-754 (1998)
This work describes the molecular mechanisms of fatty acid and hormonal modulations of the retinoid X receptor α (RXRα) in rat liver cells. We examined the effects of different fatty acids (myristic, stearic, oleic, linolenic, and arachidonic acids
Externí odkaz:
https://doaj.org/article/1d7d6d4e97854a77a8ee3d9a095691dc
Autor:
Hilde I. Nebb, Kari Anne Risan Tobin, Øystein Spydevold, Hilde Hermansen Steineger, Jan-Åke Gustafsson, Johan Auwerx, Siegfried Alberti
Publikováno v:
Molecular Endocrinology. 14:741-752
LXR alpha (liver X receptor, also called RLD-1) is a nuclear receptor, highly expressed in tissues that play a role in lipid homeostasis. In this report we show that fatty acids are positive regulators of LXR alpha gene expression and we investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9493a3a9824d454fe7b6e2e1fef98945
https://doi.org/10.1210/mend.14.5.0459
https://doi.org/10.1210/mend.14.5.0459
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1436:541-549
Liver carnitine palmitoyltransferase I (CPT I), the rate-limiting enzyme of mitochondrial beta-oxidation, rapidly loses its activity when hepatocytes are put in culture. 3-Thia fatty acids reactivate the enzyme and can increase its activity 3-4-fold
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c2abf4c614fc093ddeb354f217cfbfc
https://doi.org/10.1016/s0005-2760(98)00164-7
https://doi.org/10.1016/s0005-2760(98)00164-7
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 4, Pp 744-754 (1998)
This work describes the molecular mechanisms of fatty acid and hormonal modulations of the retinoid X recep- tor a (RXR a ) in rat liver cells. We examined the effects of dif- ferent fatty acids (myristic, stearic, oleic, linolenic, and arachi- donic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cfdb9232ca056195bcecc5b86ff66c4
http://www.sciencedirect.com/science/article/pii/S0022227520325633
http://www.sciencedirect.com/science/article/pii/S0022227520325633
Autor:
R.S. Horn, Laila N. Larsen, Jon Bremer, Hilde Nebb Sørensen, Øystein Spydevold, Steinar Skrede, Kjerstin E. Høvik, Hilde Hermansen Steineger
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1344:115-131
(1) The chemical properties of thia fatty acids are similar to normal fatty acids, but their metabolism (see below: points 2-6) and metabolic effects (see below: points 7-15) differ greatly from these and are dependent upon the position of the sulfur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e03666c93347fc20dc86b80358fa0b57
https://doi.org/10.1016/s0005-2760(96)00138-5
https://doi.org/10.1016/s0005-2760(96)00138-5
Autor:
Hilde Nebb Sørensen, Jon Bremer, Eyvind J. Paulssen, Øystein Spydevold, Erlend Hvattum, Kaare M. Gautvik
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1171:263-271
The effects of tetradecylthioacetic acid (TTA) (50 μM), dexamethasone (0.25 μM) and insulin (0.4 μM) on induction of peroxisomal acyl-CoA oxidase activity and mRNA levels were studied in short term cultures of Morris 7800C1 and MH1C1 hepatoma cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::359e9e392c1fd8760cd40b60b964fc2b
https://doi.org/10.1016/0167-4781(93)90064-k
https://doi.org/10.1016/0167-4781(93)90064-k
Autor:
Øystein Spydevold, Bente Haughom
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1128:65-72
The influence of the peroxisomal proliferators perfluorooctanoic acid (PFOA), perfluorooctane sulphonic acid (PFOSA) and clofibric acid on lipid metabolism in rats was studied. Dietary treatment of male Wistar rats with these three compounds resulted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2057771a51b5617eaa2d2e815d806bba
https://doi.org/10.1016/0005-2760(92)90258-w
https://doi.org/10.1016/0005-2760(92)90258-w
Publikováno v:
European Journal of Biochemistry. 208:705-711
This work describes the molecular mechanism of hormonal modulation of fatty-acid peroxisomal beta oxidation in liver. Morris 7800C1 hepatoma cells and isolated hepatocytes were cultured in the presence of myristic acid (1 mM) and tetradecylthioacetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99c4241a84a615fcd26e1e8f8765f28f
https://doi.org/10.1111/j.1432-1033.1992.tb17238.x
https://doi.org/10.1111/j.1432-1033.1992.tb17238.x
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1051:319-323
(1) The relation between the effects of the sulfur-substituted fatty acid analogue, tetradecylthioacetic acid (TTA), dexamethasone and insulin on enzyme induction and growth rate was studied in Morris hepatoma 7800 C1 cells in culture. (2) The activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3d4c5f1a7d821e43cbd38bea47c2f87
https://doi.org/10.1016/0167-4889(90)90141-y
https://doi.org/10.1016/0167-4889(90)90141-y
Publikováno v:
International Journal of Biochemistry. 22:1171-1177
1. Uptake and binding of dexamethasone to glucocorticoid receptor has been studied in Morris hepatoma 7800 C1 cells in relation to its effect on cell growth and peroxisomal beta-oxidation. 2. Intact cells showed saturable, specific dexamethasone bind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42bd3edc371ea3c2afe9b35d11c7baa5
https://doi.org/10.1016/0020-711x(90)90117-l
https://doi.org/10.1016/0020-711x(90)90117-l