Variable selection for data aggregated from different sources with group of variable structure

Autor: Broc, Camilo

Publikováno v: Functional Analysis [math.FA]. Université de Pau et des Pays de l'Adour; Universidad del País Vasco. Facultad de ciencias, 2019. English. ⟨NNT : 2019PAUU3048⟩

During the last decades, the amount of available genetic data on populations has growndrastically. From one side, a refinement of chemical technologies have made possible theextraction of the human genome of individuals at an accessible cost. From th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______212::23ba356c5e61c52602720b2f5faf5d99
https://tel.archives-ouvertes.fr/tel-02935022

L'étude des déterminants « -omiques » du VEGF dans la médecine personnalisée des maladies chroniques

Autor: Stathopoulou, Maria

Publikováno v: Populations and Evolution [q-bio.PE]. Université de Lorraine, 2019

The first part of this thesis presents my curriculum. A synthesis of my research activities is developed in the second part along with teaching and administrative activities. In the third part, I am developing my past and current research projects an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::99cb572d120091c2c0f7c61d20e9b0d3
https://hal.univ-lorraine.fr/tel-02360018

Gene-gene and gene-environment interactions in genetic studies of multifactorial diseases : application to asthma and atopy

Autor: Sugier, Pierre-Emmanuel

Publikováno v: Médecine humaine et pathologie. Sorbonne Université, 2018. Français. ⟨NNT : 2018SORUS519⟩

Asthma results from multiple genetic and environmental factors and from interactions between these factors. The global aim of this thesis was to propose gene-gene and gene-environment interaction strategies of analysis to identify new genes associate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d88a2b9deab487b8b646c4f0b41fc284
https://theses.hal.science/tel-03125276

Search for genetic factors controlling the response to infection by Mycobacterium tuberculosis and the development of clinical tuberculosis

Autor: Jabot-Hanin, Fabienne

Publikováno v: Génétique humaine. Université Sorbonne Paris Cité, 2017. Français. ⟨NNT : 2017USPCB253⟩

Tuberculosis remains a major public health concern, with approximately 10.4 million new cases and 1.8 million deaths due to the disease in 2015 according to WHO. While an estimated one third of the world population is estimated to be infected with My

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6dcfc700bac127e0d8c75569a1d9a624
https://tel.archives-ouvertes.fr/tel-02117942/file/va_Jabot-Hanin_Fabienne.pdf

Établissement d'une cohorte de patientes ayant consulté à l'Institut de Cancérologie de Lorraine et porteuses de la mutation BRCA1-3600del11: étude descriptive des caractéristiques cliniques et anatomo-pathologiques des cancers du sein et de l'ovaire dans cette cohorte : mise en évidence d'un phénomène d'anticipation génétique dans 38 paires mères-filles atteintes de cancer du sein ou de l'ovaire

Autor: El Tannouri, Rachelle

Publikováno v: Génétique. Université de lorraine, 2017. Français. ⟨NNT : 2017LORR0072⟩

Introduction: Over 1000 alterations in the BRCA1 gene have been documented. Most of these are frameshifts and ~10% are missense mutations that generate stop codons leading to a truncated and therefore inactive BRCA1 protein. In the French population,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______212::406f8c3b0c06ed1c4c8088dee8e95617
https://hal.univ-lorraine.fr/tel-01759166