Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ângela Amaro-Leal"'
Autor:
Liana Shvachiy, Ângela Amaro-Leal, Filipa Machado, Isabel Rocha, Tiago F. Outeiro, Vera Geraldes
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 711 (2024)
Lead exposure is a significant health concern, ranking among the top 10 most harmful substances for humans. There are no safe levels of lead exposure, and it affects multiple body systems, especially the cardiovascular and neurological systems, leadi
Externí odkaz:
https://doaj.org/article/cb8fca00329e407b8cac5c516ddd4b9c
Publikováno v:
Biology, Vol 12, Iss 7, p 1031 (2023)
Doxorubicin (DOX) is commonly used in several chemotherapies to treat various cancers, but it is known to cause cardiotoxicity and cardiac symptoms. Autonomic dysfunction is thought to contribute to the cardiotoxic effects of DOX, but the specific do
Externí odkaz:
https://doaj.org/article/9bd6dc3242db4c9da80fc7ee0ccf16df
Publikováno v:
Cells, Vol 12, Iss 5, p 818 (2023)
The nervous system is the primary target for lead exposure and the developing brain appears to be especially susceptible, namely the hippocampus. The mechanisms of lead neurotoxicity remain unclear, but microgliosis and astrogliosis are potential can
Externí odkaz:
https://doaj.org/article/3b09162678e743a580e606598e8392dc
Publikováno v:
Biology, Vol 11, Iss 8, p 1164 (2022)
Lead is a heavy metal whose widespread use has resulted in environmental contamination and significant health problems, particularly if the exposure occurs during developmental stages. It is a cumulative toxicant that affects multiple systems of the
Externí odkaz:
https://doaj.org/article/0950257ebc3e4899b4ed759b906af294
Autor:
Ângela Amaro-Leal
Publikováno v:
Annals of Medicine, Vol 53, Iss sup1, Pp S5-S5 (2021)
AbstractSepsis is a systemic inflammatory state mediated by the innate immune system resulting in an excessive cellular response to severe infection, with high levels of morbidity and mortality. Furthermore, patients who survive sepsis, have long-ter
Externí odkaz:
https://doaj.org/article/fadf9ae8933f41e2990d458f2049c410
Autor:
Vera Geraldes, Elisa Caldeira, Ana Afonso, Filipa Machado, Ângela Amaro-Leal, Sergio Laranjo, Isabel Rocha
Publikováno v:
The Open Cardiovascular Medicine Journal. 16
Breast cancer is the most frequent malignant disease among women, being responsible for a considerable percentage of fatalities and comorbidities every year. Despite advances in early detection and therapy, evidence shows that breast cancer survivors
Publikováno v:
SSRN Electronic Journal.
Publikováno v:
European Heart Journal. 42
Doxorubicin (DOX) is a chemotherapeutic agent that improves the survival and quality of life of patients with solid tumours. However, these improvements are counterbalanced by various dose-dependent side effects including cardiac dysfunction, which m
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
© 2020 Springer Nature Switzerland AG. Part of Springer Nature.
Long-term lead (Pb) exposure alters the normal development of the nervous system and physiology. It affects multiple organ systems, causing hypertension, cardiorespiratory dysfunct
Long-term lead (Pb) exposure alters the normal development of the nervous system and physiology. It affects multiple organ systems, causing hypertension, cardiorespiratory dysfunct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0459857890d2798dd5390b59f8601a07
Publikováno v:
Frontiers in Cellular Neuroscience. 13