Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ángela del Águila"'
Autor:
Ángela del Águila, Ran Zhang, Xinyuan Yu, Lihong Dang, Feng Xu, Jin Zhang, Vaibhav Jain, Jilin Tian, Xiao-Ping Zhong, Huaxin Sheng, Wei Yang
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-21 (2024)
Abstract Background Ischemic stroke elicits a complex and sustained immune response in the brain. Immunomodulatory treatments have long held promise for improving stroke outcomes, yet none have succeeded in the clinical setting. This lack of success
Externí odkaz:
https://doaj.org/article/848dab080e1b4085bd4aa81a6c92e9c9
Autor:
Zhuoran Wang, Qiang Li, Brad J. Kolls, Brian Mace, Shu Yu, Xuan Li, Wei Liu, Eduardo Chaparro, Yuntian Shen, Lihong Dang, Ángela del Águila, Joshua D. Bernstock, Kory R. Johnson, Junjie Yao, William C. Wetsel, Scott D. Moore, Dennis A. Turner, Wei Yang
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
XBP1s is a key effector of the unfolded protein response. Neuron-specific overexpression of Xbp1s in the brain leads to impaired GABAergic signaling and recurrent spontaneous seizures in mice.
Externí odkaz:
https://doaj.org/article/41145015ec054931bd78b62feab0a1cb
Publikováno v:
Photoacoustics, Vol 29, Iss , Pp 100444- (2023)
We present an ischemic stroke study using our newly-developed PAUSAT system that integrates photoacoustic computed tomography (PACT), high-frequency ultrasound imaging, and acoustic angiographic tomography. PAUSAT is capable of three-dimensional (3D)
Externí odkaz:
https://doaj.org/article/63f76f728c90446984b16b5c06e0f00f
Autor:
Xuan Li, Jingjun Lyu, Ran Li, Vaibhav Jain, Yuntian Shen, Ángela del Águila, Ulrike Hoffmann, Huaxin Sheng, Wei Yang
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-8 (2022)
Abstract Background Ischemic stroke is a medical emergency that primarily affects the elderly. A complex immune response in the post-stroke brain constitutes a key component of stroke pathophysiology. This study aimed to determine how stroke affects
Externí odkaz:
https://doaj.org/article/43d798b4ba404a69ae64ce3d4a6d98e1
Autor:
Rodrigo M. Maza, María Asunción Barreda-Manso, David Reigada, Ágata Silván, Teresa Muñoz-Galdeano, Altea Soto, Ángela del Águila, Manuel Nieto-Díaz
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1559 (2022)
The central nervous system microRNA miR-138-5p has attracted much attention in cancer research because it inhibits pro-apoptotic genes including CASP3. We hypothesize that miR-138-5p downregulation after SCI leads to overexpression of pro-apoptotic g
Externí odkaz:
https://doaj.org/article/bc7faf3326e64ae2b14a8c259184571d
Autor:
Teresa Muñoz-Galdeano, David Reigada, Ángela del Águila, Irene Velez, Marcos J. Caballero-López, Rodrigo M. Maza, Manuel Nieto-Díaz
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Autophagy is an essential process of cellular waist clearance that becomes altered following spinal cord injury (SCI). Details on these changes, including timing after injury, underlying mechanisms, and affected cells, remain controversial. Here we p
Externí odkaz:
https://doaj.org/article/8022337ce196416ca50a99b29d4db6e3
Publikováno v:
Photoacoustics. 29
We present an ischemic stroke study using our newly-developed PAUSAT system that integrates photoacoustic computed tomography (PACT), high-frequency ultrasound imaging, and acoustic angiographic tomography. PAUSAT is capable of three-dimensional (3D)
Autor:
Ángela del Águila, Mike Adam, Kristy Ullom, Nicholas Shaw, Shenyue Qin, Jacqueline Ehrman, Diana Nardini, Joseph Salomone, Brian Gebelein, Q. Richard Lu, Steven S. Potter, Ronald Waclaw, Kenneth Campbell, Masato Nakafuku
Publikováno v:
Development
Distinct neural stem cells (NSCs) reside in different regions of the subventricular zone (SVZ) and generate multiple olfactory bulb (OB) interneuron subtypes in the adult brain. However, the molecular mechanisms underlying such NSC heterogeneity rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef3c118e026d1a51b1ada14104283639
https://europepmc.org/articles/PMC8959153/
https://europepmc.org/articles/PMC8959153/
Autor:
Xuan Li, Jingjun Lyu, Ran Li, Vaibhav Jain, Yuntian Shen, Ángela del Águila, Ulrike Hoffmann, Huaxin Sheng, Wei Yang
Publikováno v:
Journal of neuroinflammation. 19(1)
Background Ischemic stroke is a medical emergency that primarily affects the elderly. A complex immune response in the post-stroke brain constitutes a key component of stroke pathophysiology. This study aimed to determine how stroke affects immune ce
Autor:
Andrés Ángel Calderón-García, Manuel Nieto-Díaz, Teresa Muñoz-Galdeano, Rodrigo M. Maza, David Reigada, Manuel Soto‐Catalán, Ángela del Águila
Publikováno v:
Journal of Neurochemistry. 151:116-130
Excitotoxic cell death because of the massive release of glutamate and ATP contributes to the secondary extension of cellular and tissue loss following traumatic spinal cord injury (SCI). Evidence from blockage experiments suggests that over-expressi