Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ólafur E, Sigurjónsson"'
Autor:
Freyr Jóhannsson, James T. Yurkovich, Steinn Guðmundsson, Ólafur E. Sigurjónsson, Óttar Rolfsson
Publikováno v:
Metabolites, Vol 14, Iss 2, p 91 (2024)
Temperature plays a fundamental role in biology, influencing cellular function, chemical reaction rates, molecular structures, and interactions. While the temperature dependence of many biochemical reactions is well defined in vitro, the effect of te
Externí odkaz:
https://doaj.org/article/9bfd54caf5d64a4fa3f6fc37421be371
Autor:
Helena Hamzehpour, Ástrós Óskarsdóttir, Helgi Jónsson, Fjóla Jónsdóttir, Ólafur E. Sigurjónsson, Bergthora S. Snorradottir
Publikováno v:
Pharmaceutics, Vol 16, Iss 1, p 64 (2023)
Retinoid-based drugs, while effective, are associated with systemic toxicity. Topical alternatives offer a safer option, and tazarotene, a third-generation synthetic retinoid, holds promise. This study investigates tazarotene’s transdermal delivery
Externí odkaz:
https://doaj.org/article/16076dcd2e0443f48787843d8562a75a
Autor:
Lea F. Buchweitz, James T. Yurkovich, Christoph Blessing, Veronika Kohler, Fabian Schwarzkopf, Zachary A. King, Laurence Yang, Freyr Jóhannsson, Ólafur E. Sigurjónsson, Óttar Rolfsson, Julian Heinrich, Andreas Dräger
Publikováno v:
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-10 (2020)
Abstract Background New technologies have given rise to an abundance of -omics data, particularly metabolomic data. The scale of these data introduces new challenges for the interpretation and extraction of knowledge, requiring the development of inn
Externí odkaz:
https://doaj.org/article/d6b35fc262944f6188fb91f69512f3df
Autor:
Þóra Sigmarsdóttir, Sarah McGarrity, Óttar Rolfsson, James T. Yurkovich, Ólafur E. Sigurjónsson
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Mesenchymal stem cells are a promising source for externally grown tissue replacements and patient-specific immunomodulatory treatments. This promise has not yet been fulfilled in part due to production scaling issues and the need to maintain the cor
Externí odkaz:
https://doaj.org/article/d108fcfe66af439fb9cad54dfeafff3b
Autor:
Thomas R. L. Klei, Stephane Begue, Anaïs Lotens, Ólafur E. Sigurjónsson, Michael D. Wiltshire, Chloë George, Peter J. M. van den Burg, Ryan Evans, Linda Larsson, Stephen Thomas, Tome Najdovski, Wiebke Handke, Juha Eronen, Birte Mallas, Dirk de Korte
Publikováno v:
Vox sanguinisREFERENCES.
DEHP, di(2-ethylhexyl) phthalate, is the most common member of the class of ortho-phthalates, which are used as plasticizers. The Medical Device Regulation has restricted the use of phthalates in medical devices. Also DEHP has been added to the Annex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32eb84eef472615fc2a0b3fdfde642f3
https://pubmed.ncbi.nlm.nih.gov/36510371
https://pubmed.ncbi.nlm.nih.gov/36510371
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2088
Metabolic network flux analysis uses genome-scale metabolic reconstructions to integrate transcriptomics, proteomics, and/or metabolomics data to allow for comprehensive interpretation of genotype to metabolic phenotype relationships. The compilation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1ef32447ff6861b14e5262797ffa72c4
https://pubmed.ncbi.nlm.nih.gov/31893377
https://pubmed.ncbi.nlm.nih.gov/31893377
Publikováno v:
Methods in Molecular Biology ISBN: 9781071601587
Metabolic network flux analysis uses genome-scale metabolic reconstructions to integrate transcriptomics, proteomics, and/or metabolomics data to allow for comprehensive interpretation of genotype to metabolic phenotype relationships. The compilation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8105c0e3e921159bbe8d2c43333165b
https://doi.org/10.1007/978-1-0716-0159-4_11
https://doi.org/10.1007/978-1-0716-0159-4_11
Autor:
Giuseppe, Paglia, Ólafur E, Sigurjónsson, Aarash, Bordbar, Óttar, Rolfsson, Manuela, Magnusdottir, Sirus, Palsson, Kristine, Wichuk, Sveinn, Gudmundsson, Bernhard O, Palsson
Publikováno v:
Transfusion
BACKGROUND: Red blood cells (RBCs) are routinely stored and transfused worldwide. Recently, metabolomics have shown that RBCs experience a three-phase metabolic decay process during storage, resulting in the definition of three distinct metabolic phe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b708cb984732f9ce8ba02d4c7327d22b
Autor:
Giuseppe, Paglia, Ólafur E, Sigurjónsson, Óttar, Rolfsson, Morten Bagge, Hansen, Sigurður, Brynjólfsson, Sveinn, Gudmundsson, Bernhard O, Palsson
Background: Platelet concentrates (PCs) can be prepared using three methods: platelet (PLT)-rich plasma, apheresis, and buffy coat. The aim of this study was to obtain a comprehensive data set that describes metabolism of buffy coat-derived PLTs duri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0f3b3d7f3b886b877d9c10c633ee4c24
http://hdl.handle.net/10281/244125
http://hdl.handle.net/10281/244125
Autor:
Giuseppe, Paglia, Ólafur E, Sigurjónsson, Óttar, Rolfsson, Soley, Valgeirsdottir, Morten Bagge, Hansen, Sigurður, Brynjólfsson, Sveinn, Gudmundsson, Bernhard O, Palsson
BackgroundPlatelet (PLT) concentrates are routinely stored for 5 to 7 days. During storage they exhibit what has been termed PLT storage lesion (PSL), which is evident by a loss of hemostatic function when transfused into patients. The overall goal o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::710e6d6390049dca5abcd478ce16fea4
http://hdl.handle.net/10281/244103
http://hdl.handle.net/10281/244103