Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Åsa Ehlén"'
Autor:
Åsa Ehlén, Charlotte Martin, Simona Miron, Manon Julien, François-Xavier Theillet, Virginie Ropars, Gaetana Sessa, Romane Beaurepere, Virginie Boucherit, Patricia Duchambon, Ahmed El Marjou, Sophie Zinn-Justin, Aura Carreira
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
The BRCA2 tumour suppressor protein is known to play an important role in homologous recombination. Here the authors reveal how the phosphorylation of BRCA2 by Polo-like kinase 1 (PLK1) contributes to the regulation of mitosis.
Externí odkaz:
https://doaj.org/article/1172298aed5c403d86de4c53b25b80bd
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
BRCA2 is a well-characterized central player in homologous recombination in which it functions as the RAD51 loader. Here the authors identify an N-terminal region of BRCA2 that binds DNA and promotes efficient DNA repair.
Externí odkaz:
https://doaj.org/article/3736af5edec74ca0b1a798200ee895a5
Autor:
Keqiang Ye, Jenny L. Persson, Jing Chen, Hanna Khoury, Shaozhong Dong, Åsa Ehlén, Seung-ju Yang, Sung-Wuk Jang
Supplementary Figure 2 from Serine/Arginine Protein–Specific Kinase 2 Promotes Leukemia Cell Proliferation by Phosphorylating Acinus and Regulating Cyclin A1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2394f3d163a34273a037d363a091af2c
https://doi.org/10.1158/0008-5472.22370060
https://doi.org/10.1158/0008-5472.22370060
Autor:
Keqiang Ye, Jenny L. Persson, Jing Chen, Hanna Khoury, Shaozhong Dong, Åsa Ehlén, Seung-ju Yang, Sung-Wuk Jang
Serine/arginine (SR) protein–specific kinase (SRPK), a family of cell cycle–regulated protein kinases, phosphorylate SR domain–containing proteins in nuclear speckles and mediate the pre-mRNA splicing. However, the physiologic roles of this eve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64989f828b9aeec8fb28af0e189086cb
https://doi.org/10.1158/0008-5472.c.6496250
https://doi.org/10.1158/0008-5472.c.6496250
Autor:
Keqiang Ye, Jenny L. Persson, Jing Chen, Hanna Khoury, Shaozhong Dong, Åsa Ehlén, Seung-ju Yang, Sung-Wuk Jang
Supplementary Figure 1 from Serine/Arginine Protein–Specific Kinase 2 Promotes Leukemia Cell Proliferation by Phosphorylating Acinus and Regulating Cyclin A1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08792d192a6140f1819882123c0da748
https://doi.org/10.1158/0008-5472.22370063.v1
https://doi.org/10.1158/0008-5472.22370063.v1
Autor:
Keqiang Ye, Jenny L. Persson, Jing Chen, Hanna Khoury, Shaozhong Dong, Åsa Ehlén, Seung-ju Yang, Sung-Wuk Jang
Supplementary Figure 3 from Serine/Arginine Protein–Specific Kinase 2 Promotes Leukemia Cell Proliferation by Phosphorylating Acinus and Regulating Cyclin A1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b73865192c9ddc76eb941d115004063
https://doi.org/10.1158/0008-5472.22370057
https://doi.org/10.1158/0008-5472.22370057
Publikováno v:
Cell Cycle
Chromosomal instability is a hallmark of cancer. The tumor suppressor protein BRCA2 performs an important role in the maintenance of genome integrity particularly in interphase; as a mediator of homologous recombination DNA repair pathway, it partici
Publikováno v:
Methods in Molecular Biology: Homologous Recombination
Methods in Molecular Biology: Homologous Recombination, pp.115-126, 2021, ⟨10.1007/978-1-0716-0644-5_9⟩
Homologous Recombination
Homologous Recombination, pp.115-126, 2021, ⟨10.1007/978-1-0716-0644-5_9⟩
Homologous Recombination ISBN: 9781071606438
Methods in Molecular Biology: Homologous Recombination, pp.115-126, 2021, ⟨10.1007/978-1-0716-0644-5_9⟩
Homologous Recombination
Homologous Recombination, pp.115-126, 2021, ⟨10.1007/978-1-0716-0644-5_9⟩
Homologous Recombination ISBN: 9781071606438
DNA double-strand breaks (DSBs) are among the most toxic lesions. This type of DNA damage is repaired by two major pathways, homologous recombination (HR), operating only in S/G2 cell-cycle phases and nonhomologous end joining (NHEJ) which is operati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f619d926e7878cc5fc64e0216a6b1c1
https://hal.archives-ouvertes.fr/hal-03065043
https://hal.archives-ouvertes.fr/hal-03065043
Autor:
Sylvain Martineau, Andrés Aguilera, Damarys Loew, Gaetana Sessa, Charlotte Martin, Belén Gómez-González, Sonia Barroso, Juan S Martinez, Åsa Ehlén, Sonia Silva, Bérangère Lombard, Aura Carreira, Stephan Vagner, Carmen Pérez-Calero, Romane Beaurepere
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
idUS. Depósito de Investigación de la Universidad de Sevilla
EMBO Journal
EMBO Journal, EMBO Press, 2021, 40 (7), pp.e106018. ⟨10.15252/embj.2020106018⟩
idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
The EMBO Journal
EMBO J
instname
idUS. Depósito de Investigación de la Universidad de Sevilla
EMBO Journal
EMBO Journal, EMBO Press, 2021, 40 (7), pp.e106018. ⟨10.15252/embj.2020106018⟩
idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
The EMBO Journal
EMBO J
The BRCA2 tumor suppressor is a DNA double-strand break (DSB) repair factor essential for maintaining genome integrity. BRCA2-deficient cells spontaneously accumulate DNA-RNA hybrids, a known source of genome instability. However, the specific role o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66fa45e56f043cfb351bb29e4dbe866f
http://hdl.handle.net/10261/259110
http://hdl.handle.net/10261/259110
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2153
DNA double-strand breaks (DSBs) are among the most toxic lesions. This type of DNA damage is repaired by two major pathways, homologous recombination (HR), operating only in S/G2 cell-cycle phases and nonhomologous end joining (NHEJ) which is operati