Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Özlem Özdemir Tozlu"'
Autor:
Cheng Zhang, Mengnan Shi, Woonghee Kim, Muhammad Arif, Martina Klevstig, Xiangyu Li, Hong Yang, Cemil Bayram, Ismail Bolat, Özlem Özdemir Tozlu, Ahmet Hacımuftuoglu, Serkan Yıldırım, Jihad Sebhaoui, Shazia Iqbal, Yongjun Wei, Xiaojing Shi, Jens Nielsen, Hasan Turkez, Mathias Uhlen, Jan Boren, Adil Mardinoglu
Publikováno v:
EBioMedicine, Vol 83, Iss , Pp 104214- (2022)
Summary: Background: Non-alcoholic fatty liver disease (NAFLD) encompasses a wide spectrum of liver pathologies. However, no medical treatment has been approved for the treatment of NAFLD. In our previous study, we found that PKLR could be a potentia
Externí odkaz:
https://doaj.org/article/36818a6a57cf492cbc5540d8d174de87
Autor:
Özlem Özdemir Tozlu, Hasan Türkez, Ufuk Okkay, Onur Ceylan, Cemil Bayram, Ahmet Hacımüftüoğlu, Adil Mardinoğlu
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
Alzheimer’s disease (AD) is a neurodegenerative disease characterized by the accumulation of amyloid-β (Aβ) plaques and neurofibrillary tangles in the brain accompanied by synaptic dysfunction and neurodegeneration. No effective treatment has bee
Externí odkaz:
https://doaj.org/article/aa774cf68e1e47b2b3ee7beb875a5a51
Publikováno v:
Erzurum Technical University.
Prostate cancer is the second leading cause of death from cancer in men. Androgen deprivation therapy (ADT) is used as the standard treatment for prostate cancer, and this treatment has undesirable side effects over time. There is a need for more eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::299beef83240abe1fc7e4d734e5a2862
https://doi.org/10.54672/ejmbs.2022.10
https://doi.org/10.54672/ejmbs.2022.10
Publikováno v:
Turkish Journal of Medical Sciences
Volume: 50, Issue: 2 448-454
Volume: 50, Issue: 2 448-454
Background/aim Aspartame (APM, L-aspartyl-L-phenylalanine methylester) is a low-calorie, nonsaccharide artificial sweetener widely used in foods and beverages. When metabolized by the body, APM is broken down into aspartic acid, phenylalanine amino a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a5323306e98560802c1f1a8e902b1cd
http://europepmc.org/articles/PMC7164759
http://europepmc.org/articles/PMC7164759
Publikováno v:
Turkish Journal of Biochemistry. 44:692-698
Objectives Dapagliflozin (DAPA), is a potent SGLT-2 inhibitor for the treatment of patients with type 2 diabetes. DAPA has a good clinical and biological tolerance profile. However little information is available on its potential effects on cultured
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dec957377250b1ad3a6c1ef918361e1
https://doi.org/10.1515/tjb-2019-0111
https://doi.org/10.1515/tjb-2019-0111
Publikováno v:
Neurochemistry international. 150
Glioblastoma (GBM) is considered one of the most common malignant brain tumors, occurring as over 15% of all primary central nervous system and brain neoplasms. The unique and standard treatment option towards GBM involves the combination of surgical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff9348dff65837fd250478a9c1afd1ee
https://pubmed.ncbi.nlm.nih.gov/34450218
https://pubmed.ncbi.nlm.nih.gov/34450218
Autor:
Erdal Sönmez, Özlem Özdemir Tozlu, Kübra Bayindirli, Süleyman Kerli, Elanur Aydin Karatas, Aysenur Yazici, Hasan Turkez
Publikováno v:
Volume: 11, Issue: 3 2307-2318
Journal of the Institute of Science and Technology
Journal of the Institute of Science and Technology
Yttrium oxide (Y2O3) nanoparticles have very wide application areas such as biological imaging, photodynamic therapy, the material sciences, in the chemical synthesis of inorganic compounds, additives in plastic, paint, steel, optics, and iron. Poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94c0677314273343bf618be24ac93c6c
https://dergipark.org.tr/tr/pub/jist/issue/64410/872394
https://dergipark.org.tr/tr/pub/jist/issue/64410/872394
Autor:
Ismail Bolat, Seyda Cankaya, Simon Lam, Cheng Zhang, Ahmet Hacimuftuoglu, Jan Borén, Rahim Nogaylar, sena oner, Özlem Özdemir Tozlu, Saeed Shoaie, Mehmet Arslan, Jens C. O. Nielsen, Ozlem Altay, Mathias Uhlén, Muhammad Arif, Ezgi İdil, Cemil Bayram, Hasan Turkez, Ebru Coskun, Xiangyu Li, Burak Yulug, Lutfu Hanoglu, Hong Yang, Adil Mardinoglu, Serkan Yildirim
Publikováno v:
SSRN Electronic Journal.
Alzheimer’s disease (AD) is associated with metabolic abnormalities linked to critical elements of neurodegeneration. Here, we analysed the brain transcriptomics data of more than 600 AD patients using genome-scale metabolic models and provided sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12395d82b2017c7da401733eacc3b36a
https://doi.org/10.2139/ssrn.3924201
https://doi.org/10.2139/ssrn.3924201
Autor:
Recep Küçükdoğru, Adil Mardinoglu, Ivana Cacciatore, Erdal Sönmez, Antonio Di Stefano, Özlem Özdemir Tozlu, Mehmet Arslan, Hasan Turkez
Publikováno v:
Metabolic brain disease. 35(6)
Parkinson’s disease (PD) is one of the most aggressive neurodegenerative diseases and characterized by the loss of dopamine-sensitive neurons in the substantia nigra region of the brain. There is no any definitive treatment to completely cure PD an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89a5dffc5249b4770f84dc5478d77372
https://pubmed.ncbi.nlm.nih.gov/32215836
https://pubmed.ncbi.nlm.nih.gov/32215836
Autor:
Akif Evren Parlak, Hasan Turkez, Kamuran Saraç, Özlem Özdemir Tozlu, Fatih Çağlar Çelikezen, Cahit Orek
Publikováno v:
Journal of Molecular Structure. 1205:127577
Coumarins have a wide usage area in medicinal applications. It is known that the design and synthesis of new coumarin derivatives are performed to prepare new drugs in many laboratories. The aim of the study was to synthesize 6-ethoxy-4-methylcoumari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edac87071cdca388044cecbc525f3f04
https://doi.org/10.1016/j.molstruc.2019.127577
https://doi.org/10.1016/j.molstruc.2019.127577