Výsledky vyhledávání - "Áquila S.B. Portela"

Identification of immune biomarkers related to disease progression and treatment efficacy in human visceral leishmaniasis

Autor: Fernanda F. Ramos, Eduardo A.F. Coelho, Regina Lunardi Rocha, Lourena E. Costa, Vívian T. Martins, Fabiana Rocha Da Silva, Amanda S. Machado, Áquila S.B. Portela, Antônio Lúcio Teixeira, Isabela S. Gama, Rachel B. Caligiorne, Thaís T.O. Santos, Mariana P. Lima, Daniela P. Lage, Beatriz C.S. Salles, Daniela R. Lessa, Guilherme F. Nascimento, Manoel Otávio da Costa Rocha, Miguel A. Chávez-Fumagalli

Publikováno v: Immunobiology. 223:303-309

Visceral leishmaniasis (VL) is a potentially fatal disease, in which the treatment based on chemotherapy is considered toxic. The cure of disease is associated with the life-long Th1-type immunity against the infection. The Th1-related cytokines prod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::864fc1cf86147b912dc31de32776e9c1
https://doi.org/10.1016/j.imbio.2017.10.043

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Canine visceral leishmaniasis: Detection of Leishmania spp. genome in peripheral blood of seropositive dogs by real-time polymerase chain reaction (rt-PCR)

Autor: Fabiana Rocha-Silva, Amanda S. Machado, Áquila S.B. Portela, Rachel B. Caligiorne, Eduardo A.F. Coelho, Lourena E. Costa, Sônia Maria de Figueiredo, Cidiane Graciele-Melo, Cláudia Barbosa Assunção, Fabrício Moreira Monteiro

Publikováno v: Microbial pathogenesis. 126

Visceral leishmaniasis (VL) is a zoonosis caused by the protozoa of the genus Leishmania. Among the species, L. infantum and/or L. infantum (chagasi) are the most important species affecting the Americas. Domestic dogs are the main reservoir of the p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::627d6a42a07012d5bbd616520c2cfd8d
https://pubmed.ncbi.nlm.nih.gov/30419342

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Serological diagnosis and prognostic of tegumentary and visceral leishmaniasis using a conserved Leishmania hypothetical protein

Autor: Rachel B. Caligiorne, Miguel A. Chávez-Fumagalli, Thaís T.O. Santos, Jamil S. Oliveira, Patrícia A.F. Ribeiro, Denise Utsch Gonçalves, Fernanda F. Ramos, Alexsandro Sobreira Galdino, Lourena E. Costa, Danielle F. de Magalhães-Soares, Daniel Dias, Áquila S.B. Portela, Mariana C. Duarte, Daniela P. Lage, Eduardo A.F. Coelho, Daniel Menezes-Souza, Beatriz C.S. Salles, Gerusa B. Carvalho, Eduardo Silva

Publikováno v: Parasitology international. 67(3)

New candidates for serological markers against leishmaniasis are required to be identified, since the presence of high titers of anti-Leishmania antibodies remain detected in sera of treated and cured patients, when current antigens have being employ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::336fa10e5016bc4d330968b523613b4e
https://pubmed.ncbi.nlm.nih.gov/29408435

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Recombinant prohibitin protein of Leishmania infantum acts as a vaccine candidate and diagnostic marker against visceral leishmaniasis

Publikováno v: Cellular immunology. 323

Visceral leishmaniasis (VL) represents a serious public health problem, as Leishmania infantum is one of main disease causative agents in the Americas. In a previous immunoproteomic study, the prohibitin (PHB) protein was identified in L. infantum pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0169d8ca42a014cf658f892b708a0ff
https://pubmed.ncbi.nlm.nih.gov/29128045

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Recombinant small glutamine-rich tetratricopeptide repeat-containing protein of Leishmania infantum: Potential vaccine and diagnostic application against visceral leishmaniasis

Publikováno v: Molecular immunology. 91

Different Leishmania proteins have been evaluated in order to find a potential vaccine candidate or diagnostic marker capable of providing long lasting protection against infection or helping to identify infected mammalian hosts, respectively. Howeve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3907bad33dc9849af4c2b63a3effc87
https://pubmed.ncbi.nlm.nih.gov/28988041

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Antigenicity of phage clones and their synthetic peptides for the serodiagnosis of canine and human visceral leishmaniasis

Autor: Daniel Menezes-Souza, Lourena E. Costa, Mayara I. S. Lima, Beatriz C.S. Salles, Danielle F. de Magalhães-Soares, Eduardo A.F. Coelho, Julia A.G. Silveira, Luiz Ricardo Goulart, Mariana P. Lima, Ricardo Andrez Machado-de-Ávila, Mariana C. Duarte, Miguel A. Chávez-Fumagalli, Fernanda F. Ramos, Thaís T.O. Santos, Áquila S.B. Portela

Publikováno v: Microbial pathogenesis. 110

In the Americas, Brazil is responsible by 90% of the cases registered of visceral leishmaniasis (VL), and Leishmania infantum is the most common parasite species responsible by disease in Brazilian dogs and humans. A precise diagnosis may allow to a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba92df2508a414028a2e90cd22e86fe2
https://pubmed.ncbi.nlm.nih.gov/28629727

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An ELISA immunoassay employing a conserved Leishmania hypothetical protein for the serodiagnosis of visceral and tegumentary leishmaniasis in dogs and humans

Autor: Danielle F. de Magalhães-Soares, Mariana P. Lima, Beatriz C.S. Salles, Bruna T. Silvestre, Lourena E. Costa, Ana Maria Ravena Severino Carvalho, Miguel A. Chávez-Fumagalli, Bruno Mendes Roatt, Mariana C. Duarte, Denise Utsch Gonçalves, Daniel Menezes-Souza, Áquila S.B. Portela, Eduardo A.F. Coelho, Julia A.G. Silveira, Fernanda F. Ramos, Thaís T.O. Santos

Publikováno v: Cellular immunology. 318

In the present study, a conserved Leishmania hypothetical protein, namely LiHypA, was evaluated for the serodiagnosis of visceral and tegumentary leishmaniasis in dogs and humans. This protein showed a high amino acid sequence homology between viscer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7333e2c97dd02b636a61b70fc0b934c3
https://pubmed.ncbi.nlm.nih.gov/28602279

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