Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Étienne Audet‐Walsh"'
Publikováno v:
Data in Brief, Vol 57, Iss , Pp 111053- (2024)
Prostate cancer is a hormone-dependent disease that relies on the androgen signaling, as well as on the estrogen signaling, for growth and survival. To identify the genes regulated by these sex-steroid hormones in the human prostate cancer cell line
Externí odkaz:
https://doaj.org/article/1c9b0d17e88247a6a797311b82c1b3d3
Publikováno v:
Data in Brief, Vol 57, Iss , Pp 110870- (2024)
Sex hormones are necessary for the development and functions of the normal prostate as well as for the initiation and progression of prostate tumors. Indeed, androgens and estrogens can activate their respective nuclear receptors to modulate the expr
Externí odkaz:
https://doaj.org/article/07e531d60ca646a69deda108b8ce90a1
Autor:
Kevin Gonthier, Cindy Weidmann, Line Berthiaume, Cynthia Jobin, Aurélie Lacouture, Camille Lafront, Mario Harvey, Bertrand Neveu, Jérémy Loehr, Alain Bergeron, Yves Fradet, Louis Lacombe, Julie Riopel, Éva Latulippe, Chantal Atallah, Michael Shum, Jean‐Philippe Lambert, Frédéric Pouliot, Martin Pelletier, Étienne Audet‐Walsh
Publikováno v:
Molecular Oncology, Vol 17, Iss 10, Pp 2109-2125 (2023)
The androgen receptor (AR) is an established orchestrator of cell metabolism in prostate cancer (PCa), notably by inducing an oxidative mitochondrial program. Intriguingly, AR regulates cytoplasmic isocitrate dehydrogenase 1 (IDH1), but not its mitoc
Externí odkaz:
https://doaj.org/article/b60b3bf0f71f4ae9996565ed221a4aac
Autor:
Aurélie Lacouture, Yann Breton, Cindy Weidmann, Sarah-Maude Goulet, Lucas Germain, Martin Pelletier, Étienne Audet-Walsh
Publikováno v:
Environment International, Vol 179, Iss , Pp 108132- (2023)
Due to its sensitivity to hormonal signaling, the mammary gland is often referred to as a sentinel organ for the study of endocrine-disrupting chemicals (EDCs), environmental pollutants that can interfere with the estrogen signaling pathway and induc
Externí odkaz:
https://doaj.org/article/c6e49e9da0ff4b198fa3d6f11128e9e9
Autor:
Gardy Lavertu, Ella Diendere, France Légaré, Hervé Tchala Vignon Zomahoun, Alfred Kodjo Toi, Mathilde Leblond, Nathalie Rheault, Étienne Audet-Walsh, Marie-Claude Beaulieu, Ali Ben Charif, Virginie Blanchette, Jean-Pierre Després, André Gaudreau, Caroline Rhéaume, Marie-Claude Tremblay, Jean-Sébastien Paquette
Publikováno v:
Translational Medicine Communications, Vol 7, Iss 1, Pp 1-6 (2022)
Abstract Translational research aims at reducing gaps between fundamental scientific discoveries and real-world applications. However, the trajectory of most scientific discoveries along the translation research continuum remains highly complex. Logi
Externí odkaz:
https://doaj.org/article/b5edf0165a6f4ca581a419ff2a49dd9c
Autor:
Jean-Sébastien Paquette, Hervé Tchala Vignon Zomahoun, Ella Diendere, Gardy Lavertu, Nathalie Rheault, Alfred Kodjo Toi, Mathilde Leblond, Étienne Audet-Walsh, Marie-Claude Beaulieu, Ali Ben Charif, Virginie Blanchette, Jean-Pierre Després, André Gaudreau, Caroline Rhéaume, Marie-Claude Tremblay, France Légaré
Publikováno v:
Translational Medicine Communications, Vol 7, Iss 1, Pp 1-19 (2022)
Abstract Background Collaboration between biomedical research and community-based primary health care actors is essential to translate evidence into clinical practice. However, little is known about the characteristics and impacts of implementing col
Externí odkaz:
https://doaj.org/article/b1d4f744e2d74b68bcb4365d0967e107
Autor:
Mathieu Paquette, Ming Yan, Josué M. J. Ramírez-Reyes, Leeanna El-Houjeiri, Marco Biondini, Catherine R. Dufour, Hyeonju Jeong, Alain Pacis, Vincent Giguère, Jennifer L. Estall, Peter M. Siegel, Étienne Audet-Walsh, Arnim Pause
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Non-alcoholic fatty liver disease (NAFLD) is the most frequent liver disease worldwide and can progress to non-alcoholic steatohepatitis (NASH), which is characterized by triglyceride accumulation, inflammation, and fibrosis. No pharmacologi
Externí odkaz:
https://doaj.org/article/1475e426b13d4372960b3695a52f08dd
Autor:
Lilianne Frégeau-Proulx, Aurélie Lacouture, Line Berthiaume, Cindy Weidmann, Mario Harvey, Kevin Gonthier, Jean-François Pelletier, Bertrand Neveu, Cynthia Jobin, Dominic Bastien, Alain Bergeron, Yves Fradet, Louis Lacombe, Isabelle Laverdière, Chantal Atallah, Frédéric Pouliot, Étienne Audet-Walsh
Publikováno v:
Molecular Metabolism, Vol 62, Iss , Pp 101516- (2022)
Objective: The prostate is metabolically unique: it produces high levels of citrate for secretion via a truncated tricarboxylic acid (TCA) cycle to maintain male fertility. In prostate cancer (PCa), this phenotype is reprogrammed, making it an intere
Externí odkaz:
https://doaj.org/article/cba98d5ecfcf4c339b2304f82a4c76f3
Autor:
Jérémy Loehr, Pata-Eting Kougnassoukou Tchara, Kevin Gonthier, Chahinez Noufi, Naomie Linteau, Étienne Audet-Walsh, Jean-Philippe Lambert
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Cellular homeostasis requires the orderly expression of thousands of transcripts. Gene expression is regulated by numerous proteins that recognize post-translational modifications—in particular, the acetylation of lysine residues (Kac) on histones.
Externí odkaz:
https://doaj.org/article/8e2fa572180346cbaa9e0df926c64900
Autor:
Lilianne Frégeau-Proulx, Aurélie Lacouture, Cindy Weidmann, Cynthia Jobin, Étienne Audet-Walsh
Publikováno v:
MethodsX, Vol 9, Iss , Pp 101843- (2022)
The prostate is a gland that contributes to men's fertility. It is highly responsive to androgens and is often the site of carcinogenesis, as prostate cancer is the most frequent cancer in men in over a hundred countries. To study the normal prostate
Externí odkaz:
https://doaj.org/article/cceb69b2c403415781f2e2c124e2154b