Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Özlem Atlı"'
Autor:
Ulviye Acar Çevik, Betül Kaya, Ismail Celik, Mithun Rudrapal, Gourav Rakshit, Arzu Karayel, Serkan Levent, Derya Osmaniye, Begüm Nurpelin Sağlık Özkan, Merve Baysal, Özlem Atlı Ekliog̈lu, Yusuf Özkay, Zafer Asım Kaplancıklı
Publikováno v:
ACS Omega, Vol 9, Iss 11, Pp 13359-13372 (2024)
Externí odkaz:
https://doaj.org/article/fac35e2ed1054edda390f0b16ea7e2f3
Autor:
Cankız Mina Ardıç, Sinem Ilgın, Merve Baysal, A. Burak Karaduman, Volkan Kılıç, Gözde Aydoğan-Kılıç, Şeyda Uçarcan, Özlem Atlı-Eklioğlu
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Although it is reported that olanzapine (OLZ), which is an atypical antipsychotic drug, causes sexual dysfunction in men, it is noteworthy that there is not any study evaluating the toxic effects of OLZ on the male reproductive system. In th
Externí odkaz:
https://doaj.org/article/e39f4272ea974f21a5a597316552945d
Autor:
Begüm Nurpelin Sağlık, Derya Osmaniye, Ulviye Acar Çevik, Serkan Levent, Betül Kaya Çavuşoğlu, Özlem Atlı Eklioğlu, Yusuf Özkay, Ali Savaş Koparal, Zafer Asım Kaplancıklı
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 1422-1432 (2020)
Many studies have been conducted on the selective inhibition of human monoamine oxidase B (hMAO-B) enzyme using benzylamine-sulphonamide derivatives. Using various chemical modifications on BB-4h, which was reported previously by our team and showed
Externí odkaz:
https://doaj.org/article/5c8f89ef95f14cababecb6d378950914
Autor:
Ulviye Acar Çevik, Begüm Nurpelin Sağlık, Derya Osmaniye, Serkan Levent, Betül Kaya Çavuşoğlu, Abdullah Burak Karaduman, Özlem Atlı Eklioğlu, Yusuf Özkay, Zafer Asım Kaplancıklı
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 1657-1673 (2020)
In this study, some benzimidazole-oxadiazole derivatives were synthesised and tested for their in vitro anticancer activities on five cancer cell lines, including HeLa, MCF7, A549, HepG2 and C6. Their structures were elucidated by IR, 1H-NMR, 13C-NMR
Externí odkaz:
https://doaj.org/article/8d3d80b3ed0b41ec929c75178d5bc4f6
Autor:
Hülya Karaca Gençer, Ulviye Acar Çevik, Betül Kaya Çavuşoğlu, Begüm Nurpelin Sağlık, Serkan Levent, Özlem Atlı, Sinem Ilgın, Yusuf Özkay, Zafer Asım Kaplancıklı
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 732-745 (2017)
Externí odkaz:
https://doaj.org/article/b7ef0a6b8edc42448ae8c1823e730eb9
Autor:
Mehlika Dilek Altıntop, Ahmet Özdemir, Gülhan Turan-Zitouni, Sinem Ilgın, Özlem Atlı, Fatih Demirci, Zafer Asım Kaplancıklı
Publikováno v:
Molecules, Vol 19, Iss 9, Pp 14809-14820 (2014)
Fourteen new thiazolyl hydrazone derivatives were synthesized and evaluated for their anticandidal activity using a broth microdilution assay. Among the synthesized compounds, 2-[2-((5-(4-chloro-2-nitrophenyl)furan-2-yl)methylene)hydrazinyl]-4-(4-flu
Externí odkaz:
https://doaj.org/article/a684bc70ae664a36b710730f551696fb
Autor:
Ahmet Çağrı Karaburun, Betül Kaya Çavuşoğlu, Ulviye Acar Çevik, Derya Osmaniye, Begüm Nurpelin Sağlık, Serkan Levent, Yusuf Özkay, Özlem Atlı, Ali Savaş Koparal, Zafer Asım Kaplancıklı
Publikováno v:
Molecules, Vol 24, Iss 1, p 191 (2019)
Discovery of novel anticandidal agents with clarified mechanisms of action, could be a rationalist approach against diverse pathogenic fungal strains due to the rise of resistance to existing drugs. In support to this hypothesis, in this paper, a ser
Externí odkaz:
https://doaj.org/article/312e4797704247aea43c0d3f2bad17de
Autor:
Ahmet Özdemir, Mehlika Dilek Altıntop, Belgin Sever, Hülya Karaca Gençer, Handan Açelya Kapkaç, Özlem Atlı, Merve Baysal
Publikováno v:
Molecules, Vol 22, Iss 12, p 2112 (2017)
In an effort to develop new potent antimicrobial and anticancer agents, new pyrrole-based chalcones were designed and synthesized via the base-catalyzed Claisen-Schmidt condensation of 2-acetyl-1-methylpyrrole with 5-(aryl)furfural derivatives. The c
Externí odkaz:
https://doaj.org/article/5cd437ef9afe49cca1873843231f0d10
Autor:
Serkan Levent, Betül Kaya Çavuşoğlu, Begüm Nurpelin Sağlık, Derya Osmaniye, Ulviye Acar Çevik, Özlem Atlı, Yusuf Özkay, Zafer Asım Kaplancıklı
Publikováno v:
Molecules, Vol 22, Iss 11, p 2004 (2017)
In the field of infection management, it is a major challenge to discover a potent and safe antifungal agent due to the emergence of resistant strains. Hence, the goal of this paper is to design and synthesize novel oxadiazole-thiadiazole hybrid comp
Externí odkaz:
https://doaj.org/article/6a8b44c1acf14c09affcafaec38621ca
Publikováno v:
Proceedings, Vol 1, Iss 6, p 647 (2017)
Lanosterol 14α-demethylase (CYP51) is an essential enzyme in the fungal life cycle and also an important target for antifungal drug development. Selective inhibition of the enzyme would cause depletion of ergosterol and accumulation of lanosterol an
Externí odkaz:
https://doaj.org/article/6b00b36812be4535b5fc8fb18fbecc9b