Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Øystein Åmellem"'
Publikováno v:
Cell and Gene Therapy Insights. 5:803-807
Counteraction of pRb-dependent protection after extreme hypoxia by elevated ribonucleotide reductase
Autor:
Øystein Åmellem, Trond Stokke, Pål Graff, J. Seim, H Arakawa, Erik O. Pettersen, Kerstin Andersson, Y Nakamura
Publikováno v:
Cell Proliferation. 37:367-383
We have studied hypoxia‐induced cell cycle arrest in human cells where the retinoblastoma tumour suppressor protein (pRb) is either functional (T‐47D and T‐47DHU‐res cells) or abrogated by expression of the HPV18 E7 oncoprotein (NHIK 3025 cel
Publikováno v:
Cell Proliferation. 36:321-332
We have studied hypoxia-induced cell cycle arrest in human cells where the retinoblastoma tumour suppressor protein (pRB) is either functional (T-47D cells) or abrogated by expression of the HPV18 E7 oncoprotein (NHIK 3025 cells). All cells in S phas
Publikováno v:
International Journal of Radiation Biology. 79:413-422
To investigate the radiosensitivity of human breast cancer cells, T-47D, irradiated with low dose-rates and to study activation of the retinoblastoma gene product in the G1 and G2 phases during irradiation.Cells were irradiated with (60)Co gamma-rays
Publikováno v:
International Journal of Radiation Biology. 77:319-328
To investigate cell cycle progression and radiation survival following prolonged hypoxia and re-oxygenation.NHIK 3025 human cervical carcinoma cells were exposed to extremely hypoxic conditions (4ppm O2) for 20 h and then re-oxygenated. The subsequen
Publikováno v:
Cancer. 67:1874-1877
The DNA stemline ploidy was assessed in paraffin-embedded, formalin-fixed primary tumor tissue from 68 patients with nonseminomatous germ cell cancer (NSCGT) clinical Stage I (CS I). Forty-three patients had a single aneuploid (greater than 1C) DNA s
Autor:
Øystein Åmellem, Erik O. Pettersen
Publikováno v:
Cell Proliferation. 24:127-141
Cycling mammalian cells that are rendered extremely hypoxic (less than 4 ppm O2) tend to accumulate in a pre-DNA-synthesis stage. It is not clear whether or not this is the result of an active regulation by the cells. In the present study we have ren
Autor:
Arne Schousboe, Jorma Keski-Oja, Erik Olai Pettersen, Ursula Sonnewald, Juliana Denekamp, Peter Ebbesen, Vladimir Zachar, Bo Littbrand, Øystein Åmellem
Publikováno v:
Ebbesen, P, Pettersen, E O, Denekamp, J, Littbrand, B, Keski-Oja, J, Schousboe, A, Sonnewald, U, Amellem, O & Zachar, V 2000, ' Hypoxia, normoxia and hyperoxia-Terminology for medical in vitro cell biology ', Acta Oncologica, vol. 39, no. 2, pp. 247-248 . https://doi.org/10.1080/028418600430888
From the Danish Cancer Society, Department of Virus and Cancer, Aarhus, Denmark (P. Ebbesen, V. Zachar), Department of Biophysics, Research Section for Plasma and Space Physics, University of Oslo, Norway (E.O. Pettersen), Department of Oncology, Ume
Publikováno v:
British Journal of Cancer
We have studied the role of the oxygen-dependent pyrimidine metabolism in the regulation of cell cycle progression under moderate hypoxia in human cell lines containing functional (T-47D) or non-functional (NHIK 3025, SAOS-2) retinoblastoma gene prod
Publikováno v:
Experimental cell research. 232(2)
We have studied hypoxia-induced inactivation of cells from three established human cell lines with different p53 status. Hypoxia was found to induce apoptosis in cells expressing wild-type p53 (MCF-7 cells), but not in cells where p53 is either mutat