Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Éva Sághy"'
Autor:
Imre Vörös, Éva Sághy, Krisztina Pohóczky, András Makkos, Zsófia Onódi, Gábor B. Brenner, Tamás Baranyai, Bence Ágg, Barnabás Váradi, Ágnes Kemény, Przemyslaw Leszek, Anikó Görbe, Zoltán V. Varga, Zoltán Giricz, Rainer Schulz, Zsuzsanna Helyes, Péter Ferdinandy
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Little is known about the role of the neuropeptide somatostatin (SST) in myocardial ischemia/reperfusion injury and cardioprotection. Here, we investigated the direct cardiocytoprotective effect of SST on ischemia/reperfusion injury in cardiomyocyte
Externí odkaz:
https://doaj.org/article/dcbc88f896f543ad8ae2da1ca762c860
Autor:
Imre Vörös, Zsófia Onódi, Viktória Éva Tóth, Tamás G. Gergely, Éva Sághy, Anikó Görbe, Ágnes Kemény, Przemyslaw Leszek, Zsuzsanna Helyes, Péter Ferdinandy, Zoltán V. Varga
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1573 (2022)
Dipeptidyl-peptidase-4 (DPP4) inhibitors are novel medicines for diabetes. The SAVOR-TIMI-53 clinical trial revealed increased heart-failure-associated hospitalization in saxagliptin-treated patients. Although this side effect could limit therapeutic
Externí odkaz:
https://doaj.org/article/b9b1068e730841bcbfb1bdb37cef836e
Autor:
Éva Sághy, Maja Payrits, Tünde Bíró-Sütő, Rita Skoda-Földes, Eszter Szánti-Pintér, János Erostyák, Géza Makkai, György Sétáló, Jr., László Kollár, Tamás Kőszegi, Rita Csepregi, János Szolcsányi, Zsuzsanna Helyes, Éva Szőke
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 10, Pp 1851-1863 (2018)
Transient Receptor Potential (TRP) cation channels, like the TRP Vanilloid 1 (TRPV1) and TRP Ankyrin 1 (TRPA1), are expressed on primary sensory neurons. These thermosensor channels play a role in pain processing. We have provided evidence previously
Externí odkaz:
https://doaj.org/article/275692ed1a07417d8ba4ed8ba39d772d
Autor:
Valéria Tékus, Ádám István Horváth, Kata Csekő, Krisztina Szabadfi, Andrea Kovács-Valasek, Bese Dányádi, László Deres, Róbert Halmosi, Éva Sághy, Zoltán V. Varga, Ernest Adeghate, Tamás Kőszegi, Péter Mátyus, Róbert Gábriel, Péter Ferdinandy, Erika Pintér, Zsuzsanna Helyes
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 134, Iss , Pp 111105- (2021)
Diabetes mellitus is a common metabolic disease leading to hyperglycemia due to insufficient pancreatic insulin production or effect. Amine oxidase copper containing 3 (AOC3) is an enzyme that belongs to the semicarbazide-sensitive amine oxidase fami
Externí odkaz:
https://doaj.org/article/58d82bcd6dbd4df3904db0c3d4c3209c
Autor:
Ádám Horváth, Maja Payrits, Anita Steib, Boglárka Kántás, Tünde Biró-Süt, János Erostyák, Géza Makkai, Éva Sághy, Zsuzsanna Helyes, Éva Szőke
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Transient Receptor Potential (TRP) Vanilloid 1 and Ankyrin 1 (TRPV1, TRPA1) cation channels are expressed in nociceptive primary sensory neurons, and integratively regulate nociceptor and inflammatory functions. Lipid rafts are liquid-ordered plasma
Externí odkaz:
https://doaj.org/article/45c6cb8a94de4eab8d76bbc60679ead5
Autor:
Dóra Szabó, Zsolt Sárszegi, Beáta Polgár, Éva Sághy, Dóra Reglődi, Tünde Tóth, Zsófia Onódi, Przemyslaw Leszek, Zoltán V. Varga, Zsuzsanna Helyes, Ágnes Kemény, Péter Ferdinandy, Andrea Tamás
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3715 (2022)
Pituitary adenylate cyclase activating polypeptide-38 (PACAP-38) is a multifunctional neuropeptide, which may play a role in cardioprotection. However, little is known about the presence of PACAP-38 in heart failure (HF) patients. The aim of our stud
Externí odkaz:
https://doaj.org/article/f42f53f9795a46be8db46dfd4cd71f43
Autor:
Maja Payrits, Ádám Horváth, Tünde Biró-Sütő, János Erostyák, Géza Makkai, Éva Sághy, Krisztina Pohóczky, Angéla Kecskés, Miklós Kecskés, János Szolcsányi, Zsuzsanna Helyes, Éva Szőke
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 14, p 5019 (2020)
Transient Receptor Potential Vanilloid 1 and Ankyrin 1 (TRPV1, TRPA1) cation channels are expressed in nociceptive primary sensory neurons and regulate nociceptor and inflammatory functions. Resolvins are endogenous lipid mediators. Resolvin D1 (RvD1
Externí odkaz:
https://doaj.org/article/d4c46128d8494e87bd0286926b2a24f8
Autor:
Éva Sághy, Imre Vörös, Bence Ágg, Bernadett Kiss, Gábor Koncsos, Zoltán V. Varga, Anikó Görbe, Zoltán Giricz, Rainer Schulz, Péter Ferdinandy
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2128 (2020)
Little is known about the mechanism of prediabetes-induced cardiac dysfunction. Therefore, we aimed to explore key molecular changes with transcriptomic and bioinformatics approaches in a prediabetes model showing heart failure with preserved ejectio
Externí odkaz:
https://doaj.org/article/bbce671e5dd444248d8d0080cf668616
Autor:
Gábor B. Brenner, András Makkos, Csilla Terézia Nagy, Zsófia Onódi, Nabil V. Sayour, Tamás G. Gergely, Bernadett Kiss, Anikó Görbe, Éva Sághy, Zoltán S. Zádori, Bernadette Lázár, Tamás Baranyai, Richárd S. Varga, Zoltán Husti, András Varró, László Tóthfalusi, Rainer Schulz, István Baczkó, Zoltán Giricz, Péter Ferdinandy
Publikováno v:
Cells, Vol 9, Iss 3, p 551 (2020)
Cardiac adverse effects are among the leading causes of the discontinuation of clinical trials and the withdrawal of drugs from the market. The novel concept of ‘hidden cardiotoxicity’ is defined as cardiotoxicity of a drug that manifests in the
Externí odkaz:
https://doaj.org/article/e64b79f188254c80abf4399ea382fcad
Autor:
Éva Sághy, László Köles, Tamas L. Horvath, Eszter Berekméri, Tímea Téglás, Máté Aller, Orsolya Deák, Tibor Zelles, Adam Fekete
Publikováno v:
Hearing Research. 371:75-86
Ca2+ is an important intracellular messenger and regulator in both physiological and pathophysiological mechanisms in the hearing organ. Investigation of cellular Ca2+ homeostasis in the mature cochlea is hampered by the special anatomy and high vuln