Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Åse-Brit Westvik"'
Autor:
Peter Kierulf, Carola E. Henriksson, Reidun Øvstebø, Åse-Brit Westvik, Olav Klingenberg, Gun-Britt Joø
Publikováno v:
Thrombosis and Haemostasis. 94:1236-1244
SummaryTissue factor (TF), the main initiator of blood coagulation, contributes to the manifestation of disseminated intravascular coagulation following septic shock in meningococcal infection. Since a direct relationship between disease severity and
Autor:
Gun Britt Joø, Peter Kierulf, Reidun Øvstebø, Åse-Brit Westvik, Anne-Sophie W. Møller, Kari-Bente F. Haug
Publikováno v:
Journal of Endotoxin Research. 9:349-360
Regulation of chemokine production and the expression of chemokine receptors play an important role during inflammation and infectious diseases. The present study was designed to study the effects of five different bacterial cell wall components (PAM
Autor:
Peter Kierulf, Gun B. Joø, Per Kr Lund, Reidun Øvstebø, Kari Bente Foss Haug, Åse-Brit Westvik
Publikováno v:
Journal of Immunological Methods. 252:45-55
After developing and applying a method for cryopreserving monocytes, we found a substantial cell loss when culturing these cells. Monocytes were isolated from blood donors by density gradient centrifugation, purified by elutriation and cryopreserved.
Autor:
Peter Kierulf, Reidun Øvstebø, K. B. Foss Haug, Åse-Brit Westvik, L. T. N. Osnes, Gun-Britt Joø
Publikováno v:
Thrombosis and Haemostasis. 83:868-873
SummaryThe effect of aspirin on LPS-incubation of whole blood was investigated. Aspirin induced a concentration dependent increase (2.5–5-fold at 5 mM aspirin) in LPS-induced appearance of TNF-α and fibrinopeptide A (FPA) in plasma, despite the co
Autor:
Reidun Øvstebø, Peter Kierulf, K. B. Foss, Åse-Brit Westvik, L. T. N. Osnes, C. Okkenhaug, Gun-Britt Joø
Publikováno v:
Thrombosis and Haemostasis. 76:0970-0976
SummaryWe have investigated the effects of acetylsalicylic acid and sodium salicylate on the LPS-induced synthesis of the pro-coagulant protein tissue factor (TF) and the pro-inflammatory protein tumor necrosis fac-tor-a (TNF-a), as well as the prost
Publikováno v:
Journal of Endotoxin Research. 2:27-35
We have investigated the role of CD14 in lipopolysaccharide (LPS) stimulation of monocytes to tissue factor (TF) synthesis, tumor necrosis factor (TNF-α) antigen and interleukin-6 (IL-6) antigen release. Elutriation-purified monocytes or peripheral
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 15:11-16
Abstract Tissue factor (TF) on monocyte and macrophage surfaces is a nonproteolytic cofactor for factor VIIa (FVIIa)–induced coagulation. Monocyte-derived macrophages in atherosclerotic plaques express TF, which, after plaque disruption or rupture,
Publikováno v:
Thrombosis Research. 76:373-383
The purpose of this study was to compare the ability of fresh and cryopreserved mononuclear cells to generate thrombin, induce fibrin formation and finally resolve the fibrin formed, when exposed to plasma. Peripheral blood mononuclear cells (PBM) fr
Autor:
Gun Britt Joø, Carola E. Henriksson, Peter Kierulf, Marit Hellum, Kirsti S. Landsverk, Olav Klingenberg, Åse-Brit Westvik
Publikováno v:
Thrombosis research. 119(5)
Introduction Cell surface tissue factor (TF) is normally encrypted, but can be activated by various cellular perturbations. Exposure of TF bearing cells to calcium ionophore has been reported to increase TF activity, de-encrypt TF, by phosphatidylser
Autor:
Gun Britt Joø, Åse-Brit Westvik, Kari Bente Foss Haug, Peter Kierulf, Anne-Sophie W. Møller, Reidun Øvstebø
Publikováno v:
Cytokine. 32(6)
Recognition of conserved bacterial structures called pathogen-associated molecular patterns (PAMPs) by pattern recognition receptors (PRRs), may lead to induction of a variety of "early immediate genes" such as chemokines. In the current study, we ha