Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Çagla Tükel"'
Autor:
Brian Le, Roberto Caricchio, Stefania Gallucci, Lauren K Nicastro, Çagla Tükel, Leah Whiteman, Kaitlyn Grando
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss Suppl 2 (2024)
Externí odkaz:
https://doaj.org/article/9cc6bbf6fab341e286add7eb5d16f18d
Autor:
Peter Verstraelen, Samuel Van Remoortel, Nouchin De Loose, Rosanne Verboven, Gerardo Garcia-Diaz Barriga, Anne Christmann, Manuela Gries, Shingo Bessho, Jing Li, Carmen Guerra, Çagla Tükel, Sales Ibiza Martinez, Karl-Herbert Schäfer, Jean-Pierre Timmermans, Winnok H. De Vos
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 18, Iss 1, Pp 89-104 (2024)
Background & Aims: Mounting evidence suggests the gastrointestinal microbiome is a determinant of peripheral immunity and central neurodegeneration, but the local disease mechanisms remain unknown. Given its potential relevance for early diagnosis an
Externí odkaz:
https://doaj.org/article/9e6f75de89f84982823a97136cab22fe
Autor:
Shingo Bessho, Kaitlyn C. M. Grando, Kathrine Kyrylchuk, Amanda Miller, Andres J. Klein-Szanto, Wenhan Zhu, Stefania Gallucci, Vincent Tam, Çagla Tükel
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTThe Salmonella biofilm-associated amyloid protein, curli, is a dominant instigator of systemic inflammation and autoimmune responses following Salmonella infection. Systemic curli injections or infection of mice with Salmonella Typhimurium in
Externí odkaz:
https://doaj.org/article/188e20a58d6241adb0debc0e1f35d22a
1002 Bacterial amyloid curli/eDNA complexes induce NETosis in lupus patients positive for anti-dsDNA
Autor:
Roberto Caricchio, Xinyan Zhang, Stefania Gallucci, Laurie Kilpatrick, Çagla Tükel, Ryan J Pachucki, Lynne Kohler, Sarah Tursi, Lauren Nicastro
Publikováno v:
Lupus Science and Medicine, Vol 9, Iss Suppl 3 (2022)
Externí odkaz:
https://doaj.org/article/fd6f5530c0f546108b4eb31955d614eb
Autor:
Lauren K Nicastro, Jaime de Anda, Neha Jain, Kaitlyn C M Grando, Amanda L Miller, Shingo Bessho, Stefania Gallucci, Gerard C L Wong, Çagla Tükel
Publikováno v:
PLoS Pathogens, Vol 18, Iss 8, p e1010742 (2022)
Deposition of human amyloids is associated with complex human diseases such as Alzheimer's and Parkinson's. Amyloid proteins are also produced by bacteria. The bacterial amyloid curli, found in the extracellular matrix of both commensal and pathogeni
Externí odkaz:
https://doaj.org/article/56383d3daf1e460f8c4ee0d0b60b724a
Autor:
Tam D. Quach, Weiqing Huang, Ranjit Sahu, Catherine M.M. Diadhiou, Chirag Raparia, Roshawn Johnson, Tung Ming Leung, Susan Malkiel, Peta Gay Ricketts, Stefania Gallucci, Çagla Tükel, Chaim O. Jacob, Martin L. Lesser, Yong-Rui Zou, Anne Davidson
Publikováno v:
JCI Insight, Vol 7, Iss 5 (2022)
TNF inhibitors are widely used to treat inflammatory diseases; however, 30%–50% of treated patients develop new autoantibodies, and 0.5%–1% develop secondary autoimmune diseases, including lupus. TNF is required for formation of germinal centers
Externí odkaz:
https://doaj.org/article/0bc079a9637640159ce2bb095af989d7
Autor:
Amanda L. Miller, Lauren K. Nicastro, Shingo Bessho, Kaitlyn Grando, Aaron P. White, Yi Zhang, Gillian Queisser, Bettina A. Buttaro, Çagla Tükel
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Curli, a major component of the bacterial biofilms in the intestinal tract, activates pattern recognition receptors and triggers joint inflammation after infection with Salmonella enterica serovar Typhimurium. The factors that allow S. Typhi
Externí odkaz:
https://doaj.org/article/376f4c26d0db46758ada73f6bae90904
Autor:
Keman Xu, Ying Shao, Fatma Saaoud, Aria Gillespie, Charles Drummer, Lu Liu, Yifan Lu, Yu Sun, Hang Xi, Çagla Tükel, Domenico Pratico, Xuebin Qin, Jianxin Sun, Eric T. Choi, Xiaohua Jiang, Hong Wang, Xiaofeng Yang
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
To determine whether pro-inflammatory lipid lysophosphatidylinositols (LPIs) upregulate the expressions of membrane proteins for adhesion/signaling and secretory proteins in human aortic endothelial cell (HAEC) activation, we developed an EC biology
Externí odkaz:
https://doaj.org/article/c4bf8b0069414bbbb53232479e033ca7
Publikováno v:
Lupus Science and Medicine, Vol 8, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/52111b2a750642c6801fd8e3a82c5aff
Autor:
Roberto Caricchio, Stefania Gallucci, Michael H Lee, Sarah A Tursi, Lauren K Nicastro, Çagla Tükel, Benjamin L Green
Publikováno v:
Lupus Science and Medicine, Vol 8, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/30ac2195e7c44342bd9f33317a796b09