Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Åke Wasteson"'
Publikováno v:
Journal of Drug Targeting. 17:268-277
Glioblastoma multiforme (GBM) is an unusually aggressive brain tumor; it is also highly heterogeneous. Poor prognosis and a median survival of less than 1 year, using conventional treatment, calls for development of new treatment strategies. Overexpr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25783e63b6eab4cdd1ceeb1c2839a88c
https://doi.org/10.1080/10611860902718698
https://doi.org/10.1080/10611860902718698
Publikováno v:
Scandinavian Journal of Rheumatology. 34:204-211
Cell types present in synovial joint tissues and during synovitis are known to produce epidermal growth factor receptor (EGFR)/ErbB-1/HER-1 and the potent EGFR-ligand transforming growth factor-alpha (TGF-alpha) in vitro. Concomitant expression of TG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::613f3aaf6919e125ffba47433db11cc1
https://doi.org/10.1080/03009740510017715
https://doi.org/10.1080/03009740510017715
Publikováno v:
Cancer Letters. 146:189-194
The pattern of susceptibility of malignant cells to the cytostatic drug suramin is not fully clarified. Therefore, in the present paper we have assessed the effects of suramin on the growth of eight cell lines derived from human malignant fibrous his
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7c3a7d45a3ee27f01ca51f23217b98c
https://doi.org/10.1016/s0304-3835(99)00260-8
https://doi.org/10.1016/s0304-3835(99)00260-8
Publikováno v:
European Journal of Cancer. 34:2094-2100
Eight human malignant fibrous histiocytomas were examined in vitro, in order to relate their growth properties to mRNA expression for platelet-derived growth factor (PDGF), PDGF receptor (PDGF-R), transforming growth factor-alpha (TGF-alpha) and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::795d3f97c90145d8d48eff3f8437f233
https://doi.org/10.1016/s0959-8049(98)00247-0
https://doi.org/10.1016/s0959-8049(98)00247-0
Publikováno v:
Blood. 85:2385-2392
The expression of transforming growth factor-alpha (TGF-alpha) in human differentiating leukemic cell lines and in circulating human eosinophils prompted the search for an analogous function in normal human bone marrow (BM) cells. Immunohistochemistr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82eabc0f7a2911079ca0e283fff80903
https://doi.org/10.1182/blood.v85.9.2385.bloodjournal8592385
https://doi.org/10.1182/blood.v85.9.2385.bloodjournal8592385
Publikováno v:
Journal of neuro-oncology. 68(3)
It has been shown that human malignant glioma tumours consist of several subpopulations of tumour cells. Due to heterogeneity and different degrees of vascularisation cell subpopulations possess varying resistance to chemo- or radiation therapy. Ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20f163c0a48619d9343d96900dbfc7b3
https://pubmed.ncbi.nlm.nih.gov/15332322
https://pubmed.ncbi.nlm.nih.gov/15332322
Publikováno v:
Bioscience reports. 21(3)
We have previously reported that the human monocytoid cell line U-937-1 constitutively expresses transforming growth factor-alpha (TGF-α) and that the steady-state levels of TGF-α mRNA as well as TGF-α protein release increase when U-937-1 cells a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::313f7aae8e5b736a3995e952cc568f04
https://pubmed.ncbi.nlm.nih.gov/11892999
https://pubmed.ncbi.nlm.nih.gov/11892999
Publikováno v:
Bioscience reports. 20(2)
When the receptors for platelet-derived growth factor (PDGF) are activatedthey aggregate, become tyrosine-phosphorylated and elicit a cascade ofdown-stream signals, including mobilization of Ca2+ from intra- andextracellular stores. Receptor mobility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1b5bb6c08395ed5b8aa9ea271564f2e
https://pubmed.ncbi.nlm.nih.gov/10965969
https://pubmed.ncbi.nlm.nih.gov/10965969
Publikováno v:
Life sciences. 62(21)
The kinetics of exogenously given 125 I-platelet-derived growth factor-AB (PDGF-AB) was studied in mice. 125 I-PDGF-AB was injected either intraperitoneally, intramuscularly or subcutaneously and the resulting concentrations of 125 I-radioactivity mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc2c4a06d8059e97b16f0a1aa3795f02
https://pubmed.ncbi.nlm.nih.gov/9619839
https://pubmed.ncbi.nlm.nih.gov/9619839
Publikováno v:
Bioscience reports. 16(3)
Growth factor receptors transmit biological signals for the stimulation of cell growth in vitro and in vivo and their autocrine stimulation may be involved in tumorigenesis. It is therefore, of great value to understand receptor reactions in response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ab33aca5966c1c4319c54c41641b8f5
https://pubmed.ncbi.nlm.nih.gov/8842373
https://pubmed.ncbi.nlm.nih.gov/8842373