Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Éric Chevet"'
Autor:
Sophie Martin, Gwénaële Jégou, Aurore Nicolas, Matthieu Le Gallo, Éric Chevet, Florence Godey, Tony Avril
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101229- (2022)
Summary: This protocol describes a flow cytometry approach to evaluate antibody responses against SARS-CoV-2 transmembrane proteins in COVID-19-positive patient sera samples without the need of specific laboratory facilities for viral infection. We d
Externí odkaz:
https://doaj.org/article/faf35d5423bf4e3b8ed989ac576f1f86
Autor:
Vesna Risso, Mélissa Thomas, Blandine Guével, Regis Lavigne, Emmanuelle Com, Sophie Martin, Manon Nivet, Charles Pineau, Luc Negroni, Élodie Lafont, Éric Chevet, Leif A. Eriksson, Matthieu Le Gallo
Publikováno v:
FEBS Journal
FEBS Journal, 2023, ⟨10.1111/febs.16737⟩
FEBS Journal, 2023, ⟨10.1111/febs.16737⟩
International audience; CD95 is a member of the TNF receptor superfamily that is ubiquitously expressed in healthy and pathological tissues. Stimulation of CD95 by its physiological ligand CD95L induces its oligomerization leading in turn to the tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2e89063653da47427c8766f8c744ca0
https://hal.science/hal-03968369
https://hal.science/hal-03968369
Autor:
null Vesna Risso, null Mélissa Thomas, null Blandine Guével, null Regis Lavigne, null Emmanuelle Com, null Sophie Martin, null Manon Nivet, null Charles Pineau, null Luc Negroni, null Élodie Lafont, null Éric Chevet, null Leif A Eriksson, null Matthieu Le Gallo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d601950695c1ff8bdf3ccbd2c77b2876
https://doi.org/10.1111/febs.16737/v2/response1
https://doi.org/10.1111/febs.16737/v2/response1
Autor:
Raphael Pineau, Pierre Jean Le Reste, Tony Avril, Ulrich Jarry, Eric Chevet, Diana Pelizzari-Raymundo
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103304- (2024)
Summary: In cancer research, murine models play a crucial role as highly valuable preclinical tools. Here, we present a protocol to generate a murine model of glioblastoma through the direct intracranial injection of tumor cells. We describe steps fo
Externí odkaz:
https://doaj.org/article/d6c8208a6d204dbaa5b17d57b18891d6
Autor:
S. Jalil Mahdizadeh, Johan Grandén, Diana Pelizzari-Raymundo, Xavier Guillory, Antonio Carlesso, Eric Chevet, Leif A. Eriksson
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract The flavonoid Quercetin (Qe) was identified as an activator of Inositol-requiring enzyme 1 (IRE1) in S. cerevisiae (scIre1p), but its impact on human IRE1 (hIRE1) remains controversial due to the absence of a conserved Qe binding site. We ha
Externí odkaz:
https://doaj.org/article/987ce2cf50b941f4876954d45013c533
Autor:
Diana Pelizzari-Raymundo, Dimitrios Doultsinos, Raphael Pineau, Chloé Sauzay, Thodoris Koutsandreas, Timothy Langlais, Antonio Carlesso, Elena Gkotsi, Luc Negroni, Tony Avril, Aristotelis Chatziioannou, Eric Chevet, Leif A. Eriksson, Xavier Guillory
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106687- (2023)
Summary: Inositol-requiring enzyme 1 (IRE1) is a major mediator of the unfolded protein response (UPR), which is activated upon endoplasmic reticulum (ER) stress. Tumor cells experience ER stress due to adverse microenvironmental cues, a stress overc
Externí odkaz:
https://doaj.org/article/ec4db961d77f43c39ac1a07754c5bca7
Autor:
Saïd, Taouji, Éric, Chevet
Publikováno v:
Medecine sciences : M/S. 31(6-7)
An imbalance of protein homeostasis caused by external or internal stress in the endoplasmic reticulum triggers the initiation of signalling pathways downstream of the IRE1, ATF6 and PERK sensors to a translational or transcriptional adaptive respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::911f66c0a0d0dfb01eaeea8ce3b671b4
https://pubmed.ncbi.nlm.nih.gov/26152172
https://pubmed.ncbi.nlm.nih.gov/26152172
Autor:
Aitor Almanza, Katarzyna Mnich, Arnaud Blomme, Claire M. Robinson, Giovanny Rodriguez-Blanco, Sylwia Kierszniowska, Eoghan P. McGrath, Matthieu Le Gallo, Eleftherios Pilalis, Johannes V. Swinnen, Aristotelis Chatziioannou, Eric Chevet, Adrienne M. Gorman, Afshin Samali
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
IRE1α cleaves several mRNAs upon accumulation of misfolded proteins. Here the authors show that active IRE1α cleaves DGAT2 mRNA encoding the rate-limiting enzyme in the synthesis of triacylglycerols, suggesting a role of IRE1α in reprogramming lip
Externí odkaz:
https://doaj.org/article/5880a9d0a80d435dbe79e1dfb4bc9b6f
Sensor dimer disruption as a new mode of action to block the IRE1-mediated unfolded protein response
Autor:
Kosala N. Amarasinghe, Diana Pelizzari-Raymundo, Antonio Carlesso, Eric Chevet, Leif A. Eriksson, Sayyed Jalil Mahdizadeh
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 1584-1592 (2022)
The unfolded protein response (UPR) is activated to cope with an accumulation of improperly folded proteins in the Endoplasmic reticulum (ER). The Inositol requiring enzyme 1α (IRE1α) is the most evolutionary conserved transducer of the UPR. Activa
Externí odkaz:
https://doaj.org/article/9c0a764ffe7b4efaad7c3bc6b85214d1
Autor:
Stéphanie Lhomond, Tony Avril, Nicolas Dejeans, Konstantinos Voutetakis, Dimitrios Doultsinos, Mari McMahon, Raphaël Pineau, Joanna Obacz, Olga Papadodima, Florence Jouan, Heloise Bourien, Marianthi Logotheti, Gwénaële Jégou, Néstor Pallares‐Lupon, Kathleen Schmit, Pierre‐Jean Le Reste, Amandine Etcheverry, Jean Mosser, Kim Barroso, Elodie Vauléon, Marion Maurel, Afshin Samali, John B Patterson, Olivier Pluquet, Claudio Hetz, Véronique Quillien, Aristotelis Chatziioannou, Eric Chevet
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 2, Pp n/a-n/a (2023)
Externí odkaz:
https://doaj.org/article/61cb6bd968494a5cbfe714a2a5fc6f79