Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Özkan Danış"'
Autor:
İlkay Küçükgüzel, İlker Demirbolat, Necla Kulabaş, Merve Gürboğa, Özlem Bingöl Özakpınar, Gamze Çiftçi, Kemal Yelekçi, Jianyang Liu, Per-Johan Jakobsson, Özkan Danış, Ayşe Ogan
Publikováno v:
Organic Communications. :356-377
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa8e3c1bd2a387b1a07c84bd8cc02273
https://doi.org/10.25135/acg.oc.142.2212.2651
https://doi.org/10.25135/acg.oc.142.2212.2651
Autor:
Necla Kulabaş, İrem Set, Göknur Aktay, Şule Gürsoy, Özkan Danış, Ayşe Ogan, Safiye Sağ Erdem, Pınar Erzincan, Sinem Helvacıoğlu, Muhammed Hamitoğlu, İlkay Küçükgüzel
Today, usage of NSAIDs (nonsteroidal anti-inflammatory drugs) is very common. However, it has been proven by many studies that NSAIDs with free carboxylic acid group damage the GI (gastrointestinal) system. Our aim was to mask the acidic groups of NS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1c7c30d52eaca2b8267e036ce81ccdd
https://hdl.handle.net/11424/288894
https://hdl.handle.net/11424/288894
Autor:
Basak Yuce-Dursun, Özkan Danış, Lalehan Ozalp, Elif Sahin, Serap Demir, Safiye Sağ Erdem, Ayse Ogan
A series of 3-aryl coumarin derivatives and 3-phenylazo-4-hydroxycoumarin were evaluated for their monoamine oxidase (MAO) A and B inhibitory activity and selectivity by fluorometric enzymological assays. Among 21 coumarin derivatives, compound 21 (3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dd4353f6cbe6fa2de2897a8499079ff
https://hdl.handle.net/11424/283705
https://hdl.handle.net/11424/283705
Publikováno v:
Protein Expression and Purification. 202:106187
Recombinant expression and purification of proteins have become a staple of modern drug discovery as it enables more precise in vitro analyses of drug targets, which may help obtain biochemical and biophysical parameters of a known enzyme and even un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da051ff42aec10ee15019db63ee629d2
https://doi.org/10.1016/j.pep.2022.106187
https://doi.org/10.1016/j.pep.2022.106187
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 74:128917
Development of new selective reversible monoamine oxidase (MAO) B inhibitors is still essential for the treatment of Alzheimer's and Parkinson's disease. Phthalonitrile compounds have been shown to display MAO inhibitory activity with MAO-B selectivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53cbbab3b8557fc7770c62cd892b047f
https://doi.org/10.1016/j.bmcl.2022.128917
https://doi.org/10.1016/j.bmcl.2022.128917
Publikováno v:
Archiv der Pharmazie. 348(9)
Glutathione S-transferases (EC: 2.5.1.18, GSTs) are phase II detoxification enzymes that catalyze the conjugation of various electrophilic compounds to glutathione (GSH), thus usually producing less reactive and more water soluble compounds. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::83a98e871065e896f113db91ed672d18
https://pubmed.ncbi.nlm.nih.gov/26205366
https://pubmed.ncbi.nlm.nih.gov/26205366