Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ömrüm Aydin"'
Autor:
Annika Wahlström, Ömrüm Aydin, Lisa M. Olsson, Wilhelm Sjöland, Marcus Henricsson, Annika Lundqvist, Hanns-Ulrich Marschall, Rutger Franken, Arnold van de Laar, Victor Gerdes, Abraham S. Meijnikman, Dag Hofsø, Albert K. Groen, Jøran Hjelmesæth, Max Nieuwdorp, Fredrik Bäckhed
Publikováno v:
EBioMedicine, Vol 106, Iss , Pp 105265- (2024)
Summary: Background: Bariatric surgery is an effective treatment option for obesity and provides long-term weight loss and positive effects on metabolism, but the underlying mechanisms are poorly understood. Alterations in bile acid metabolism have b
Externí odkaz:
https://doaj.org/article/64840ca30a314f63b2613355386bee20
Autor:
Torsten P. M. Scheithauer, Koen Wortelboer, Maaike Winkelmeijer, Xanthe Verdoes, Ömrüm Aydin, Yair I. Z. Acherman, Maurits L. de Brauw, Max Nieuwdorp, Elena Rampanelli, Patrick A. de Jonge, Hilde Herrema
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Individuals with type 2 diabetes (T2D) show signs of low-grade inflammation, which is related to the development of insulin resistance and beta-cell dysfunction. However, the underlying triggers remain unknown. The gut microbiota is a plausible sourc
Externí odkaz:
https://doaj.org/article/bc67ff985f5b49eca2d534bb98fd13f8
Autor:
Johanna Eveliina Pyykkö, Chris Hinnen, Ömrüm Aydin, Max Nieuwdorp, L. Maurits De Brauw, Sjoerd C. Bruin, Nienke van Olst, Victor E. A. Gerdes, Robbert Sanderman, Mariët Hagedoorn
Publikováno v:
BMC Psychology, Vol 11, Iss 1, Pp 1-13 (2023)
Abstract Background Attachment avoidance and anxiety have been linked to overweight and poor health behaviours, yet the mechanisms that underpin the relationship between attachment and health behaviours are not fully understood. Self-esteem and self-
Externí odkaz:
https://doaj.org/article/e0eaf9e4bb9146b1a486a96ea3239716
Autor:
Guido J. Bakker, Abraham S. Meijnikman, Torsten P. Scheithauer, Mark Davids, Ömrüm Aydin, Thomas C. C. Boerlage, L. Maurits deBrauw, Arnold W. van deLaar, Victor E. Gerdes, Albert K. Groen, Daniël H. vanRaalte, Hilde Herrema, Max Nieuwdorp
Publikováno v:
Obesity Science & Practice, Vol 8, Iss 1, Pp 56-65 (2022)
Abstract Aims Visceral adipose tissue inflammation is a fundamental mechanism of insulin resistance in obesity and type 2 diabetes. Translocation of intestinal bacteria has been suggested as a driving factor for the inflammation. However, although ba
Externí odkaz:
https://doaj.org/article/8634882a32a6483e959e0f2d98ad71e1
Autor:
Dimitra Lappa, Abraham S. Meijnikman, Kimberly A. Krautkramer, Lisa M. Olsson, Ömrüm Aydin, Anne-Sophie Van Rijswijk, Yair I. Z. Acherman, Maurits L. De Brauw, Valentina Tremaroli, Louise E. Olofsson, Annika Lundqvist, Siv A. Hjorth, Boyang Ji, Victor E. A. Gerdes, Albert K. Groen, Thue W. Schwartz, Max Nieuwdorp, Fredrik Bäckhed, Jens Nielsen
Publikováno v:
PLoS ONE, Vol 18, Iss 3 (2023)
Weight loss through bariatric surgery is efficient for treatment or prevention of obesity related diseases such as type 2 diabetes and cardiovascular disease. Long term weight loss response does, however, vary among patients undergoing surgery. Thus,
Externí odkaz:
https://doaj.org/article/ff98972c69364e71830211bcfa198324
Autor:
Randi Bonke Mikkelsen, Tulika Arora, Kajetan Trošt, Oksana Dmytriyeva, Sune Kjærsgaard Jensen, Abraham Stijn Meijnikman, Louise Elisabeth Olofsson, Dimitra Lappa, Ömrüm Aydin, Jens Nielsen, Victor Gerdes, Thomas Moritz, Arnold van de Laar, Maurits de Brauw, Max Nieuwdorp, Siv Annegrethe Hjorth, Thue Walter Schwartz, Fredrik Bäckhed
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105683- (2022)
Summary: Obesity and diabetes are associated with inflammation and altered plasma levels of several metabolites, which may be involved in disease progression. Some metabolites can activate G protein-coupled receptors (GPCRs) expressed on immune cells
Externí odkaz:
https://doaj.org/article/d9959421ddb94ab2875da795adbdc0af
Autor:
Torsten P.M. Scheithauer, Hilde Herrema, Hongbing Yu, Guido J. Bakker, Maaike Winkelmeijer, Galina Soukhatcheva, Derek Dai, Caixia Ma, Stefan R. Havik, Manon Balvers, Mark Davids, Abraham S. Meijnikman, Ömrüm Aydin, Bert-Jan H. van den Born, Marc G. Besselink, Olivier R. Busch, Maurits de Brauw, Arnold van de Laar, Clara Belzer, Martin Stahl, Willem M. de Vos, Bruce A. Vallance, Max Nieuwdorp, C. Bruce Verchere, Daniël H. van Raalte
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Hyperglycemia and type 2 diabetes (T2D) are caused by failure of pancreatic beta cells. The role of the gut microbiota in T2D has been studied, but causal links remain enigmatic. Obese individuals with or without T2D were included from two independen
Externí odkaz:
https://doaj.org/article/51e301893b1e4bf7bc15c80a62ac3ab1
Autor:
Torsten P.M. Scheithauer, Mark Davids, Maaike Winkelmeijer, Xanthe Verdoes, Ömrüm Aydin, Maurits de Brauw, Arnold van de Laar, Abraham S. Meijnikman, Victor E.A. Gerdes, Daniël van Raalte, Hilde Herrema, Max Nieuwdorp
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Obesity and type 2 diabetes (T2D) are growing burdens for individuals and the health-care system. Bariatric surgery is an efficient, but drastic treatment to reduce body weight, normalize glucose values, and reduce low-grade inflammation. The gut mic
Externí odkaz:
https://doaj.org/article/8f1e5e44f11a454ab8578e88f09fe324
Autor:
Pieter F de Groot, Clara Belzer, Ömrüm Aydin, Evgeni Levin, Johannes H Levels, Steven Aalvink, Fransje Boot, Frits Holleman, Daniël H van Raalte, Torsten P Scheithauer, Suat Simsek, Frank G Schaap, Steven W M Olde Damink, Bart O Roep, Joost B Hoekstra, Willem M de Vos, Max Nieuwdorp
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0188475 (2017)
Environmental factors driving the development of type 1 diabetes (T1D) are still largely unknown. Both animal and human studies have shown an association between altered fecal microbiota composition, impaired production of short-chain fatty acids (SC
Externí odkaz:
https://doaj.org/article/35ce42c8358848c681d62d25dcb52ce0
Autor:
Abraham S. Meijnikman, Casper C. van Olden, Ömrüm Aydin, Hilde Herrema, Dorota Kaminska, Dimitra Lappa, Ville Männistö, Valentina Tremaroli, Louise E. Olofsson, Maurits de Brauw, Arnold van de Laar, Joanne Verheij, Victor E.A. Gerdes, Thue W. Schwartz, Jens Nielsen, Fredrik Bäckhed, Päivi Pajukanta, Jussi Pihlajamäki, Tamar Tchkonia, James L. Kirkland, Folkert Kuipers, Max Nieuwdorp, Albert K. Groen
Publikováno v:
Diabetes, 71(9), 1929-1936. American Diabetes Association Inc.
Meijnikman, A S, van Olden, C C, Aydin, Ö, Herrema, H, Kaminska, D, Lappa, D, Männistö, V, Tremaroli, V, Olofsson, L E, de Brauw, M, van de Laar, A, Verheij, J, Gerdes, V E A, Schwartz, T W, Nielsen, J, Bäckhed, F, Pajukanta, P I, Pihlajamäki, J, Tchkonia, T, Kirkland, J L, Kuipers, F, Nieuwdorp, M & Groen, A K 2022, ' Hyperinsulinemia Is Highly Associated With Markers of Hepatocytic Senescence in Two Independent Cohorts ', Diabetes, vol. 71, no. 9, pp. 1929-1936 . https://doi.org/10.2337/db21-1076
Diabetes, 71(9), 1929-1936. AMER DIABETES ASSOC
Meijnikman, A S, van Olden, C C, Aydin, Ö, Herrema, H, Kaminska, D, Lappa, D, Männistö, V, Tremaroli, V, Olofsson, L E, de Brauw, M, van de Laar, A, Verheij, J, Gerdes, V E A, Schwartz, T W, Nielsen, J, Bäckhed, F, Pajukanta, P I, Pihlajamäki, J, Tchkonia, T, Kirkland, J L, Kuipers, F, Nieuwdorp, M & Groen, A K 2022, ' Hyperinsulinemia Is Highly Associated With Markers of Hepatocytic Senescence in Two Independent Cohorts ', Diabetes, vol. 71, no. 9, pp. 1929-1936 . https://doi.org/10.2337/db21-1076
Diabetes, 71(9), 1929-1936. AMER DIABETES ASSOC
Cellular senescence is an essentially irreversible growth arrest that occurs in response to various cellular stressors and may contribute to development of type 2 diabetes and Non-Alcoholic Fatty Liver Disease (NAFLD). Here, we investigated whether c