Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Éva Garabuczi"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Extensive mechanical stress frequently causes micro-traumas in skeletal muscle, followed by a regeneration period. The effective removal of dead myofibers is a prerequisite for proper regeneration, and several cell types, including professio
Externí odkaz:
https://doaj.org/article/e3f29f6abb734c55b14bcd401d186091
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 4, Pp 1961-1973 (2022)
Abstract Sarcopenia is a progressive loss of muscle mass and strength with a risk of adverse outcomes such as disability, poor quality of life, and death. Increasing evidence indicates that diminished ability of the muscle to activate satellite cell
Externí odkaz:
https://doaj.org/article/6469b7dceef74371983ca245904cd4c1
Autor:
Éva Garabuczi, Nastaran Tarban, Éva Fige, Andreas Patsalos, László Halász, Tímea Szendi-Szatmári, Zsolt Sarang, Róbert Király, Zsuzsa Szondy
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Macrophage polarization is a process whereby macrophages develop a specific phenotype and functional response to different pathophysiological stimuli and tissue environments. In general, two main macrophage phenotypes have been identified: inflammato
Externí odkaz:
https://doaj.org/article/b02fefc7c6a54cac819877a465b39c83
Publikováno v:
Cells, Vol 11, Iss 21, p 3502 (2022)
Every day, billions of our cells die and get cleared without inducing inflammation. When, clearance is improper, uncleared cells undergo secondary necrosis and trigger inflammation. In addition, proper efferocytosis would be required for inducing res
Externí odkaz:
https://doaj.org/article/8dc9d50aa307493f8cffb8a7667015fe
Autor:
Nastaran Tarban, Hajnalka Halász, Péter Gogolák, Éva Garabuczi, Alexander R. Moise, Krzysztof Palczewski, Zsolt Sarang, Zsuzsa Szondy
Publikováno v:
Cells, Vol 11, Iss 8, p 1333 (2022)
Skeletal muscle repair is initiated by local inflammation and involves the engulfment of dead cells (efferocytosis) by infiltrating macrophages at the injury site. Macrophages orchestrate the whole repair program, and efferocytosis is a key event not
Externí odkaz:
https://doaj.org/article/98625e4602194198bf82f23f14b23a7f
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
In the human body, billions of cells die by apoptosis every day. The subsequent clearance of apoptotic cells by phagocytosis is normally efficient enough to prevent secondary necrosis and the consequent release of cell contents that would induce infl
Externí odkaz:
https://doaj.org/article/b712f215922e475182543f93bf3b2b3e
Publikováno v:
Cells; Volume 11; Issue 21; Pages: 3502
Every day, billions of our cells die and get cleared without inducing inflammation. When, clearance is improper, uncleared cells undergo secondary necrosis and trigger inflammation. In addition, proper efferocytosis would be required for inducing res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::75308065c4101a8977f2e47e4c137583
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1853(3):660-670
Nur77 is a transcription factor, which plays a determinant role in mediating T cell receptor-induced cell death of thymocytes. In addition to regulation of transcription, Nur77 contributes to apoptosis induction by targeting mitochondria, where it ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b56fcb5e35c52670c07b836ca8e057f7
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1853:573-582
Efficient phagocytic clearance of apoptotic cells (efferocytosis) is essential to prevent the development of chronic inflammation and autoimmunity. Glucocorticoids are widely used in the therapy of chronic inflammatory diseases, and increasing eviden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f52570c947496baac170c76672824fb
https://doi.org/10.1016/j.bbamcr.2014.12.014
https://doi.org/10.1016/j.bbamcr.2014.12.014
Publikováno v:
The Journal of Immunology. 192:5730-5738
Previous work in our laboratory has shown that transglutaminase 2 (TG2) acting as a coreceptor for integrin β3 is required for proper phagocytosis of apoptotic cells. In the absence of TG2, systemic lupus erythematosus–like autoimmunity develops i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9a1608ef3f0e88e9cd27423775fdde9
https://doi.org/10.4049/jimmunol.1400284
https://doi.org/10.4049/jimmunol.1400284