Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Åsa E. Y. Engqvist-Goldstein"'
Autor:
Claire X. Zhang, Barbara Pauly, David G. Drubin, Christophe Le Clainche, Kimberley Cunningham, Åsa E. Y. Engqvist-Goldstein
Publikováno v:
The EMBO Journal. 26:1199-1210
Actin polymerization plays a critical role in clathrin-mediated endocytosis in many cell types, but how polymerization is regulated is not known. Hip1R may negatively regulate actin assembly during endocytosis because its depletion increases actin as
Autor:
Sébastien Carréno, Elizabeth Smythe, David G. Drubin, Claire X. Zhang, Åsa E. Y. Engqvist-Goldstein, David J. Owen
Publikováno v:
Traffic. 6:1103-1113
Cyclin G-associated kinase (GAK), also known as auxilin 2, is a potential regulator of clathrin-mediated membrane trafficking. It possesses a kinase domain at its N-terminus that can phosphorylate the clathrin adaptors AP-1 and AP-2 in vitro. The GAK
Autor:
Claire X. Zhang, Sébastien Carréno, David G. Drubin, Åsa E. Y. Engqvist-Goldstein, Kent L. McDonald
Publikováno v:
The Journal of Cell Biology
In diverse species, actin assembly facilitates clathrin-coated vesicle (CCV) formation during endocytosis. This role might be an adaptation specific to the unique environment at the cell cortex, or it might be fundamental, facilitating CCV formation
Publikováno v:
Annual Review of Cell and Developmental Biology. 19:287-332
▪ Abstract Internalization of receptors, lipids, pathogens, and other cargo at the plasma membrane involves several different pathways and requires coordinated interactions between a variety of protein and lipid molecules. The actin cytoskeleton is
Autor:
John E. Heuser, James H. Keen, Robin A. Warren, Åsa E. Y. Engqvist-Goldstein, David G. Drubin, Michael M. Kessels
Publikováno v:
The Journal of Cell Biology
Huntingtin-interacting protein 1 related (Hip1R) is a novel component of clathrin-coated pits and vesicles and is a mammalian homologue of Sla2p, an actin-binding protein important for both actin organization and endocytosis in yeast. Here, we demons
Autor:
Lu Gan, Donald W. Nicholson, Åsa E. Y. Engqvist-Goldstein, Roshni R. Singaraja, Michael R. Hayden, Keith Fichter, Vikramjit Chopra, Martina Metzler, David G. Drubin, Dita M. Rasper, Krista McCutcheon
Publikováno v:
Mammalian Genome. 11:1006-1015
Huntingtin-interacting protein I (HIP1) is a membrane-associated protein that interacts with huntingtin, the protein altered in Huntington disease. HIP1 shows homology to Sla2p, a protein essential for the assembly and function of the cytoskeleton an
Publikováno v:
Molecular Biology of the Cell. 11:393-412
Yeast Abp1p is a cortical actin cytoskeleton protein implicated in cytoskeletal regulation, endocytosis, and cAMP-signaling. We have identified a gene encoding a mouse homologue of Abp1p, and it is identical to SH3P7, a protein shown recently to be a
Autor:
Åsa E. Y. Engqvist-Goldstein, Michael R. Hayden, Vikramjit Chopra, Michael M. Kessels, David G. Drubin
Publikováno v:
The Journal of Cell Biology
The actin cytoskeleton has been implicated in endocytosis, yet few molecules that link these systems have been identified. Here, we have cloned and characterized mHip1R, a protein that is closely related to huntingtin interacting protein 1 (Hip1). Th
Autor:
Consuelo Barroso, John E. Heuser, Sébastien Carréno, Claire X. Zhang, Åsa E. Y. Engqvist-Goldstein, David G. Drubin
Actin filaments transiently associate with the endocytic machinery during clathrin-coated vesicle formation. Although several proteins that might mediate or regulate this association have been identified, in vivo demonstration of such an activity has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b25ef133584e304abc6fcd6d6b140a17
https://europepmc.org/articles/PMC379265/
https://europepmc.org/articles/PMC379265/