Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Élisabeth Houbron"'
Autor:
Élisabeth Houbron, Sophie Mockly, Sophia Rafasse, Nathalie Gros, Delphine Muriaux, Hervé Seitz
Publikováno v:
RNA Biology, Vol 20, Iss 1, Pp 272-280 (2023)
RNA interference (RNAi) offers an efficient way to repress genes of interest, and it is widely used in research settings. Clinical applications emerged more recently, with 5 approved siRNAs (the RNA guides of the RNAi effector complex) against human
Externí odkaz:
https://doaj.org/article/92e2bdd2d7e847c691e930adad7d4420
* AbstractAssessment of the functionality of individual microRNA/target sites is a crucial issue. Genome editing techniques should theoretically permit a fine functional exploration of such interactions, allowing the mutation of microRNAs or individu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30c0a1207a765d02420f0255763f465d
https://doi.org/10.1101/2022.12.16.520740
https://doi.org/10.1101/2022.12.16.520740
Autor:
Élisabeth Houbron, Sophie Mockly, Sophia Rafasse, Nathalie Gros, Delphine Muriaux, Hervé Seitz
RNA interference (RNAi) offers an efficient way to repress genes of interest, and it is widely used in research settings. Clinical applications emerged more recently, with 5 approved siRNAs (the RNA guides of the RNAi effector complex) against human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f479d75d0c7eebfc3d5c0ba264e12d4f
https://doi.org/10.1101/2022.12.08.519651
https://doi.org/10.1101/2022.12.08.519651
Publikováno v:
Nucleic acids research. 50(8)
While several microRNAs (miRNAs) have been proposed to act as tumor suppressors, a consensual definition of tumor suppressing miRNAs is still missing. Similarly to coding genes, we propose that tumor suppressor miRNAs must show evidence of genetic or