Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Åsa Janfalk-Carlsson"'
Publikováno v:
IUCrJ, Vol 5, Iss 3, Pp 269-282 (2018)
The epoxide hydrolase StEH1 catalyzes the hydrolysis of trans-methylstyrene oxide to 1-phenylpropane-1,2-diol. The (S,S)-epoxide is exclusively transformed into the (1R,2S)-diol, while hydrolysis of the (R,R)-epoxide results in a mixture of product e
Externí odkaz:
https://doaj.org/article/a243ec5add574fbe867de47eb5539d4f
Autor:
Linus Olausson, Simon Olofsson, Bo Jacobsson, Jean-Marc Costa, Olof Karlberg, Eva Åström, Kypros H. Nicolaides, Åsa Janfalk-Carlsson, Björn Andersson, Olle Ericsson, Atefeh Mohsenchian, Björn Skarpås, Faizan Hakamali, Tarja Ahola, Anna Sahlberg, Aino Fianu-Jonasson, Johanna Lundgren, Filip Karlsson, Fredrik Dahl, Ida Alftrén, Atif Qureshi, Niels Francois, Per-Ola Forsgren, Jenny Dahlberg, Anna Gousseva, Emelie Barkenäs, Fredrik Roos, Anna Sävneby, Fredrik Persson, Birgit Brandner, Henrik Johansson, Ani Boghos, Jérémie Gautier, Peter Svahn
Publikováno v:
Prenatal Diagnosis
Objective To evaluate clinical performance of a new automated cell‐free (cf)DNA assay in maternal plasma screening for trisomies 21, 18, and 13, and to determine fetal sex. Method Maternal plasma samples from 1200 singleton pregnancies were analyze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5b6f611256dbdaa518b32f30cba5d98
http://europepmc.org/articles/PMC6899636
http://europepmc.org/articles/PMC6899636
Autor:
Olle Ericsson, Tarja Ahola, Fredrik Dahl, Filip Karlsson, Fredrik Persson, Olof Karlberg, Fredrik Roos, Ida Alftrén, Björn Andersson, Emelie Barkenäs, Ani Boghos, Birgit Brandner, Jenny Dahlberg, Per‐Ola Forsgren, Niels Francois, Anna Gousseva, Faizan Hakamali, Åsa Janfalk‐Carlsson, Henrik Johansson, Johanna Lundgren, Atefeh Mohsenchian, Linus Olausson, Simon Olofsson, Atif Qureshi, Björn Skarpås, Peter Svahn, Anna Sävneby, Eva Åström, Anna Sahlberg, Aino Fianu‐Jonasson, Jérémie Gautier, Jean‐Marc Costa, Bo Jacobsson, Kypros Nicolaides
Publikováno v:
Prenatal Diagnosis. 39
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bc1741d6b454c943c0c00327bed745f
https://doi.org/10.1002/pd.5585
https://doi.org/10.1002/pd.5585
Autor:
S. C. Lynn Kamerlin, Paul Bauer, Mikael Nilsson, Doreeen Dobritzsch, Åsa Janfalk Carlsson, Mikael Widersten
Publikováno v:
'ChemBioChem ', vol: 17, pages: 1693-1697 (2016)
Chembiochem
Chembiochem
Engineered enzyme variants of potato epoxide hydrolase (StEH1) display varying degrees of enrichment of (2R)-3-phenylpropane-1,2-diol from racemic benzyloxirane. Curiously, the observed increase in the enantiomeric excess of the (R)-diol is not only
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1431960f10dee305fb49ef5d9be2d615
https://epn-library.esrf.fr/flora/jsp/index_view_direct_anonymous.jsp?record=doc:PUB_ESRF:45469
https://epn-library.esrf.fr/flora/jsp/index_view_direct_anonymous.jsp?record=doc:PUB_ESRF:45469
Autor:
Magnus Eriksson, Atefeh Mohsenchian, Helena Kopp-Kallner, Johanna Lundgren, Birgit Brandner, Fredrik Persson, Simon Olofsson, Magnus Westgren, Mathias Howell, Björn Skarpås, Aino Fianu-Jonasson, Tarja Ahola, Henrik Johansson, Per-Ola Forsgren, Anna Gousseva, Argyro Syngelaki, Filip Karlsson, Faizan Hakamali, Fredrik Dahl, Linus Olausson, Sara Elfman, Eva Åström, Atif Qureshi, Emelie Barkenäs, Johan Stenberg, Anna Sävneby, Jenny Dahlberg, Ove Öhman, Ida Alftrén, Niels Francois, Olof Karlberg, Kypros H. Nicolaides, Björn Andersson, Åsa Janfalk-Carlsson, Olle Ericsson, Fredrik Roos
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Scientific Reports
Scientific Reports
Cell-free DNA analysis is becoming adopted for first line aneuploidy screening, however for most healthcare programs, cost and workflow complexity is limiting adoption of the test. We report a novel cost effective method, the Vanadis NIPT assay, desi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40a52ef2bc4e3196ba1d26dadbe219cf
https://doi.org/10.1038/s41598-018-22606-0
https://doi.org/10.1038/s41598-018-22606-0
Autor:
Paul Bauer, Mikael Widersten, Agata Naworyta, Åsa Janfalk Carlsson, Sherry L. Mowbray, Fernanda Duarte, Shina Caroline Lynn Kamerlin, Beat Anton Amrein
Publikováno v:
ACS Catalysis
Potato epoxide hydrolase 1 exhibits rich enantio- and regioselectivity in the hydrolysis of a broad range of substrates. The enzyme can be engineered to increase the yield of optically pure products as a result of changes in both enantio- and regiose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df9d4237b8b67195e335e42ca5caa040
https://doi.org/10.1021/acscatal.5b01639
https://doi.org/10.1021/acscatal.5b01639
Publikováno v:
Biochemistry. 51:7627-7637
Enzyme variants of the plant epoxide hydrolase StEH1 displaying improved stereoselectivities in the catalyzed hydrolysis of (2,3-epoxypropyl)benzene were generated by directed evolution. The evolution was driven by iterative saturation mutagenesis in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::143756e412f44d07776364ebf49b83d3
https://doi.org/10.1021/bi3007725
https://doi.org/10.1021/bi3007725
Autor:
João Rm Almeida, Boaz Laadan, Marie F. Gorwa-Grauslund, Valeria Wallace-Salinas, Peter Rådström, Åsa Janfalk Carlsson
Publikováno v:
Microbial Cell Factories
Background A previously discovered mutant of Saccharomyces cerevisiae alcohol dehydrogenase 1 (Adh1p) was shown to enable a unique NADH-dependent reduction of 5-hydroxymethylfurfural (HMF), a well-known inhibitor of yeast fermentation. In the present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777d319712d21dda4e7b7e5b8fe02186
https://pubmed.ncbi.nlm.nih.gov/25287956
https://pubmed.ncbi.nlm.nih.gov/25287956
Publikováno v:
Biochemistry. 55:1940-1940
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::755dfbf1c00126c9a079f8637bdf8cda
https://doi.org/10.1021/acs.biochem.6b00197
https://doi.org/10.1021/acs.biochem.6b00197