Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Éloïc Colombo"'
Autor:
Éloïc Colombo, Dominic Duchêne, Eric Marsault, Pierre-Luc Boudreault, Antoine Désilets, Richard Leduc, Rafael Najmanovich
Publikováno v:
Journal of Medicinal Chemistry. 57:10198-10204
We studied the factors affecting the selectivity of peptidomimetic inhibitors of the highly homologous proteases matriptase and matriptase-2 across subpockets using docking simulations. We observed that the farther away a subpocket is located from th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ac2c583e948a0a3d1f99cd0c5ca9bcb
https://doi.org/10.1021/jm5015633
https://doi.org/10.1021/jm5015633
Autor:
Eric Marsault, Pierre-Luc Boudreault, Richard Leduc, Éloïc Colombo, François Béliveau, Sébastien P. Dion, Catherine St-Georges, Rafael Najmanovich, Mariana Gabriela Ghinet, Antoine Désilets
Publikováno v:
European journal of medicinal chemistry. 129
Matriptase-2, a type II transmembrane serine protease (TTSP), is expressed in the liver and regulates iron homeostasis via the cleavage of hemojuvelin. Matriptase-2 emerges as an attractive target for the treatment of conditions associated with iron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::829e4195da664856075c49bc17aa78c1
https://pubmed.ncbi.nlm.nih.gov/28219045
https://pubmed.ncbi.nlm.nih.gov/28219045
Autor:
Lauren M. Tanabe, Michael J. Duhaime, Éloïc Colombo, Karin List, Michael D. Johnson, Chen-Yong Lin, Thomas E. Hyland, Julie L. Boerner, Julie E. Lang, Richard Leduc, Gina L. Zoratti, Eric Marsault
Publikováno v:
Oncotarget, vol 7, iss 36
Oncotarget
Oncotarget
The poor prognosis for patients with inflammatory breast cancer (IBC) compared to patients with other types of breast cancers emphasizes the need to better understand the molecular underpinnings of this disease with the goal of developing effective t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fedacb3658d404f81ba6582d38525e8f
https://escholarship.org/uc/item/8b9513qt
https://escholarship.org/uc/item/8b9513qt
Autor:
Eric Marsault, Félix Chagnon, Antoine Désilets, Rafael Najmanovich, Dominic Duchêne, Éloïc Colombo, Richard Leduc
Publikováno v:
ACS Medicinal Chemistry Letters. 3:530-534
Matriptase is a member of the type II transmembrane serine protease family. Several studies have reported deregulated matriptase expression in several types of epithelial cancers, suggesting that matriptase constitutes a potential target for cancer t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9011b618e73411e41b667f55a1c57162
https://doi.org/10.1021/ml3000534
https://doi.org/10.1021/ml3000534
Autor:
Fausto A. Varela, Andrew S. Murray, Lauren M. Tanabe, Alfredo A. Molinolo, Eric Marsault, Julie L. Boerner, Karin List, Richard Leduc, Éloïc Colombo, Christopher Bergum, Gina L. Zoratti, Julie E. Lang
Publikováno v:
Nature communications, vol 6, iss 1
Nature communications
Nature communications
Matriptase is an epithelia-specific membrane-anchored serine protease that has received considerable attention in recent years because of its consistent dysregulation in human epithelial tumours, including breast cancer. Mice with reduced levels of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe04ebac749c99613273971d6ecdeb40
https://escholarship.org/uc/item/9g60f5zr
https://escholarship.org/uc/item/9g60f5zr
Autor:
Éloïc Colombo, Eric Marsault, Émilie Gravel, Alexandre Cloutier, Catherine Verreault, Antoine Désilets, A. Beaulieu, Martin V. Richter, Richard Leduc, Isabelle Marois
Publikováno v:
Journal of Virology
Influenza viruses do not encode any proteases and must rely on host proteases for the proteolytic activation of their surface hemagglutinin proteins in order to fuse with the infected host cells. Recent progress in the understanding of human protease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c71cabee61e17bf6791af81d697ba4be
https://pubmed.ncbi.nlm.nih.gov/23365447
https://pubmed.ncbi.nlm.nih.gov/23365447