Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Éric, Godin"'
Autor:
Clémentine Minozzi, Noémie Beaucage, Mathieu Morency, Javier Guerrero‐Morales, Shawn K. Collins, Antoine Caron, Sacha Nguyen Thanh, Xavier Abel-Snape, Jeffrey Santandrea, Éric Godin, Bastien Rey
Publikováno v:
Chemistry – A European Journal. 26:14575-14579
The synthesis of rare macrocyclic alkynediyl sulfides by a Cu-catalyzed Csp -S cross-coupling is presented. The catalytic protocol (Cu(MeCN)4 PF6 /dtbbpy) promotes macrocyclization of peptides, dipeptides and tripeptides at ambient temperature (14 ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::639237e43dbc3e6e7d75cfb34af3e0e7
https://doi.org/10.1002/chem.202003655
https://doi.org/10.1002/chem.202003655
Publikováno v:
Organic Letters. 22:5905-5909
Copper-catalyzed cross-coupling of thiols and bromoalkynes affords a mild, rapid, and selective Csp-S coupling with broad scope, enabling the use of aryl-, alkyl-, and silyl-substituted alkynyl coupling partners (38 total examples, 50-99% yields). Im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::111f44442933f7bfe420edd16f701283
https://doi.org/10.1021/acs.orglett.0c02004
https://doi.org/10.1021/acs.orglett.0c02004
Publikováno v:
Organic letters. 22(15)
Copper-catalyzed cross-coupling of thiols and bromoalkynes affords a mild, rapid, and selective C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b4bc2a8cf1583b0f99170b5338a250e4
https://pubmed.ncbi.nlm.nih.gov/32667204
https://pubmed.ncbi.nlm.nih.gov/32667204
Publikováno v:
Organicbiomolecular chemistry. 18(26)
The relative stability and predictable reactivity of alkynyl sulfides make them ideal synthons for the development of new transformations. Classic methods for forming alkynyl sulfides relied on dehydrohalogenation approaches. However more recent meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e79cc0d74853f5f61b35e1e94ee753
https://pubmed.ncbi.nlm.nih.gov/32538415
https://pubmed.ncbi.nlm.nih.gov/32538415
Autor:
Clémentine Minozzi, Christina Gagnon, Corentin Pochet, Johann Sosoe, Shawn K. Collins, Éric Godin
Publikováno v:
Science (New York, N.Y.). 367(6480)
Enzymes lock in planar chirality Molecules with very large rings—macrocycles—are often conformationally constrained, and some exhibit planar chirality when substituents of the ring cannot rotate freely. Restricted rotation is generally valued in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d84e1a9a4cf30c8ea62839822f213787
https://pubmed.ncbi.nlm.nih.gov/32079773
https://pubmed.ncbi.nlm.nih.gov/32079773
Catalytic Macrocyclization Strategies Using Continuous Flow: Formal Total Synthesis of Ivorenolide A
Autor:
Shawn K. Collins, Shawn Parisien-Collette, Éric Godin, Mylène de Léséleuc, Alexandre Lévesque
Publikováno v:
The Journal of Organic Chemistry. 81:6750-6756
A formal total synthesis of ivorenolide A has been accomplished employing a Z-selective olefin cross metathesis and a macrocyclic Glaser-Hay coupling as key steps. The macrocyclization protocol employed a phase separation/continuous flow manifold who
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50390157516ffefeb4217ccda6507689
https://doi.org/10.1021/acs.joc.6b01500
https://doi.org/10.1021/acs.joc.6b01500
Autor:
Shawn K. Collins, Éric Godin
Publikováno v:
Encyclopedia of Reagents for Organic Synthesis
[107-66-4] C8H19O4P (MW 210.21) 1S/C8H19O4P/c1-3-5-7-11-13(9,10)12-8-6-4-2/h3-8H2,1-2H3,(H,9,10) InChIKey = JYFHYPJRHGVZDY-UHFFFAOYSA-N (ligand, Bronsted acid, glycosylating agent) Alternate Names: phosphoric acid dibutyl ester; dibutyl hydrogen phos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e72811ca96ba37bfdc508d3f113571f
https://doi.org/10.1002/047084289x.rn02038
https://doi.org/10.1002/047084289x.rn02038
Publikováno v:
The Journal of organic chemistry. 82(14)
A phase separation/continuous flow strategy employing an oxidative Glaser–Hay coupling of alkynes has been applied toward the synthesis of the macrocyclic core of complex pharmaceutical vaniprevir. The phase separation/continuous flow strategy affo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b5d633b705691fe4018c9ac7d621d6f
https://pubmed.ncbi.nlm.nih.gov/28677966
https://pubmed.ncbi.nlm.nih.gov/28677966
Autor:
René Allard, Micheline Lapalme, W. Edward C. Bradley, John Verner Raelson, Charles Privé, René J. A. Paulussen, Vadym Pinchuk, Abdelmajid Belouchi, Éric Godin, Helene Fournier, Daniel Dubois
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9401 (2010)
PLoS ONE
PLoS ONE
BACKGROUND: We have examined the genomic distribution of large rare autosomal deletions in a sample of 440 parent-parent-child trios from the Quebec founder population (QFP) which was recruited for a study of Attention Deficit Hyperactivity Disorder.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a9430d08f3134165280125357df963
https://doi.org/10.1371/journal.pone.0009401
https://doi.org/10.1371/journal.pone.0009401