Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Örn Almarsson"'
Autor:
Siddharth Patel, N. Ashwanikumar, Ema Robinson, Yan Xia, Cosmin Mihai, Joseph P. Griffith, Shangguo Hou, Adam A. Esposito, Tatiana Ketova, Kevin Welsher, John L. Joyal, Örn Almarsson, Gaurav Sahay
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Endosomal sequestration of lipid-based nanoparticles is a barrier to delivery of nucleic acids. Here the authors test an array of cholesterol variants and perform in-depth investigation of nanoparticle shape, internal structure and intracellular traf
Externí odkaz:
https://doaj.org/article/9657095ce49a4c28856fa65a8bc45d65
Autor:
Kimberly J. Hassett, Kerry E. Benenato, Eric Jacquinet, Aisha Lee, Angela Woods, Olga Yuzhakov, Sunny Himansu, Jessica Deterling, Benjamin M. Geilich, Tatiana Ketova, Cosmin Mihai, Andy Lynn, Iain McFadyen, Melissa J. Moore, Joseph J. Senn, Matthew G. Stanton, Örn Almarsson, Giuseppe Ciaramella, Luis A. Brito
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 15, Iss , Pp 1-11 (2019)
mRNA vaccines have the potential to tackle many unmet medical needs that are unable to be addressed with conventional vaccine technologies. A potent and well-tolerated delivery technology is integral to fully realizing the potential of mRNA vaccines.
Externí odkaz:
https://doaj.org/article/a67efab35a6f4ecb83f57432db8444c0
Autor:
Siddharth Patel, N. Ashwanikumar, Ema Robinson, Yan Xia, Cosmin Mihai, Joseph P. Griffith, Shangguo Hou, Adam A. Esposito, Tatiana Ketova, Kevin Welsher, John L. Joyal, Örn Almarsson, Gaurav Sahay
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/128cc779536244378fda8c2ba44fd836
Autor:
Örn Almarsson, Sherry Collier, Matthew L. Peterson, Magali B. Hickey, Eugene Y. Cheung, Mark Oliveira, Renato A. Chiarella, Edwin A. Collier
Publikováno v:
Crystal Growth & Design. 22:3575-3578
Autor:
Lei Ci, Marjie Hard, Hannah Zhang, Srujan Gandham, Serenus Hua, John Wickwire, Tod Wehrman, Richard Slauter, Andrew Auerbach, Matthew Kenney, Greg Mercer, Tracy Hendrick, Örn Almarsson, Eugene Cheung, Douglas Burdette
Publikováno v:
Drug Metabolism and Disposition. :DMD-AR
Autor:
Douglas Burdette, Lei Ci, Barclay Shilliday, Richard Slauter, Andrew Auerbach, Matthew Kenney, Örn Almarsson, Eugene Cheung, Tracy Hendrick
Publikováno v:
Drug Metabolism and Disposition. :DMD-AR
Publikováno v:
Crystal Growth & Design. 2:553-562
Human malaria, one of the most striking, reemerging infectious diseases, is caused by several types of Plasmodium parasites. As the parasite digests hemoglobin in human red blood cells, the heme by...
Publikováno v:
Tetrahedron. 56:6877-6885
The solid-state chemistry of amorphous and crystalline forms of a novel cationic 1-β-methyl carbapenem antibiotic 2 is described. The lyophilized chloride salt of 2 ( 2 ·Cl) is amorphous and exhibits moisture-dependent β-lactam hydrolysis rates. H
Autor:
Suzanne M. Mayr, Mark A. Petrich, Örn Almarsson, Yunhui Wu, J. Michael Williams, John D. Stong, Michael J. Kaufman
Publikováno v:
Journal of Pharmaceutical Sciences. 87:663-666
□ Evidence is provided for the existence of a second discrete chemical form of meropenem at clinically relevant concentrations prepared from the marketed formulation of the drug. Proton and carbon-13 NMR spectra in D 2 O, coupled with tandem mass s
Publikováno v:
Tetrahedron. 51:941-952